procarbazine has been researched along with Precursor Cell Lymphoblastic Leukemia-Lymphoma in 8 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Precursor Cell Lymphoblastic Leukemia-Lymphoma: A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We reviewed all reported cases of Burkitt's lymphoma and/or Burkitt's leukemia (BLL) occurring following therapy for Hodgkin's disease." | 2.39 | Burkitt's lymphoma-leukemia in patients treated for Hodgkin's disease. ( Cooper, DL; Levy, A; Salloum, E; Tallini, G, 1996) |
| "Concerning ANLL, the MOPP regimen was significantly associated with a higher risk: 3." | 1.31 | Fifteen-year secondary leukaemia risk observed in 761 patients with Hodgkin's disease prospectively treated by MOPP or ABVD chemotherapy plus high-dose irradiation. ( Andrieu, JM; Colonna, P; Delwail, V; Jais, JP, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kober, T | 1 |
| Hülsewede, H | 1 |
| Bohlius, J | 1 |
| Engert, A | 1 |
| Chamberlain, MC | 1 |
| Nishikawa, K | 1 |
| Salloum, E | 1 |
| Tallini, G | 1 |
| Levy, A | 1 |
| Cooper, DL | 1 |
| Soriano Guillén , L | 1 |
| Muñoz Calvo , MT | 1 |
| Pozo Román , J | 1 |
| Contra Gómez , T | 1 |
| Buño Soto , M | 1 |
| Argente Oliver , J | 1 |
| Chen, YC | 1 |
| Ho, CL | 1 |
| Kao, WY | 1 |
| Hwang, JM | 1 |
| Sheu, LF | 1 |
| Chao, TY | 1 |
| Delwail, V | 1 |
| Jais, JP | 1 |
| Colonna, P | 1 |
| Andrieu, JM | 1 |
| Swaffar, DS | 1 |
| Pomerantz, SC | 1 |
| Harker, WG | 1 |
| Yost, GS | 1 |
3 reviews available for procarbazine and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
Fourth biannual report of the Cochrane Haematological Malignancies Group.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy | 2006 |
[Chemotherapy of relapsed AML and ALL].
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Etoposide; Granulocyte Col | 1996 |
Burkitt's lymphoma-leukemia in patients treated for Hodgkin's disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Burkitt Lymphoma; Cyclophosphamide | 1996 |
5 other studies available for procarbazine and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
Long survival in patients with acquired immune deficiency syndrome-related primary central nervous system lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; C | 1994 |
[Changes in gonadal function in post-pubertal male survivors of acute lymphoblastic leukemia and Hodgkin's disease].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Child; Cycl | 2000 |
Adult lymphoblastic lymphoma in Taiwan: an analysis of treatment results of 26 patients.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow T | 2001 |
Fifteen-year secondary leukaemia risk observed in 761 patients with Hodgkin's disease prospectively treated by MOPP or ABVD chemotherapy plus high-dose irradiation.
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbaz | 2002 |
Non-enzymatic activation of procarbazine to active cytotoxic species.
Topics: Biotransformation; Cell Division; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Cy | 1992 |