procaterol has been researched along with Cough in 9 studies
Procaterol: A long-acting beta-2-adrenergic receptor agonist.
Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Procaterol, a selective, short-acting beta-2 adrenoceptor agonist, is effective in treating 'classical' asthma, but its efficacy for cough-variant asthma (CVA) is unknown." | 9.17 | Efficacy of procaterol combined with inhaled budesonide for treatment of cough-variant asthma. ( Bao, W; Chen, Q; Chen, Z; Lin, Y; Liu, H; Zhao, G; Zhou, X, 2013) |
| "To evaluate the effect of inhaled beta 2 adrenergic agonists on the sensitivity of airway cough receptors, the effect of inhaled procaterol on cough induced by aerosolised capsaicin, a stimulant of C fibres, was studied in patients with asthma or chronic bronchitis and in normal subjects." | 9.07 | Effect of inhaled procaterol on cough receptor sensitivity to capsaicin in patients with asthma or chronic bronchitis and in normal subjects. ( Bando, T; Fujimura, M; Kamio, Y; Kurashima, K; Matsuda, T; Sakamoto, S, 1993) |
| "The threshold of the cough response to inhaled capsaicin, a stimulant acting on C fibre endings, and tartaric acid, a chemostimulant, was measured before and 10 minutes after inhalation of methacholine, which caused a nearly 20% fall in forced expiratory volume in one second (FEV1), in 14 normal subjects (study 1), and also before and 30 minutes after inhalation of procaterol (30 micrograms), placebo, and saline in eight normal subjects (study 2)." | 9.07 | Effects of methacholine induced bronchoconstriction and procaterol induced bronchodilation on cough receptor sensitivity to inhaled capsaicin and tartaric acid. ( Fujimura, M; Kamio, Y; Matsuda, T; Sakamoto, S, 1992) |
| "To examine the role of substance P (SP) in cough during bronchoconstriction, we studied the effects of an aerosolized beta-adrenoceptor agonist, procaterol, and a specific inhibitor of SP (NK1) receptor, FK 888, on bronchoconstriction and cough induced by aerosols of histamine and acetylcholine (ACh) in unsensitized guinea pigs and by those of ovalbumin (OA) antigen in guinea pigs sensitized to OA." | 7.69 | Role of substance P in cough during bronchoconstriction in awake guinea pigs. ( Ebihara, T; Sasaki, H; Sekizawa, K, 1995) |
| "To examine the mechanisms of an angiotensin-converting enzyme (ACE) inhibitor-induced cough in perimenopausal and postmenopausal women, cough responses to aerosols of capsaicin and citric acid were examined in four groups of female guinea pigs treated orally with danazol (D) (an agent decreasing plasma estrogen levels), cilazapril (C) (an inhibitor of ACE), both danazol and cilazapril (C+D), or without either drug (control group) for 4 to 5 wk." | 7.69 | Angiotensin-converting enzyme inhibitor and danazol increase sensitivity of cough reflex in female guinea pigs. ( Ebihara, T; Nakazawa, H; Ohrui, T; Sasaki, H; Sekizawa, K, 1996) |
| "We studied substance P (SP)-induced cough in normal subjects without and with colds, and the effects of orally administered procaterol on SP-induced cough in normal subjects with colds." | 7.67 | Inhibitory actions of procaterol, a beta-2 stimulant, on substance P-induced cough in normal subjects during upper respiratory tract infection. ( Inoue, H; Katsumata, U; Sasaki, H; Sekizawa, K; Takishima, T, 1989) |
| "Procaterol, a selective, short-acting beta-2 adrenoceptor agonist, is effective in treating 'classical' asthma, but its efficacy for cough-variant asthma (CVA) is unknown." | 5.17 | Efficacy of procaterol combined with inhaled budesonide for treatment of cough-variant asthma. ( Bao, W; Chen, Q; Chen, Z; Lin, Y; Liu, H; Zhao, G; Zhou, X, 2013) |
| "To evaluate the effect of inhaled beta 2 adrenergic agonists on the sensitivity of airway cough receptors, the effect of inhaled procaterol on cough induced by aerosolised capsaicin, a stimulant of C fibres, was studied in patients with asthma or chronic bronchitis and in normal subjects." | 5.07 | Effect of inhaled procaterol on cough receptor sensitivity to capsaicin in patients with asthma or chronic bronchitis and in normal subjects. ( Bando, T; Fujimura, M; Kamio, Y; Kurashima, K; Matsuda, T; Sakamoto, S, 1993) |
| "The threshold of the cough response to inhaled capsaicin, a stimulant acting on C fibre endings, and tartaric acid, a chemostimulant, was measured before and 10 minutes after inhalation of methacholine, which caused a nearly 20% fall in forced expiratory volume in one second (FEV1), in 14 normal subjects (study 1), and also before and 30 minutes after inhalation of procaterol (30 micrograms), placebo, and saline in eight normal subjects (study 2)." | 5.07 | Effects of methacholine induced bronchoconstriction and procaterol induced bronchodilation on cough receptor sensitivity to inhaled capsaicin and tartaric acid. ( Fujimura, M; Kamio, Y; Matsuda, T; Sakamoto, S, 1992) |
| "To examine the role of substance P (SP) in cough during bronchoconstriction, we studied the effects of an aerosolized beta-adrenoceptor agonist, procaterol, and a specific inhibitor of SP (NK1) receptor, FK 888, on bronchoconstriction and cough induced by aerosols of histamine and acetylcholine (ACh) in unsensitized guinea pigs and by those of ovalbumin (OA) antigen in guinea pigs sensitized to OA." | 3.69 | Role of substance P in cough during bronchoconstriction in awake guinea pigs. ( Ebihara, T; Sasaki, H; Sekizawa, K, 1995) |
| "To examine the mechanisms of an angiotensin-converting enzyme (ACE) inhibitor-induced cough in perimenopausal and postmenopausal women, cough responses to aerosols of capsaicin and citric acid were examined in four groups of female guinea pigs treated orally with danazol (D) (an agent decreasing plasma estrogen levels), cilazapril (C) (an inhibitor of ACE), both danazol and cilazapril (C+D), or without either drug (control group) for 4 to 5 wk." | 3.69 | Angiotensin-converting enzyme inhibitor and danazol increase sensitivity of cough reflex in female guinea pigs. ( Ebihara, T; Nakazawa, H; Ohrui, T; Sasaki, H; Sekizawa, K, 1996) |
| "We studied substance P (SP)-induced cough in normal subjects without and with colds, and the effects of orally administered procaterol on SP-induced cough in normal subjects with colds." | 3.67 | Inhibitory actions of procaterol, a beta-2 stimulant, on substance P-induced cough in normal subjects during upper respiratory tract infection. ( Inoue, H; Katsumata, U; Sasaki, H; Sekizawa, K; Takishima, T, 1989) |
| "The cough was relieved by inhaled procaterol in 10 patients (Group 2) but not in the other 10 patients (Group 1)." | 1.28 | Bronchodilator-resistive cough in atopic patients: bronchial reversibility and hyperresponsiveness. ( Fujimura, M; Matsuda, T; Sakamoto, S, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bao, W | 1 |
| Chen, Q | 1 |
| Lin, Y | 1 |
| Liu, H | 1 |
| Zhao, G | 1 |
| Chen, Z | 1 |
| Zhou, X | 1 |
| Ohkura, N | 1 |
| Fujimura, M | 5 |
| Hara, J | 1 |
| Ohsawa, M | 1 |
| Kamei, J | 1 |
| Nakao, S | 2 |
| Nishitsuji, M | 1 |
| Oribe, Y | 1 |
| Sekizawa, K | 3 |
| Ebihara, T | 2 |
| Sasaki, H | 3 |
| Sakamoto, S | 3 |
| Kamio, Y | 2 |
| Bando, T | 1 |
| Kurashima, K | 1 |
| Matsuda, T | 3 |
| Ohrui, T | 1 |
| Nakazawa, H | 1 |
| Katsumata, U | 1 |
| Inoue, H | 1 |
| Takishima, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Oral Procaterol on Chronic Persistent Cough Following Upper Respiratory Tract Infection: Double-Blind Randomized Placebo-Controlled Trial[NCT02349919] | 74 participants (Anticipated) | Interventional | 2015-03-31 | Recruiting | |||
| The Effects of Tiotropium on the Cough Reflex in Patients With COPD[NCT00870896] | Early Phase 1 | 5 participants (Actual) | Interventional | 2008-02-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Change in FEV1 ( in liters) at baseline and following 30 days of treatment with Spiriva (NCT00870896)
Timeframe: 30 days
| Intervention | liters (Mean) |
|---|---|
| Spirometry | .315 |
We measured the change in FEV1/FVC ratio at baseline and following 30 days of treatment with Spiriva.Change in ratio reflects the percentage value (ratio) at 30 days minus the percentage value (ratio) at baseline x 100 (NCT00870896)
Timeframe: 30 days
| Intervention | percentage change (Mean) |
|---|---|
| Change in FEV1/FVC | 3 |
We measured the change in the number of coughs following capsaicin inhalation challenge from baseline followed by 30 days of treatment with spiriva (NCT00870896)
Timeframe: 30 days
| Intervention | coughs per dose of capsaicin (Mean) |
|---|---|
| Group 1 | 2.5 |
3 trials available for procaterol and Cough
| Article | Year |
|---|---|
Efficacy of procaterol combined with inhaled budesonide for treatment of cough-variant asthma.
Topics: Adrenergic beta-2 Receptor Agonists; Adult; Asthma; Bronchodilator Agents; Budesonide; China; Comorb | 2013 |
Effect of inhaled procaterol on cough receptor sensitivity to capsaicin in patients with asthma or chronic bronchitis and in normal subjects.
Topics: Administration, Inhalation; Adult; Aged; Asthma; Bronchi; Bronchitis; Bronchoconstriction; Capsaicin | 1993 |
Effects of methacholine induced bronchoconstriction and procaterol induced bronchodilation on cough receptor sensitivity to inhaled capsaicin and tartaric acid.
Topics: Adult; Bronchi; Bronchoconstriction; Capsaicin; Cough; Ethanolamines; Female; Forced Expiratory Volu | 1992 |
6 other studies available for procaterol and Cough
| Article | Year |
|---|---|
Bronchoconstriction-triggered cough in conscious guinea pigs.
Topics: Administration, Inhalation; Animals; Bronchoconstriction; Capsaicin; Cough; Dose-Response Relationsh | 2009 |
A guinea pig model for cough variant asthma and role of tachykinins.
Topics: Airway Resistance; Allergens; Animals; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage F | 2004 |
Role of substance P in cough during bronchoconstriction in awake guinea pigs.
Topics: Animals; Bronchial Provocation Tests; Bronchoconstriction; Consciousness; Cough; Dipeptides; Dose-Re | 1995 |
Angiotensin-converting enzyme inhibitor and danazol increase sensitivity of cough reflex in female guinea pigs.
Topics: Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Capsaicin; Cilazapril; | 1996 |
Bronchodilator-resistive cough in atopic patients: bronchial reversibility and hyperresponsiveness.
Topics: Adrenergic beta-Agonists; Adult; Aged; Bronchi; Bronchodilator Agents; Cough; Drug Resistance; Ethan | 1992 |
Inhibitory actions of procaterol, a beta-2 stimulant, on substance P-induced cough in normal subjects during upper respiratory tract infection.
Topics: Adrenergic beta-Agonists; Adult; Cough; Ethanolamines; Female; Forced Expiratory Volume; Humans; Mal | 1989 |