Page last updated: 2024-11-03

procaterol and Muscle Relaxation

procaterol has been researched along with Muscle Relaxation in 16 studies

Procaterol: A long-acting beta-2-adrenergic receptor agonist.

Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.

Research Excerpts

ExcerptRelevanceReference
" Conversely, the IAS smooth muscle relaxation caused by beta(1)- and beta(2)-AR agonists (xamoterol and procaterol, respectively) was selectively antagonized by their respective antagonists CGP 20712 [(+/-)-2-hydroxy-5-[2-[[2-hydroxy-3-[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenoxy]propyl]amino]ethoxy]-benzamide methanesulfonate salt] and ICI 118551."3.72Functional and molecular characterization of beta-adrenoceptors in the internal anal sphincter. ( Banwait, K; Kazerounian, S; Rathi, S; Rattan, S; Schulz, S; Waldman, SA, 2003)
"The purpose of the present study was to ascertain the role of adenylate (AC) versus guanylate cyclase (GC) signaling pathways in the internal anal sphincter (IAS) smooth muscle relaxation by beta(1)-, beta(2)-, and beta(3)-adrenoceptor (AR) activation by xamoterol, procaterol, and disodium 5-[(2R)-2-(3-chlorophenyl)-2-hydroxy-ethyl]amino)propyl]-1,3-benzodioxole-2,2-dicarboxylate (CL 316243), respectively."3.72Role of adenylate and guanylate cyclases in beta1-, beta2-, and beta3-adrenoceptor-mediated relaxation of internal anal sphincter smooth muscle. ( De Godoy, M; Li, F; Rattan, S, 2004)
"We examined the effects of four beta 2-agonists, clenbuterol, metaproterenol, procaterol, and albuterol, on the contractility of fatigued canine diaphragm."3.68Effects of beta 2-agonists on the contractility of fatigued canine diaphragm in vivo. ( Miyashita, A; Numata, H; Okubo, T; Suzuki, M; Suzuki, S, 1993)
"Prazosin was 300 times more active than rauwolscine in inhibiting NA-induced contractions."1.27Comparison of the responses to drugs acting on adrenoreceptors and muscarinic receptors in human isolated corpus cavernosum and cavernous artery. ( Andersson, KE; Hedlund, H, 1985)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's6 (37.50)18.2507
2000's6 (37.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rathi, S1
Kazerounian, S1
Banwait, K1
Schulz, S1
Waldman, SA1
Rattan, S2
Takeda, H3
Matsuzawa, A1
Igawa, Y3
Yamazaki, Y3
Kaidoh, K1
Akahane, S1
Kojima, M1
Miyata, H1
Akahane, M3
Nishizawa, O3
Li, F1
De Godoy, M1
Badawi, JK1
Uecelehan, H1
Hatzinger, M1
Michel, MS1
Haferkamp, A1
Bross, S1
Johansson, LH1
Persson, H1
Rosengren, E1
Numata, H1
Suzuki, S1
Miyashita, A1
Suzuki, M1
Okubo, T1
Ajisawa, Y2
Yoneyama, T1
Yono, M1
Yoshida, M1
Takahashi, W1
Inadome, A1
Seshita, H1
Miyamoto, Y1
Ueda, S1
Small, RC1
Chiu, P1
Cook, SJ1
Foster, RW1
Isaac, L1
Komatsu, Y1
Kikkawa, H1
Naito, K1
Ikezawa, K1
Doggrell, SA2
Fujiwara, T1
Sumimoto, K1
Itoh, T1
Suzuki, H1
Kuriyama, H1
Ikezono, K1
Zerkowski, HR1
Beckeringh, JJ1
Michel, MC1
Brodde, OE1
Hedlund, H1
Andersson, KE1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Controlled,14-Treatment Day, Multicenter Study to Determine the Optimal Efficacious and Safe Dose of CHF 4226 in a Metered Dose Inhaler in Treating Patients With Chronic Obstructive Pulmonary Disease[NCT00605891]Phase 2278 participants (Actual)Interventional2006-10-31Completed
Evaluation of the Effect of 2 Weeks Treatment With CHF 4226 pMDI 2µg and 4µg, Given Once Daily in the Morning, on 24-Hour FEV1 in Patients With COPD[NCT00640484]Phase 257 participants (Actual)Interventional2008-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

16 other studies available for procaterol and Muscle Relaxation

ArticleYear
Functional and molecular characterization of beta-adrenoceptors in the internal anal sphincter.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anal Canal; Animals; Blotting, Western; In Vi

2003
Functional characterization of beta-adrenoceptor subtypes in the canine and rat lower urinary tract.
    The Journal of urology, 2003, Volume: 170, Issue:2 Pt 1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dioxoles; Dobutamine; Dogs; Female;

2003
Role of adenylate and guanylate cyclases in beta1-, beta2-, and beta3-adrenoceptor-mediated relaxation of internal anal sphincter smooth muscle.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 308, Issue:3

    Topics: Adenine; Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blotting

2004
Relaxant effects of beta-adrenergic agonists on porcine and human detrusor muscle.
    Acta physiologica Scandinavica, 2005, Volume: 185, Issue:2

    Topics: Adrenergic beta-Agonists; Aged; Albuterol; Animals; Dioxoles; Dose-Response Relationship, Drug; Epin

2005
Is there any evidence of beta 1-adrenoceptors mediating relaxation of guinea-pig lung parenchyma?
    Acta pharmacologica et toxicologica, 1984, Volume: 54, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Ethanolamines; Guinea Pigs; In Vitro Techniques; Isoproterenol

1984
Effects of beta 2-agonists on the contractility of fatigued canine diaphragm in vivo.
    Respiration physiology, 1993, Volume: 94, Issue:1

    Topics: Adrenergic beta-Agonists; Albuterol; Animals; Blood Pressure; Clenbuterol; Diaphragm; Dogs; Dose-Res

1993
Possible beta 3-adrenoceptor-mediated relaxation of the human detrusor.
    Acta physiologica Scandinavica, 1998, Volume: 164, Issue:1

    Topics: Adrenergic Antagonists; Adrenergic beta-Agonists; Adult; Aged; Bupranolol; Dobutamine; Dose-Response

1998
Effects of ovarian hormones on beta-adrenergic receptor-mediated relaxation in the female rabbit bladder.
    Urological research, 2000, Volume: 28, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Carbachol; Dobutamine; Estrogens; Female; Isoproterenol; Muscle R

2000
Beta-adrenoceptor agonists in bronchial asthma: role of k+-channel opening in mediating their bronchodilator effects.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1993, Volume: 23, Issue:10

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Anta

1993
Characterization of beta-adrenoceptor subtypes in the ferret urinary bladder in vitro and in vivo.
    European journal of pharmacology, 2000, Sep-01, Volume: 403, Issue:1-2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Blood Pressure; Dioxoles

2000
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
    Japanese journal of pharmacology, 1991, Volume: 57, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila

1991
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
    Japanese journal of pharmacology, 1991, Volume: 57, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila

1991
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
    Japanese journal of pharmacology, 1991, Volume: 57, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila

1991
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
    Japanese journal of pharmacology, 1991, Volume: 57, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila

1991
The effects of (+/-)-, (+)- and (-)-celiprolol and bromoacetylalprenololmentane at the beta-adrenoceptors of rat isolated cardiovascular preparations.
    The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:5

    Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Celiprolol; Electric Stimulation; Ethanolamines; H

1990
Relaxant and beta 2-adrenoceptor blocking activities of (+/- )-, (+)- and (-)-pindolol on the rat isolated aorta.
    The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Ethanolamines; In Vitro Techniques; Male; Mus

1990
Relaxing actions of procaterol, a beta 2-adrenoceptor stimulant, on smooth muscle cells of the dog trachea.
    British journal of pharmacology, 1988, Volume: 93, Issue:1

    Topics: Adrenergic beta-Agonists; Animals; Calcium; Cyclic AMP; Cytosol; Dogs; Drug Interactions; Ethanolami

1988
Beta-2 adrenoceptor-mediated relaxation of the isolated human saphenous vein.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1

    Topics: Bisoprolol; Ethanolamines; Female; Humans; In Vitro Techniques; Male; Mathematics; Muscle Relaxation

1987
Comparison of the responses to drugs acting on adrenoreceptors and muscarinic receptors in human isolated corpus cavernosum and cavernous artery.
    Journal of autonomic pharmacology, 1985, Volume: 5, Issue:1

    Topics: Acetylcholine; Aged; Carbachol; Clonidine; Electric Stimulation; Ethanolamines; Humans; In Vitro Tec

1985