Page last updated: 2024-11-03

procarbazine and POEMS Syndrome

procarbazine has been researched along with POEMS Syndrome in 1 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

POEMS Syndrome: A multisystemic disorder characterized by a sensorimotor polyneuropathy (POLYNEUROPATHIES), organomegaly, endocrinopathy, monoclonal gammopathy, and pigmentary skin changes. Other clinical features which may be present include EDEMA; CACHEXIA; microangiopathic glomerulopathy; pulmonary hypertension (HYPERTENSION, PULMONARY); cutaneous necrosis; THROMBOCYTOSIS; and POLYCYTHEMIA. This disorder is frequently associated with osteosclerotic myeloma. (From Adams et al., Principles of Neurology, 6th ed, p1335; Rev Med Interne 1997;18(7):553-62)

Research Excerpts

ExcerptRelevanceReference
"Waldenström's macroglobulinemia (WM) is a neoplasm of lymphoplasmacytic cells that produces monoclonal IgM protein."1.42Successful Treatment of Bing-Neel Syndrome Accompanying Waldenström's Macroglobulinemia with R-MPV: A Case Report. ( Endo, S; Hata, H; Kawano, Y; Kikukawa, Y; Mitsuya, H; Miyagawa, E; Okuno, Y; Ueno, S; Yamamura-Fujimoto, A, 2015)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kikukawa, Y1
Yamamura-Fujimoto, A1
Endo, S1
Miyagawa, E1
Kawano, Y1
Ueno, S1
Mitsuya, H1
Hata, H1
Okuno, Y1

Other Studies

1 other study available for procarbazine and POEMS Syndrome

ArticleYear
Successful Treatment of Bing-Neel Syndrome Accompanying Waldenström's Macroglobulinemia with R-MPV: A Case Report.
    Journal of clinical and experimental hematopathology : JCEH, 2015, Volume: 55, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Female; Humans; Lymphoma, Large B-C

2015