Page last updated: 2024-11-03

procarbazine and Pancytopenia

procarbazine has been researched along with Pancytopenia in 3 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Pancytopenia: Deficiency of all three cell elements of the blood, erythrocytes, leukocytes and platelets.

Research Excerpts

ExcerptRelevanceReference
"Between 1978 and 1988, 20 children with medulloblastoma (MB) of the brain were treated postoperatively with MOPP (nitrogen mustard, vincristine, prednisone, and procarbazine)."3.68Therapy-related myelodysplastic syndrome in children with medulloblastoma following MOPP chemotherapy. ( Hayani, A; Mahoney, DH; Taylor, LD, 1992)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brusamolino, E1
Orlandi, E1
Canevari, A1
Morra, E1
Castelli, G1
Alessandrino, EP1
Pagnucco, G1
Bernasconi, P1
Astori, C1
Lazzarino, M1
Hayani, A1
Mahoney, DH1
Taylor, LD1
Carroll, WL1
Berberich, FR1
Glader, BE1

Other Studies

3 other studies available for procarbazine and Pancytopenia

ArticleYear
Results of CAV regimen (CCNU, melphalan, and VP-16) as third-line salvage therapy for Hodgkin's disease.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Dox

1994
Therapy-related myelodysplastic syndrome in children with medulloblastoma following MOPP chemotherapy.
    Journal of neuro-oncology, 1992, Volume: 14, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Preschool

1992
Pancytopenia with myelofibrosis. An unusual presentation of childhood Hodgkin's disease.
    Clinical pediatrics, 1986, Volume: 25, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Female; Hodgkin Disease; Humans;

1986