procarbazine has been researched along with Pulmonary Fibrosis in 8 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weiss, RB | 1 |
| Muggia, FM | 1 |
| Niitsu, N | 1 |
| Umeda, M | 1 |
| Kozielski, J | 1 |
| Rauer, R | 1 |
| Ziora, D | 1 |
| Spychałowicz, W | 1 |
| Jensen, BV | 1 |
| Carlsen, NL | 1 |
| Nissen, NI | 1 |
| Luisetti, M | 1 |
| Peona, V | 1 |
| Salmona, M | 1 |
| Pagnoni, AM | 1 |
| Villani, F | 1 |
| Knerich, R | 1 |
| Genghini, M | 1 |
| Abbà, L | 1 |
| Pozzi, E | 1 |
| Brooks, BJ | 1 |
| Seifter, EJ | 1 |
| Walsh, TE | 1 |
| Lichter, AS | 1 |
| Bunn, PA | 1 |
| Zabell, A | 1 |
| Johnston-Early, A | 1 |
| Edison, M | 1 |
| Makuch, RW | 1 |
| Cohen, MH | 1 |
| Garbes, ID | 1 |
| Henderson, ES | 1 |
| Gomez, GA | 1 |
| Bakshi, SP | 1 |
| Parthasarathy, KL | 1 |
| Castillo, NB | 1 |
| Grundmann, E | 1 |
| Fritzsche, R | 1 |
1 review available for procarbazine and Pulmonary Fibrosis
| Article | Year |
|---|---|
Cytotoxic drug-induced pulmonary disease: update 1980.
Topics: Alkylating Agents; Antineoplastic Agents; Bleomycin; Drug Administration Schedule; Drug Synergism; D | 1980 |
1 trial available for procarbazine and Pulmonary Fibrosis
| Article | Year |
|---|---|
Pulmonary toxicity with combined modality therapy for limited stage small-cell lung cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modalit | 1986 |
6 other studies available for procarbazine and Pulmonary Fibrosis
| Article | Year |
|---|---|
[Type III procollagen N-terminal peptide and type IV collagen-7S level in the serum and BALF of patients with non-Hodgkin's lymphoma before and after chemotherapy].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bronchoalveolar | 1994 |
[Lung fibrosis after bleomycin therapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Hodgkin Disease; Humans | 1994 |
Influence of age and duration of follow-up on lung function after combined chemotherapy for Hodgkin's disease.
Topics: Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Femal | 1990 |
Ambroxol and pulmonary toxicity induced by antineoplastic drugs.
Topics: Ambroxol; Animals; Antineoplastic Agents; Bleomycin; Bromhexine; Busulfan; Cyclophosphamide; Humans; | 1986 |
Procarbazine-induced interstitial pneumonitis with a normal chest x-ray: a case report.
Topics: Gallium Radioisotopes; Hodgkin Disease; Humans; Lung; Male; Middle Aged; Procarbazine; Pulmonary Fib | 1986 |
[Pathology of treated Hodgkin's disease. A retrospective study (author's transl)].
Topics: Adolescent; Adult; Age Factors; Aged; Autopsy; Child; Child, Preschool; Drug Therapy, Combination; D | 1974 |