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procarbazine and Sarcoma

procarbazine has been researched along with Sarcoma in 5 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Sarcoma: A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.

Research Excerpts

ExcerptRelevanceReference
"Although it is accepted that pediatric cancer treatment harbors a risk of gonadal damage, large cohort studies using up-to-date fertility markers are lacking."1.35Effect of childhood cancer treatment on fertility markers in adult male long-term survivors. ( Dohle, GR; Hählen, K; Hakvoort-Cammel, FG; van Casteren, NJ; van den Heuvel-Eibrink, MM; van der Linden, GH, 2009)
"Bone and soft tissue sarcomas have rarely been observed after treatment of Hodgkin's disease, and only a few cases are described in the literature."1.27Bone and soft tissue sarcomas in the follow-up of Hodgkin's disease. ( Banfi, A; Zanini, M; Zucali, R, 1983)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
van Casteren, NJ1
van der Linden, GH1
Hakvoort-Cammel, FG1
Hählen, K1
Dohle, GR1
van den Heuvel-Eibrink, MM1
Zanini, M1
Zucali, R1
Banfi, A1
Bacci, M1
Cavaliere, A1
Amorosi, A1
Carl, W1
Morrone, G1

Reviews

1 review available for procarbazine and Sarcoma

ArticleYear
[Cytostatic chemotherapy of neoplasms in children].
    La Pediatria, 1971, Volume: 79, Issue:1

    Topics: Adrenal Cortex Hormones; Aminopterin; Antineoplastic Agents; Asparaginase; Child; Child, Preschool;

1971

Other Studies

4 other studies available for procarbazine and Sarcoma

ArticleYear
Effect of childhood cancer treatment on fertility markers in adult male long-term survivors.
    Pediatric blood & cancer, 2009, Volume: 52, Issue:1

    Topics: Biomarkers; Child, Preschool; Cyclophosphamide; Female; Fertility; Follicle Stimulating Hormone; Fol

2009
Bone and soft tissue sarcomas in the follow-up of Hodgkin's disease.
    Tumori, 1983, Oct-31, Volume: 69, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child,

1983
Procarbazine hydrochlorate carcinogenesis in Osborne-Mendel rats.
    Oncology, 1984, Volume: 41, Issue:2

    Topics: Animals; Carcinogens; Carcinoma; Female; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Medi

1984
Cancer chemotherapy and dentistry.
    Quintessence international, dental digest, 1977, Volume: 8, Issue:12

    Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Asparaginase; Carci

1977