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procarbazine and Pyrexia

procarbazine has been researched along with Pyrexia in 9 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Research Excerpts

ExcerptRelevanceReference
"A case of hyperpyrexia induced by procarbazine in a child with Hodgkin's disease, neurofibromatosis, and pectus excavatum deformity is presented."7.68Cytotoxic drug-induced fever: a report on procarbazine-induced hyperpyrexia. ( Akyol, H; Akyüz, C; Büyükpamukçu, M; Sarialioğlu, F, 1990)
"A case of hyperpyrexia induced by procarbazine in a child with Hodgkin's disease, neurofibromatosis, and pectus excavatum deformity is presented."3.68Cytotoxic drug-induced fever: a report on procarbazine-induced hyperpyrexia. ( Akyol, H; Akyüz, C; Büyükpamukçu, M; Sarialioğlu, F, 1990)
"The clinical efficacy of COP-BLAM chemotherapy combined with human recombinant granulocyte colony-stimulating factor (G-CSF) was evaluated in 104 previously untreated patients with non-Hodgkin's lymphoma (NHL)."2.68COP-BLAM regimen combined with granulocyte colony-stimulating factor and high-grade non-Hodgkin's lymphoma. ( Niitsu, N; Umeda, M, 1995)
"Cholestasis was observed in all cases; in most patients a moderate increase in the transaminase activity was also seen."1.29Hodgkin's disease presenting as a cholestatic febrile illness: incidence and main characteristics in a series of 421 patients. ( Briones, J; Bruguera, M; Cervantes, F; Font, C; Grau, JM; Montserrat, E; Rozman, C, 1996)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's4 (44.44)18.2507
2000's1 (11.11)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kurz, M1
Stoeckle, M1
Krasniqi, F1
Battegay, M1
Marzolini, C1
Engelhard, M1
Gerhartz, H1
Brittinger, G1
Engert, A1
Fuchs, R1
Geiseler, B1
Gerhartz, D1
Haunauske, AR1
Hartlapp, HJ1
Huhn, D1
Niitsu, N1
Umeda, M1
Cervantes, F1
Briones, J1
Bruguera, M1
Font, C1
Grau, JM1
Rozman, C1
Montserrat, E1
Chim, CS1
Choy, C1
Ooi, CG1
Liang, R1
Akyol, H1
Sarialioğlu, F1
Büyükpamukçu, M1
Akyüz, C1
Heinrich, M1
Osswald, H1
Anderson, T1
Schein, PS1
Jencks, JA1
Binder, RA1
Jones, SE1
Moore, M1
Blank, N1
Castellino, RA1

Trials

2 trials available for procarbazine and Pyrexia

ArticleYear
Cytokine efficiency in the treatment of high-grade malignant non-Hodgkin's lymphomas: results of a randomized double-blind placebo-controlled study with intensified COP-BLAM +/- rhGM-CSF.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5 Suppl 2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit

1994
COP-BLAM regimen combined with granulocyte colony-stimulating factor and high-grade non-Hodgkin's lymphoma.
    European journal of haematology, 1995, Volume: 55, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomyci

1995

Other Studies

7 other studies available for procarbazine and Pyrexia

ArticleYear
Etravirine: a good option for concomitant use with chemotherapy for Hodgkin's lymphoma.
    International journal of STD & AIDS, 2015, Volume: 26, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bleomycin; Cyclophosphamide; Doxorubicin; Et

2015
Hodgkin's disease presenting as a cholestatic febrile illness: incidence and main characteristics in a series of 421 patients.
    Annals of hematology, 1996, Volume: 72, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cholestas

1996
Hodgkin's disease with primary manifestation in the liver.
    Leukemia & lymphoma, 2000, Volume: 37, Issue:5-6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cyclophosphamide; Diagnosis, Different

2000
Cytotoxic drug-induced fever: a report on procarbazine-induced hyperpyrexia.
    Medical and pediatric oncology, 1990, Volume: 18, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophosphamide; Diagnosis, Differential; Fe

1990
[Test of multi-step-therapy of cancer (combination of pretreatment with glucose with chemotherapy and whole body hyperthermia) in Walker- and DS-carcinosarcoma of rat (author's transl)].
    Archiv fur Geschwulstforschung, 1974, Volume: 43, Issue:4

    Topics: Animals; Carcinoma 256, Walker; Carcinosarcoma; Cyclophosphamide; Female; Fever; Germ-Free Life; Glu

1974
The nitroblue tetrazolium (NBT) dye test in determining fever source in lymphoma.
    Cancer, 1974, Volume: 34, Issue:3

    Topics: Bacterial Infections; Diagnosis, Differential; Evaluation Studies as Topic; False Positive Reactions

1974
Hypersensitivity to procarbazine (Matulane) manifested by fever and pleuropulmonary reaction.
    Cancer, 1972, Volume: 29, Issue:2

    Topics: Administration, Oral; Antineoplastic Agents; Benzoates; Diagnosis, Differential; Drug Combinations;

1972