procarbazine has been researched along with Ovarian Neoplasms in 7 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " After a median follow-up of more than 6 years following MOPP (mechlorethamine/vincristine/procarbazine/prednisone) chemotherapy with or without radiotherapy, 5% of patients with Hodgkin's disease developed second primaries, 60% of which were leukemias." | 4.78 | Cytotoxic chemotherapy-induced second primary neoplasms: clinical aspects. ( Petru, E; Schmähl, D, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fazio, M | 1 |
| Airoldi, M | 1 |
| Bellardo, A | 1 |
| Cavallero, P | 1 |
| Mastromatteo, V | 1 |
| Minnella, R | 1 |
| Pecchio, F | 1 |
| Mattern, J | 1 |
| Kaufmann, M | 1 |
| Hinderer, H | 1 |
| Wayss, K | 1 |
| Volm, M | 1 |
| Vinokurov, VL | 1 |
| Vinokurova, NA | 1 |
| Young, RC | 1 |
| Baumgartner, G | 1 |
| Petru, E | 1 |
| Schmähl, D | 1 |
| Goldenson, Y | 1 |
| Lev, L | 1 |
| Robinson, E | 1 |
3 reviews available for procarbazine and Ovarian Neoplasms
| Article | Year |
|---|---|
Chemotherapy of ovarian cancer: past and present.
Topics: Acrylates; Alkylating Agents; Altretamine; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Do | 1975 |
Cytotoxic chemotherapy-induced second primary neoplasms: clinical aspects.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Hod | 1991 |
[Combination chemotherapy in the treatment of cancer].
Topics: Administration, Oral; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Dacti | 1972 |
1 trial available for procarbazine and Ovarian Neoplasms
| Article | Year |
|---|---|
[Therapeutic effect of natulan in a recurrence of a granulosa theca cell tumor of the ovaries (1 case)].
Topics: Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Middle Aged; N | 1979 |
3 other studies available for procarbazine and Ovarian Neoplasms
| Article | Year |
|---|---|
[Evaluation of serum BuChe activity during polychemotherapy based on COP and C-MOPP protocols].
Topics: Cholinesterases; Cyclophosphamide; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Ovari | 1981 |
Sensitivity tests of tumors to cytostatic agents. II. Investigation on human tumors.
Topics: Antineoplastic Agents; Autoradiography; Breast Neoplasms; Cell Count; Cell Division; Culture Techniq | 1975 |
[Cytostatic therapy of inoperable carcinomas].
Topics: Breast Neoplasms; Bronchial Neoplasms; Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin | 1976 |