procaterol has been researched along with Muscle Contraction in 21 studies
Procaterol: A long-acting beta-2-adrenergic receptor agonist.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Conversely, the IAS smooth muscle relaxation caused by beta(1)- and beta(2)-AR agonists (xamoterol and procaterol, respectively) was selectively antagonized by their respective antagonists CGP 20712 [(+/-)-2-hydroxy-5-[2-[[2-hydroxy-3-[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenoxy]propyl]amino]ethoxy]-benzamide methanesulfonate salt] and ICI 118551." | 3.72 | Functional and molecular characterization of beta-adrenoceptors in the internal anal sphincter. ( Banwait, K; Kazerounian, S; Rathi, S; Rattan, S; Schulz, S; Waldman, SA, 2003) |
| "We examined the effects of four beta 2-agonists, clenbuterol, metaproterenol, procaterol, and albuterol, on the contractility of fatigued canine diaphragm." | 3.68 | Effects of beta 2-agonists on the contractility of fatigued canine diaphragm in vivo. ( Miyashita, A; Numata, H; Okubo, T; Suzuki, M; Suzuki, S, 1993) |
| " There was a decrease in sensitivity to isoproterenol in spontaneously beating right atria, electrically driven left atria and field-stimulated vas deferens associated with hypothyroidism, with no change in maximum response." | 3.67 | Thyroid status and adrenergic receptor subtypes in the rat: comparison of receptor density and responsiveness. ( Abel, PW; Fox, AW; Johnson, RD; Juberg, EN; May, JM; Minneman, KP, 1985) |
| "6 Procaterol appears to be a particularly useful drug for detecting a functional population of beta 2-adrenoceptors in tissues, whether they are the minor or the predominant receptor sub-type present." | 1.27 | Responses to the beta 2-selective agonist procaterol of vascular and atrial preparations with different functional beta-adrenoceptor populations. ( O'Donnell, SR; Wanstall, JC, 1985) |
| "Prazosin was 300 times more active than rauwolscine in inhibiting NA-induced contractions." | 1.27 | Comparison of the responses to drugs acting on adrenoreceptors and muscarinic receptors in human isolated corpus cavernosum and cavernous artery. ( Andersson, KE; Hedlund, H, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (33.33) | 18.7374 |
| 1990's | 7 (33.33) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tamura, Y | 1 |
| Yoshizaki, S | 1 |
| Watanabe, K | 1 |
| Matsumoto, R | 1 |
| Otsuka, A | 1 |
| Suzuki, T | 1 |
| Shinbo, H | 1 |
| Mizuno, T | 1 |
| Kurita, Y | 1 |
| Mugiya, S | 1 |
| Ozono, S | 1 |
| Rathi, S | 1 |
| Kazerounian, S | 1 |
| Banwait, K | 1 |
| Schulz, S | 1 |
| Waldman, SA | 1 |
| Rattan, S | 1 |
| Takeda, H | 1 |
| Matsuzawa, A | 1 |
| Igawa, Y | 1 |
| Yamazaki, Y | 1 |
| Kaidoh, K | 1 |
| Akahane, S | 1 |
| Kojima, M | 1 |
| Miyata, H | 1 |
| Akahane, M | 1 |
| Nishizawa, O | 1 |
| Uzuki, M | 1 |
| Yamakage, M | 1 |
| Fujimura, N | 1 |
| Namiki, A | 1 |
| Ishimura, M | 1 |
| Kataoka, S | 1 |
| Suda, M | 1 |
| Maeda, T | 1 |
| Hiyama, Y | 1 |
| Shindoh, C | 1 |
| Sasaki, K | 1 |
| Shindoh, Y | 1 |
| Tamura, G | 1 |
| Johansson, LH | 1 |
| Persson, H | 1 |
| Rosengren, E | 1 |
| Numata, H | 1 |
| Suzuki, S | 1 |
| Miyashita, A | 1 |
| Suzuki, M | 1 |
| Okubo, T | 1 |
| Cook, SJ | 1 |
| Small, RC | 1 |
| Berry, JL | 1 |
| Chiu, P | 1 |
| Downing, SJ | 1 |
| Foster, RW | 1 |
| Carcano, R | 1 |
| Belloli, C | 1 |
| Arioli, F | 1 |
| Beretta, C | 1 |
| Mizutani, H | 1 |
| Kume, H | 1 |
| Ito, Y | 2 |
| Takagi, K | 1 |
| Yamaki, K | 1 |
| Aikawa, T | 1 |
| Sekizawa, K | 1 |
| Morikawa, M | 1 |
| Itabashi, S | 1 |
| Sasaki, H | 1 |
| Takishima, T | 1 |
| Aizawa, H | 1 |
| Inoue, H | 1 |
| Ikeda, T | 1 |
| Hirose, T | 1 |
| Kikkawa, H | 1 |
| Naito, K | 1 |
| Ikezawa, K | 1 |
| Watanabe-Kohno, S | 1 |
| Shimizu, T | 1 |
| Mizuta, J | 1 |
| Ogino, K | 1 |
| Yamamura, H | 1 |
| Ohata, K | 1 |
| O'Donnell, SR | 1 |
| Wanstall, JC | 1 |
| Waldeck, B | 1 |
| Jeppsson, AB | 1 |
| Widmark, E | 1 |
| Fujiwara, T | 1 |
| Sumimoto, K | 1 |
| Itoh, T | 1 |
| Suzuki, H | 1 |
| Kuriyama, H | 1 |
| Fox, AW | 1 |
| Juberg, EN | 1 |
| May, JM | 1 |
| Johnson, RD | 1 |
| Abel, PW | 1 |
| Minneman, KP | 1 |
| Hedlund, H | 1 |
| Andersson, KE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Controlled,14-Treatment Day, Multicenter Study to Determine the Optimal Efficacious and Safe Dose of CHF 4226 in a Metered Dose Inhaler in Treating Patients With Chronic Obstructive Pulmonary Disease[NCT00605891] | Phase 2 | 278 participants (Actual) | Interventional | 2006-10-31 | Completed | ||
| Evaluation of the Effect of 2 Weeks Treatment With CHF 4226 pMDI 2µg and 4µg, Given Once Daily in the Morning, on 24-Hour FEV1 in Patients With COPD[NCT00640484] | Phase 2 | 57 participants (Actual) | Interventional | 2008-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
21 other studies available for procaterol and Muscle Contraction
| Article | Year |
|---|---|
erythro-5-[1-Hydroxy-2-(isopropylamino)butyl]-7-hydroxycarbostyril, a terbutaline-type derivative of the bronchodilator procaterol.
Topics: Animals; Bronchodilator Agents; Chemical Phenomena; Chemistry; Ethanolamines; Guinea Pigs; In Vitro | 1981 |
Expression and functional role of β3 -adrenoceptors in the human ureter.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Aged; Aged, 80 and over; Albuterol; E | 2013 |
Functional and molecular characterization of beta-adrenoceptors in the internal anal sphincter.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anal Canal; Animals; Blotting, Western; In Vi | 2003 |
Functional characterization of beta-adrenoceptor subtypes in the canine and rat lower urinary tract.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dioxoles; Dobutamine; Dogs; Female; | 2003 |
Preferable inotropic action of procaterol, a potent bronchodilator, on impaired diaphragmatic contractility in an intraabdominal septic model.
Topics: Adrenergic beta-Antagonists; Animals; Bronchodilator Agents; Cyclic AMP; Diaphragm; In Vitro Techniq | 2006 |
Effects of KP-496, a novel dual antagonist for leukotriene D4 and thromboxane A2 receptors, on contractions induced by various agonists in the guinea pig trachea.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetates; Acetylcholine; Albuter | 2006 |
Inhalation and incubation with procaterol increases diaphragm muscle contractility in mice.
Topics: Administration, Inhalation; Adrenergic beta-Agonists; Animals; Diaphragm; Disease Models, Animal; En | 2007 |
Is there any evidence of beta 1-adrenoceptors mediating relaxation of guinea-pig lung parenchyma?
Topics: Adrenergic beta-Antagonists; Animals; Ethanolamines; Guinea Pigs; In Vitro Techniques; Isoproterenol | 1984 |
Effects of beta 2-agonists on the contractility of fatigued canine diaphragm in vivo.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Blood Pressure; Clenbuterol; Diaphragm; Dogs; Dose-Res | 1993 |
Beta-adrenoceptor subtypes and the opening of plasmalemmal K(+)-channels in trachealis muscle: electrophysiological and mechanical studies in guinea-pig tissue.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Benzopyrans; Cell Membran | 1993 |
Suitability of the old fowl rectal caecum preparation for investigating the selectivity of beta-adrenergic drugs.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Cecum; Chickens; Clenbuterol; Dobutami | 1998 |
Different effects of beta-adrenoceptor desensitization on inhibitory actions in guinea-pig trachealis.
Topics: Adrenergic beta-Agonists; Animals; Colforsin; Dose-Response Relationship, Drug; Guinea Pigs; In Vitr | 2002 |
The role of cyclic AMP in non-adrenergic non-cholinergic contraction in guinea-pig bronchi.
Topics: Animals; Autonomic Nervous System; Benzopyrans; Bronchi; Bronchodilator Agents; Bucladesine; Colfors | 1992 |
Effects of procaterol, a beta-2-adrenoceptor stimulant, on neuroeffector transmission in human bronchial tissue.
Topics: Acetylcholine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Bronchi; Ethanolamines; Female | 1991 |
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila | 1991 |
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila | 1991 |
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila | 1991 |
Tracheal relaxing effects and beta 2-selectivity of TA-2005, a newly developed bronchodilating agent, in isolated guinea pig tissues.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Amphetamines; Animals; Bronchodila | 1991 |
Effect of procaterol on the isolated airway smooth muscle and the release of anaphylactic chemical mediators from the isolated lung fragments.
Topics: Albuterol; Anaphylaxis; Animals; Bronchi; Ethanolamines; Guinea Pigs; Histamine Release; Humans; Hyp | 1990 |
Responses to the beta 2-selective agonist procaterol of vascular and atrial preparations with different functional beta-adrenoceptor populations.
Topics: Adrenergic beta-Agonists; Animals; Aorta; Atenolol; Coronary Vessels; Ethanolamines; Female; Fenoter | 1985 |
Partial agonism and functional selectivity: a study on beta-adrenoceptor mediated effects in tracheal, cardiac and skeletal muscle.
Topics: Adrenergic beta-Agonists; Animals; Benzyl Alcohols; Bronchodilator Agents; Carbachol; Ethanolamines; | 1986 |
Relaxing actions of procaterol, a beta 2-adrenoceptor stimulant, on smooth muscle cells of the dog trachea.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Cyclic AMP; Cytosol; Dogs; Drug Interactions; Ethanolami | 1988 |
Thyroid status and adrenergic receptor subtypes in the rat: comparison of receptor density and responsiveness.
Topics: Animals; Cerebral Cortex; Ethanolamines; Heart; Heart Rate; Hyperthyroidism; Hypothyroidism; In Vitr | 1985 |
Comparison of the responses to drugs acting on adrenoreceptors and muscarinic receptors in human isolated corpus cavernosum and cavernous artery.
Topics: Acetylcholine; Aged; Carbachol; Clonidine; Electric Stimulation; Ethanolamines; Humans; In Vitro Tec | 1985 |