procarbazine has been researched along with Sarcoma, Ewing in 4 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Sarcoma, Ewing: A malignant tumor of the bone which always arises in the medullary tissue, occurring more often in cylindrical bones. The tumor occurs usually before the age of 20, about twice as frequently in males as in females.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the value in Ewing's sarcoma of a new multiagent therapy (vincristine, cyclophosphamide, Adriamycin, (doxorubicin) procarbazine), 30 children with a localized tumor (eight distal, nine proximal, 13 central lesions) treated at the Institut Gustave-Roussy between 1973 and 1976 (E3), were pair-matched by site of primary with 30 control patients treated without intensive chemotherapy between 1967 and 1972 (E1) at the same institution, both groups having the same local radiotherapy." | 2.65 | Intensive systemic chemotherapy in localized Ewing's sarcoma in childhood. A historical trial. ( Blache, R; Henry-Amar, M; Patte, C; Sarrazin, D; Schweisguth, O; Zucker, JM, 1983) |
| "Two osteosarcomas, an Ewing sarcoma, and a bronchogenic carcinoma were also studied and grew similarly." | 1.26 | Growth of human tumors in mice after short-term immunosuppression with procarbazine, cyclophosphamide, and antilymphocyte serum. ( Floersheim, GL; Nassenstein, D; Torhorst, J, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zucker, JM | 1 |
| Henry-Amar, M | 1 |
| Sarrazin, D | 1 |
| Blache, R | 1 |
| Patte, C | 1 |
| Schweisguth, O | 1 |
| Floersheim, GL | 1 |
| Nassenstein, D | 1 |
| Torhorst, J | 1 |
| Le Mevel, BP | 2 |
| Hoerni, B | 1 |
| Durant, D | 1 |
| Kenesi, C | 1 |
| Salle, M | 1 |
| Trifaud, A | 1 |
| Liegey-Bagari, D | 1 |
| Bainvel, JV | 1 |
| Rogez, JM | 1 |
| Fumoleau, P | 1 |
| Mazabraud, A | 1 |
| Dumont, J | 1 |
| Tomend, B | 1 |
| Brossel, E | 1 |
| Garetta, M | 1 |
| Guerrin, D | 1 |
| Jasmin, C | 1 |
| Sancho-Garnier, H | 1 |
| Gimenez, M | 1 |
2 trials available for procarbazine and Sarcoma, Ewing
| Article | Year |
|---|---|
Intensive systemic chemotherapy in localized Ewing's sarcoma in childhood. A historical trial.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Neopl | 1983 |
Ewing's sarcoma: 5-year survival under adjuvant chemotherapy.
Topics: Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Administration Schedule; | 1982 |
2 other studies available for procarbazine and Sarcoma, Ewing
| Article | Year |
|---|---|
Growth of human tumors in mice after short-term immunosuppression with procarbazine, cyclophosphamide, and antilymphocyte serum.
Topics: Adenocarcinoma; Adolescent; Adult; Animals; Antilymphocyte Serum; Bone Neoplasms; Carcinoma; Child; | 1980 |
EORTC/GTO adjuvant chemotherapy program for primary Ewing's sarcoma: results at 5 years.
Topics: Antineoplastic Agents; Bone Neoplasms; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Administrat | 1978 |