procarbazine has been researched along with Sterility, Male in 19 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three patients with remission of Hodgkin's disease after involved-field (two) and extended-field (one) radiotherapy died from cardiovascular disease that could only be attributed to the prior radiotherapy." | 2.66 | Treatment of stages I and II Hodgkin's disease with three different therapeutic modalities. ( Caravelli, J; Cirrincione, C; Cunningham, I; Koziner, B; McCormick, B; Mertelsmann, R; Myers, J; Nisce, LZ; Redman, J; Straus, DJ, 1986) |
| "A questionnaire was sent to 180 Hodgkin lymphoma (HL) patients." | 1.43 | Fertility in young patients following treatment for Hodgkin's lymphoma: a single center survey. ( Boltežar, L; Jezeršek Novaković, B; Pintarić, K, 2016) |
| "We followed-up 33 patients with non-Hodgkin's lymphoma or with Hodgkin's disease during the years 1987-1997 who were referred for semen cryopreservation." | 1.31 | Follow-up of sperm concentration and motility in patients with lymphoma. ( Botchan, A; Hauser, R; Paz, G; Tal, R; Yavetz, H; Yogev, L, 2000) |
| "The effects of chronic administration of cyclophosphamide and procarbazine on testicular function in the rat were examined." | 1.27 | A rat model for chemotherapy-induced male infertility. ( Glode, LM; Gould, SF; Nett, T; Powell, D, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (42.11) | 18.7374 |
| 1990's | 7 (36.84) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Amin, MSA | 1 |
| Brunckhorst, O | 1 |
| Scott, C | 1 |
| Wrench, D | 1 |
| Gleeson, M | 1 |
| Kazmi, M | 1 |
| Ahmed, K | 1 |
| Boltežar, L | 1 |
| Pintarić, K | 1 |
| Jezeršek Novaković, B | 1 |
| Paoli, D | 1 |
| Rizzo, F | 1 |
| Fiore, G | 1 |
| Pallotti, F | 1 |
| Pulsoni, A | 1 |
| Annechini, G | 1 |
| Lombardo, F | 1 |
| Lenzi, A | 1 |
| Gandini, L | 1 |
| Bonadonna, G | 1 |
| Santoro, A | 1 |
| Viviani, S | 1 |
| Lombardi, C | 1 |
| Ragni, G | 1 |
| Dein, RA | 1 |
| Mennuti, MT | 1 |
| Kovach, P | 1 |
| Gabbe, SG | 1 |
| Gould, SF | 1 |
| Powell, D | 1 |
| Nett, T | 1 |
| Glode, LM | 1 |
| Weissenberg, R | 1 |
| Lahav, M | 1 |
| Raanani, P | 1 |
| Singer, R | 1 |
| Regev, A | 1 |
| Sagiv, M | 1 |
| Giler, S | 1 |
| Theodor, E | 1 |
| Shafford, EA | 1 |
| Kingston, JE | 1 |
| Malpas, JS | 2 |
| Plowman, PN | 1 |
| Pritchard, J | 1 |
| Savage, MO | 1 |
| Eden, OB | 1 |
| Morris, ID | 1 |
| Meistrich, ML | 2 |
| Wilson, G | 2 |
| Zhang, Y | 1 |
| Kurdoglu, B | 1 |
| Terry, NH | 1 |
| Huhtaniemi, I | 1 |
| Tal, R | 1 |
| Botchan, A | 1 |
| Hauser, R | 1 |
| Yogev, L | 1 |
| Paz, G | 1 |
| Yavetz, H | 1 |
| Schein, PS | 1 |
| Winokur, SH | 1 |
| Chapman, RM | 1 |
| Sutcliffe, SB | 1 |
| Rees, LH | 1 |
| Edwards, CR | 1 |
| Amiel, JL | 1 |
| Droz, JP | 1 |
| Tursz, T | 1 |
| Charak, BS | 1 |
| Gupta, R | 1 |
| Mandrekar, P | 1 |
| Sheth, NA | 1 |
| Banavali, SD | 1 |
| Saikia, TK | 1 |
| Gopal, R | 1 |
| Dinshaw, KA | 1 |
| Advani, SH | 1 |
| Velez de la Calle, JF | 1 |
| Jégou, B | 1 |
| Koziner, B | 1 |
| Myers, J | 1 |
| Cirrincione, C | 1 |
| Redman, J | 1 |
| Cunningham, I | 1 |
| Caravelli, J | 1 |
| Nisce, LZ | 1 |
| McCormick, B | 1 |
| Straus, DJ | 1 |
| Mertelsmann, R | 1 |
| Arseneau, JC | 1 |
| Canellos, GP | 1 |
| DeVita, VT | 1 |
| Sherins, RJ | 1 |
5 reviews available for procarbazine and Sterility, Male
| Article | Year |
|---|---|
ABVD and BEACOPP regimens' effects on fertility in young males with Hodgkin lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dacarbazine; Doxorubici | 2021 |
The reproductive potential of young men and women with Hodgkin's disease.
Topics: Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Congenital Abnormalities; Female; | 1984 |
Protection against cytotoxic-induced testis damage--experimental approaches.
Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Humans; Infertility, Male; Male; Procarbazin | 1993 |
Immunosuppressive and cytotoxic chemotherapy: long-term complications.
Topics: Alkylating Agents; Antineoplastic Agents; Azathioprine; Bleomycin; Busulfan; Carcinogens; Chemical a | 1975 |
Recently recognized complications of cancer chemotherapy.
Topics: Antineoplastic Agents; Burkitt Lymphoma; Cyclophosphamide; Death, Sudden; Drug Therapy, Combination; | 1974 |
1 trial available for procarbazine and Sterility, Male
| Article | Year |
|---|---|
Treatment of stages I and II Hodgkin's disease with three different therapeutic modalities.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Hodgkin Di | 1986 |
13 other studies available for procarbazine and Sterility, Male
| Article | Year |
|---|---|
Fertility in young patients following treatment for Hodgkin's lymphoma: a single center survey.
Topics: Adolescent; Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazin | 2016 |
Spermatogenesis in Hodgkin's lymphoma patients: a retrospective study of semen quality before and after different chemotherapy regimens.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dacarbazine; Doxorubici | 2016 |
Gonadal damage in Hodgkin's disease from cancer chemotherapeutic regimens.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Castration; Dacarbazin | 1984 |
A rat model for chemotherapy-induced male infertility.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Disease Models, Animal; Drug Therapy, Combination; | 1983 |
Clomiphene citrate reduces procarbazine-induced sterility in a rat model.
Topics: Animals; Clomiphene; Infertility, Male; Male; Procarbazine; Rats; Rats, Wistar; Spermatogenesis; Tes | 1995 |
Testicular function following the treatment of Hodgkin's disease in childhood.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy; | 1993 |
Protection from procarbazine-induced testicular damage by hormonal pretreatment does not involve arrest of spermatogonial proliferation.
Topics: Animals; Cell Division; DNA Replication; Drug Administration Schedule; Drug Implants; Estradiol; Gro | 1997 |
Hormonal treatment after cytotoxic therapy stimulates recovery of spermatogenesis.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Cell Differentiation; Female; Folli | 1999 |
Follow-up of sperm concentration and motility in patients with lymphoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cryopreservation; Daca | 2000 |
Cyclical combination chemotherapy and gonadal function. Retrospective study in males.
Topics: Adolescent; Adult; Aged; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; | 1979 |
[Chemotherapies and fecondity (author's transl)].
Topics: Alkaloids; Antineoplastic Agents; Dactinomycin; Female; Humans; Infertility, Female; Infertility, Ma | 1979 |
Testicular dysfunction after cyclophosphamide-vincristine-procarbazine-prednisolone chemotherapy for advanced Hodgkin's disease. A long-term follow-up study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Follicle Stimul | 1990 |
Protection by steroid contraceptives against procarbazine-induced sterility and genotoxicity in male rats.
Topics: Animals; Drug Therapy, Combination; Epididymis; Infertility, Male; Male; Medroxyprogesterone; Medrox | 1990 |