Page last updated: 2024-11-03

procarbazine and Thymoma

procarbazine has been researched along with Thymoma in 6 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Thymoma: A neoplasm originating from thymic tissue, usually benign, and frequently encapsulated. Although it is occasionally invasive, metastases are extremely rare. It consists of any type of thymic epithelial cell as well as lymphocytes that are usually abundant. Malignant lymphomas that involve the thymus, e.g., lymphosarcoma, Hodgkin's disease (previously termed granulomatous thymoma), should not be regarded as thymoma. (From Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"Combination chemotherapy consisting of cyclophosphamide, vincristine, prednisone, and procarbazine (COPP) was administered to 5 patients with invasive lymphoepithelial thymoma."3.66Combination chemotherapy in invasive thymoma role of COPP. ( Evans, WK; Feld, R; Phillips, MJ; Simpson, WJ; Thompson, DM, 1980)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rajan, A1
Giaccone, G1
Evans, WK1
Thompson, DM1
Simpson, WJ1
Feld, R1
Phillips, MJ1
Agrawal, S1
Datta, NR1
Mishra, SK1
Kumar, S1
Tandon, V1
Ayyagari, S1
Agarwal, A1
Boston, B1
Ramon, P1
Wallaert, B1
Lemaître, L1
Fournier, E1
Rémy, J1
Bart, F1
Gosselin, B1
Tonnel, AB1
Göldel, N1
Böning, L1
Fredrik, A1
Hölzel, D1
Hartenstein, R1
Wilmanns, W1

Reviews

1 review available for procarbazine and Thymoma

ArticleYear
Chemotherapy for thymic tumors: induction, consolidation, palliation.
    Thoracic surgery clinics, 2011, Volume: 21, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cisplatin; Clinical Trials as Topic; C

2011

Other Studies

5 other studies available for procarbazine and Thymoma

ArticleYear
Combination chemotherapy in invasive thymoma role of COPP.
    Cancer, 1980, Oct-01, Volume: 46, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Co

1980
Adjuvant therapy in invasive thymoma: an audit of cases treated over an 8 year period.
    Indian journal of cancer, 1999, Volume: 36, Issue:1

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; An

1999
Chemotherapy of invasive thymoma.
    Cancer, 1976, Volume: 38, Issue:1

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Antineoplastic Agents; Cisplatin; Doxorubicin; Drug

1976
[Value of x-ray computed tomography in assessing the extent of invasive lympho-epithelial thymoma in the adult. Therapeutic implications].
    Revue des maladies respiratoires, 1986, Volume: 3, Issue:2

    Topics: Adrenal Cortex Neoplasms; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined

1986
Chemotherapy of invasive thymoma. A retrospective study of 22 cases.
    Cancer, 1989, Apr-15, Volume: 63, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality

1989