procarbazine has been researched along with Purpura, Thrombocytopenic, Idiopathic in 3 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Purpura, Thrombocytopenic, Idiopathic: Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic idiopathic thrombocytopenic purpura is a destructive thrombocytopenia caused by an autoantibody." | 1.29 | Combination chemotherapy in refractory immune thrombocytopenic purpura. ( Figueroa, M; Gehlsen, J; Hammond, D; McMillan, R; Ondreyco, S; Piro, L; Pomeroy, T; Williams, F, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rancea, M | 1 |
| Skoetz, N | 1 |
| Monsef, I | 1 |
| Hübel, K | 1 |
| Engert, A | 1 |
| Bauer, K | 1 |
| Figueroa, M | 1 |
| Gehlsen, J | 1 |
| Hammond, D | 1 |
| Ondreyco, S | 1 |
| Piro, L | 1 |
| Pomeroy, T | 1 |
| Williams, F | 1 |
| McMillan, R | 1 |
| Maslovsky, I | 1 |
| Volchek, L | 1 |
| Blumental, R | 1 |
| Ducach, A | 1 |
| Lugassy, G | 1 |
1 review available for procarbazine and Purpura, Thrombocytopenic, Idiopathic
| Article | Year |
|---|---|
Fourteenth biannual report of the Cochrane Haematological Malignancies Group--focus on autologous stem cell transplantation in hematological malignancies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Colony-Stimulating Factors; Cyclophospham | 2012 |
2 other studies available for procarbazine and Purpura, Thrombocytopenic, Idiopathic
| Article | Year |
|---|---|
Combination chemotherapy in refractory immune thrombocytopenic purpura.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Etoposide; Female; Hu | 1993 |
Persistent paraneoplastic neurologic syndrome after successful therapy of Hodgkin's disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Ataxia; Bleomycin; Combined Modality Therapy; | 2001 |