procarbazine has been researched along with Stevens-Johnson Syndrome in 2 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hodgkin's disease has been associated with a variety of cutaneous symptoms." | 1.40 | [Stevens-Johnson syndrome and Hodgkin's disease: A fortuitous association or paraneoplastic syndrome?]. ( Barbaud, A; Bursztejn, AC; Cribier, B; Cuny, JF; Levy, E; Schmutz, JL; Schoeffler, A; Weinborn, M, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schoeffler, A | 1 |
| Levy, E | 1 |
| Weinborn, M | 1 |
| Cuny, JF | 1 |
| Schmutz, JL | 1 |
| Barbaud, A | 1 |
| Cribier, B | 1 |
| Bursztejn, AC | 1 |
| Jones, R | 1 |
| Kirkup, M | 1 |
| Guglani, S | 1 |
| Hopkins, K | 1 |
2 other studies available for procarbazine and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
[Stevens-Johnson syndrome and Hodgkin's disease: A fortuitous association or paraneoplastic syndrome?].
Topics: Adrenal Cortex Hormones; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Causality | 2014 |
Toxic epidermal necrolysis after PCV combination chemotherapy for relapsed B-cell lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Humans; Lomustine; Lymphoma, B-Cell | 2006 |