Page last updated: 2024-11-03

procarbazine and T-Cell Lymphoma

procarbazine has been researched along with T-Cell Lymphoma in 9 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Research Excerpts

ExcerptRelevanceReference
"To describe the clinical course of patients with angioimmunoblastic lymphadenopathy (AILD)-type lymphoma with a sequential treatment with prednisone and COPBLAM/IMVP-16."9.07Treatment of angioimmunoblastic lymphadenopathy (AILD)-type T-cell lymphoma using prednisone with or without the COPBLAM/IMVP-16 regimen. A multicenter study. Kiel Lymphoma Study Group. ( Agthe, A; Brittinger, G; Engelhard, M; Griesser, H; Huhn, D; Kuse, R; Lennert, K; Schwerdtfeger, R; Siegert, W; Tiemann, M, 1992)
"Lomustine, vincristine, procarbazine and prednisolone (LOPP) chemotherapy has been suggested to be an effective treatment for dogs with naïve non-indolent T-cell lymphoma (TCL)."8.12Prognostic indicators for naïve canine non-indolent T-cell lymphoma treated with combination lomustine, vincristine, procarbazine and prednisolone chemotherapy. ( Blaxill, J; Buzzacott, P; Finlay, J, 2022)
"To describe the clinical course of patients with angioimmunoblastic lymphadenopathy (AILD)-type lymphoma with a sequential treatment with prednisone and COPBLAM/IMVP-16."5.07Treatment of angioimmunoblastic lymphadenopathy (AILD)-type T-cell lymphoma using prednisone with or without the COPBLAM/IMVP-16 regimen. A multicenter study. Kiel Lymphoma Study Group. ( Agthe, A; Brittinger, G; Engelhard, M; Griesser, H; Huhn, D; Kuse, R; Lennert, K; Schwerdtfeger, R; Siegert, W; Tiemann, M, 1992)
"Lomustine, vincristine, procarbazine and prednisolone (LOPP) chemotherapy has been suggested to be an effective treatment for dogs with naïve non-indolent T-cell lymphoma (TCL)."4.12Prognostic indicators for naïve canine non-indolent T-cell lymphoma treated with combination lomustine, vincristine, procarbazine and prednisolone chemotherapy. ( Blaxill, J; Buzzacott, P; Finlay, J, 2022)
"The aim of this study was to describe the use of a lomustine (CCNU), vincristine, procarbazine and prednisolone (LOPP) protocol used for treatment of chemotherapy naive T-cell lymphoma patients and to describe the response rate, toxicity and disease-free interval compared historically to CHOP chemotherapy."3.88LOPP chemotherapy as a first-line treatment for dogs with T-cell lymphoma. ( Brown, PM; Langova, V; Nguyen, S; Tzannes, S; White, J, 2018)
" Results of axillary lymph node, skin, and bone-marrow biopsies led to the diagnosis of angioimmunoblastic T-cell lymphoma (AITL), for which CEPP therapy (cyclophosphamide, etoposide, procarbazine, and prednisolone) was initiated."3.88Emergence of anti-mitochondrial M2 antibody in patient with angioimmunoblastic T-cell lymphoma. ( Hiroshima, Y; Joshita, S; Kawata, K; Kimura, T; Kobayashi, H; Mori, H; Tanaka, E; Tanaka, N; Umemura, T; Wada, S; Wakabayashi, SI, 2018)
"We report two patients who developed visual hallucinations during treatment with vincristine."1.29Visual hallucinations following treatment with vincristine. ( Chapman, CS; Ghosh, K; Murphy, P; Sivakumaran, M; Wood, JK, 1994)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (44.44)18.2507
2000's1 (11.11)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Blaxill, J1
Buzzacott, P1
Finlay, J1
Brown, PM1
Tzannes, S1
Nguyen, S1
White, J1
Langova, V1
Wakabayashi, SI1
Kimura, T1
Tanaka, N1
Joshita, S1
Kawata, K1
Umemura, T1
Hiroshima, Y1
Mori, H1
Kobayashi, H1
Wada, S1
Tanaka, E1
Morgan, E1
O'Connell, K1
Thomson, M1
Griffin, A1
Ghosh, K1
Sivakumaran, M1
Murphy, P1
Chapman, CS1
Wood, JK1
Rysenga, E1
Linden, MD1
Carey, JL1
Ross, CW1
Schnitzer, B1
Sawdyk, M1
Maeda, K1
Niitsu, N1
Iijima, K1
Chizuka, A1
Siegert, W1
Agthe, A1
Griesser, H1
Schwerdtfeger, R1
Brittinger, G1
Engelhard, M1
Kuse, R1
Tiemann, M1
Lennert, K1
Huhn, D1
Liang, R1
Chiu, E1
Chan, TK1
Todd, D1
Loke, SL1

Trials

1 trial available for procarbazine and T-Cell Lymphoma

ArticleYear
Treatment of angioimmunoblastic lymphadenopathy (AILD)-type T-cell lymphoma using prednisone with or without the COPBLAM/IMVP-16 regimen. A multicenter study. Kiel Lymphoma Study Group.
    Annals of internal medicine, 1992, Sep-01, Volume: 117, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophos

1992

Other Studies

8 other studies available for procarbazine and T-Cell Lymphoma

ArticleYear
Prognostic indicators for naïve canine non-indolent T-cell lymphoma treated with combination lomustine, vincristine, procarbazine and prednisolone chemotherapy.
    Veterinary and comparative oncology, 2022, Volume: 20, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Dog Diseases; Dogs; Hypercalcemia; Lomustin

2022
LOPP chemotherapy as a first-line treatment for dogs with T-cell lymphoma.
    Veterinary and comparative oncology, 2018, Volume: 16, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Dog Diseases; Dogs; Female; Lomustine; Lymp

2018
Emergence of anti-mitochondrial M2 antibody in patient with angioimmunoblastic T-cell lymphoma.
    Clinical journal of gastroenterology, 2018, Volume: 11, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Cyclophosphamide; Etoposide; F

2018
Canine T cell lymphoma treated with lomustine, vincristine, procarbazine, and prednisolone chemotherapy in 35 dogs.
    Veterinary and comparative oncology, 2018, Volume: 16, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Dog Diseases; Dogs;

2018
Visual hallucinations following treatment with vincristine.
    Clinical and laboratory haematology, 1994, Volume: 16, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carmustine; Cyclophosphamide; Doxorubicin

1994
Peripheral T-cell non-Hodgkin's lymphoma following treatment of nodular lymphocyte predominance Hodgkin's disease.
    Archives of pathology & laboratory medicine, 1995, Volume: 119, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Hodgkin Disease; Humans; Lymphocytes; Lymphoma, B-Ce

1995
A high serum-soluble interleukin-2 receptor level is associated with a poor outcome of aggressive non-Hodgkin's lymphoma.
    European journal of haematology, 2001, Volume: 66, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomyci

2001
Direct comparison of peripheral T-cell lymphomas with their B-cell counterpart.
    Acta haematologica, 1991, Volume: 85, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; China; Cyclophosphamide; Dexamethasone; D

1991