procarbazine has been researched along with Trypanosomiasis in 1 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Trypanosomiasis: Infection with protozoa of the genus TRYPANOSOMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methylating agents, such as streptozotocin, procarbazine, N-methyl-N-nitrosourea, dimethyl sulfate, 1,2-dimethylhydrazine, and a series of 1,2-bis(sulfonyl)-1-methylhydrazines synthesized in this laboratory, were evaluated and shown to be therapeutically active against murine models of African trypanosomiasis." | 3.68 | Methylating agents as trypanocides. ( Divo, AA; Patton, CL; Penketh, PG; Sartorelli, AC; Shyam, K, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Penketh, PG | 1 |
| Shyam, K | 1 |
| Divo, AA | 1 |
| Patton, CL | 1 |
| Sartorelli, AC | 1 |
1 other study available for procarbazine and Trypanosomiasis
| Article | Year |
|---|---|
Methylating agents as trypanocides.
Topics: Alkylating Agents; Animals; Methylation; Mice; Trypanocidal Agents; Trypanosoma brucei brucei; Trypa | 1990 |