procarbazine has been researched along with Vomiting in 15 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The severity of emesis is dependent on the dose of cyclophosphamide and on the addition of other cytotoxic drugs." | 2.39 | Optimal control of cyclophosphamide-induced emesis. ( Stewart, A, 1996) |
| "Seventy patients with advanced Hodgkin's disease, 54 with new disease, and 16 in first relapse after initial radiotherapy, have been treated with a seven-drug, 8-month program: MOPP (nitrogen mustard, vincristine, procarbazine, prednisone)/ABV (Adriamycin [Adria Laboratories of Canada, Mississauga, Ontario], bleomycin, vinblastine) hybrid." | 1.27 | MOPP/ABV hybrid program: combination chemotherapy based on early introduction of seven effective drugs for advanced Hodgkin's disease. ( Connors, JM; Klimo, P, 1985) |
| " A number of the toxic effects of procarbazine seen in humans were also noted in this series of monkeys, including vomiting and myelosuppression." | 1.26 | Carcinogenic and other adverse effects of procarbazine in nonhuman primates. ( Adamson, RH; Correa, P; Dalgard, DW; Sieber, SM, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (86.67) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Straus, DJ | 1 |
| Myers, J | 1 |
| Passe, S | 1 |
| Young, CW | 1 |
| Nisce, LZ | 1 |
| Lee, BJ | 1 |
| Koziner, B | 1 |
| Arlin, Z | 1 |
| Kempin, S | 1 |
| Gee, T | 1 |
| Clarkson, BD | 1 |
| Jurcic, JG | 1 |
| Koll, B | 1 |
| Brown, AE | 1 |
| Crown, JP | 1 |
| Yahalom, J | 1 |
| Gulati, SC | 1 |
| Stewart, A | 1 |
| Sieber, SM | 1 |
| Correa, P | 1 |
| Dalgard, DW | 1 |
| Adamson, RH | 1 |
| Benjamin, RS | 1 |
| Wiernik, PH | 1 |
| O'Connell, MJ | 1 |
| Chang, P | 1 |
| Sutherland, JC | 1 |
| Klener, P | 1 |
| Donner, L | 1 |
| Klimo, P | 1 |
| Connors, JM | 1 |
| Lowenthal, RM | 1 |
| Jestrimski, KW | 1 |
| Tummarello, D | 1 |
| Guidi, F | 1 |
| Porfiri, E | 1 |
| Isidori, P | 1 |
| Raspugli, M | 1 |
| Cellerino, R | 1 |
| Griffiths, JD | 1 |
| Hartwich, G | 1 |
| Varkarakis, MJ | 1 |
| Sampson, D | 1 |
| Brede, HD | 1 |
| Murphy, GP | 1 |
| Landgren, RC | 1 |
| Hussey, DH | 1 |
| Samuels, ML | 1 |
| Leary, WV | 1 |
| Mubashir, BA | 1 |
| Shullenberger, CC | 1 |
| Gamble, JF | 1 |
| Thumb, N | 1 |
| Gangl, A | 1 |
| Horak, W | 1 |
| Richter, H | 1 |
2 reviews available for procarbazine and Vomiting
| Article | Year |
|---|---|
Optimal control of cyclophosphamide-induced emesis.
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Epirubic | 1996 |
Corticosteroid drugs: their role in oncological practice.
Topics: Adrenal Cortex Hormones; Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast | 1986 |
2 trials available for procarbazine and Vomiting
| Article | Year |
|---|---|
The eight-drug/radiation therapy program (MOPP/ABDV/RT) for advanced Hodgkin's disease: a follow-up report.
Topics: Adolescent; Adult; Antineoplastic Agents; Bleomycin; Dacarbazine; Doxorubicin; Drug Administration S | 1980 |
A randomized study comparing irradiation alone to irradiation plus procarbazine in inoperable bronchogenic carcinoma.
Topics: Antineoplastic Agents; Benzoates; Carcinoma, Bronchogenic; Clinical Trials as Topic; Cobalt Isotopes | 1973 |
11 other studies available for procarbazine and Vomiting
| Article | Year |
|---|---|
Excretion of Ascaris lumbricoides during total body irradiation.
Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Ascariasis; Ascaris lumbricoides; Bo | 1994 |
Carcinogenic and other adverse effects of procarbazine in nonhuman primates.
Topics: Animals; Bone Marrow; Carcinogens; Cercopithecus; Female; Haplorhini; Leukemia, Experimental; Leukem | 1978 |
A comparison of cyclophosphamide, vincristine, and prednisone (COP) with nitrogen mustard, vincristine, procarbazine, and prednisone (MOPP) in the treatment of nodular, poorly differentiated, lymphocytic lymphoma.
Topics: Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Female; Humans; Lymphoma, Non-Hodgkin; Male; M | 1976 |
Trichlortriethylamine (TS-160 Spofa) in combination chemotherapy of malignant lymphomas.
Topics: Adult; Aged; Antineoplastic Agents; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Lymp | 1975 |
MOPP/ABV hybrid program: combination chemotherapy based on early introduction of seven effective drugs for advanced Hodgkin's disease.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomyc | 1985 |
Results of a combined chemo-radiotherapeutic program in 61 patients affected by small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Carcinoma, Small Cell; Cis | 1988 |
Mallory-Weiss tear and cytotoxic-induced emesis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Hodgkin Disease; Humans; Male; Mallory-Weiss | 1986 |
[Influencing of side-effects of cytostatic drugs using metoclopramide].
Topics: Amides; Anisoles; Antineoplastic Agents; Benzoates; Carcinoma; Ethylamines; Hodgkin Disease; Humans; | 1973 |
The immunosuppressive effect of procarbazine hydrochloride in canine renal allografts.
Topics: Administration, Oral; Animals; Benzoates; Diarrhea; Dogs; Immunosuppression Therapy; Immunosuppressi | 1972 |
Treatment of advanced Hodgkin's disease with combination chemotherapy.
Topics: Adult; Antineoplastic Agents; Dactinomycin; Drug Therapy, Combination; Female; Hodgkin Disease; Huma | 1973 |
[Experiences with the immunosuppressive treatment of rheumatoid arthritis].
Topics: Administration, Oral; Adult; Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine; Benzoates; | 1969 |