Page last updated: 2024-11-03

procarbazine and Spinal Muscular Atrophies of Childhood

procarbazine has been researched along with Spinal Muscular Atrophies of Childhood in 1 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Spinal Muscular Atrophies of Childhood: A group of recessive inherited diseases that feature progressive muscular atrophy and hypotonia. They are classified as type I (Werdnig-Hoffman disease), type II (intermediate form), and type III (Kugelberg-Welander disease). Type I is fatal in infancy, type II has a late infantile onset and is associated with survival into the second or third decade. Type III has its onset in childhood, and is slowly progressive. (J Med Genet 1996 Apr:33(4):281-3)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Thomson, JA1
Seymour, JF1
Wolf, M1

Other Studies

1 other study available for procarbazine and Spinal Muscular Atrophies of Childhood

ArticleYear
Hodgkin's disease complicated by the nephrotic syndrome in a man with Kugelberg-Welander disease.
    Leukemia & lymphoma, 2001, Volume: 42, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bleomycin; Cyclophosphamide; Doxorubi

2001