procarbazine has been researched along with Pyrexia in 9 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Excerpt | Relevance | Reference |
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"A case of hyperpyrexia induced by procarbazine in a child with Hodgkin's disease, neurofibromatosis, and pectus excavatum deformity is presented." | 7.68 | Cytotoxic drug-induced fever: a report on procarbazine-induced hyperpyrexia. ( Akyol, H; Akyüz, C; Büyükpamukçu, M; Sarialioğlu, F, 1990) |
"A case of hyperpyrexia induced by procarbazine in a child with Hodgkin's disease, neurofibromatosis, and pectus excavatum deformity is presented." | 3.68 | Cytotoxic drug-induced fever: a report on procarbazine-induced hyperpyrexia. ( Akyol, H; Akyüz, C; Büyükpamukçu, M; Sarialioğlu, F, 1990) |
"The clinical efficacy of COP-BLAM chemotherapy combined with human recombinant granulocyte colony-stimulating factor (G-CSF) was evaluated in 104 previously untreated patients with non-Hodgkin's lymphoma (NHL)." | 2.68 | COP-BLAM regimen combined with granulocyte colony-stimulating factor and high-grade non-Hodgkin's lymphoma. ( Niitsu, N; Umeda, M, 1995) |
"Cholestasis was observed in all cases; in most patients a moderate increase in the transaminase activity was also seen." | 1.29 | Hodgkin's disease presenting as a cholestatic febrile illness: incidence and main characteristics in a series of 421 patients. ( Briones, J; Bruguera, M; Cervantes, F; Font, C; Grau, JM; Montserrat, E; Rozman, C, 1996) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (33.33) | 18.7374 |
1990's | 4 (44.44) | 18.2507 |
2000's | 1 (11.11) | 29.6817 |
2010's | 1 (11.11) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Kurz, M | 1 |
Stoeckle, M | 1 |
Krasniqi, F | 1 |
Battegay, M | 1 |
Marzolini, C | 1 |
Engelhard, M | 1 |
Gerhartz, H | 1 |
Brittinger, G | 1 |
Engert, A | 1 |
Fuchs, R | 1 |
Geiseler, B | 1 |
Gerhartz, D | 1 |
Haunauske, AR | 1 |
Hartlapp, HJ | 1 |
Huhn, D | 1 |
Niitsu, N | 1 |
Umeda, M | 1 |
Cervantes, F | 1 |
Briones, J | 1 |
Bruguera, M | 1 |
Font, C | 1 |
Grau, JM | 1 |
Rozman, C | 1 |
Montserrat, E | 1 |
Chim, CS | 1 |
Choy, C | 1 |
Ooi, CG | 1 |
Liang, R | 1 |
Akyol, H | 1 |
Sarialioğlu, F | 1 |
Büyükpamukçu, M | 1 |
Akyüz, C | 1 |
Heinrich, M | 1 |
Osswald, H | 1 |
Anderson, T | 1 |
Schein, PS | 1 |
Jencks, JA | 1 |
Binder, RA | 1 |
Jones, SE | 1 |
Moore, M | 1 |
Blank, N | 1 |
Castellino, RA | 1 |
2 trials available for procarbazine and Pyrexia
Article | Year |
---|---|
Cytokine efficiency in the treatment of high-grade malignant non-Hodgkin's lymphomas: results of a randomized double-blind placebo-controlled study with intensified COP-BLAM +/- rhGM-CSF.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit | 1994 |
COP-BLAM regimen combined with granulocyte colony-stimulating factor and high-grade non-Hodgkin's lymphoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomyci | 1995 |
7 other studies available for procarbazine and Pyrexia
Article | Year |
---|---|
Etravirine: a good option for concomitant use with chemotherapy for Hodgkin's lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bleomycin; Cyclophosphamide; Doxorubicin; Et | 2015 |
Hodgkin's disease presenting as a cholestatic febrile illness: incidence and main characteristics in a series of 421 patients.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cholestas | 1996 |
Hodgkin's disease with primary manifestation in the liver.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cyclophosphamide; Diagnosis, Different | 2000 |
Cytotoxic drug-induced fever: a report on procarbazine-induced hyperpyrexia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophosphamide; Diagnosis, Differential; Fe | 1990 |
[Test of multi-step-therapy of cancer (combination of pretreatment with glucose with chemotherapy and whole body hyperthermia) in Walker- and DS-carcinosarcoma of rat (author's transl)].
Topics: Animals; Carcinoma 256, Walker; Carcinosarcoma; Cyclophosphamide; Female; Fever; Germ-Free Life; Glu | 1974 |
The nitroblue tetrazolium (NBT) dye test in determining fever source in lymphoma.
Topics: Bacterial Infections; Diagnosis, Differential; Evaluation Studies as Topic; False Positive Reactions | 1974 |
Hypersensitivity to procarbazine (Matulane) manifested by fever and pleuropulmonary reaction.
Topics: Administration, Oral; Antineoplastic Agents; Benzoates; Diagnosis, Differential; Drug Combinations; | 1972 |