procarbazine has been researched along with Osteogenic Sarcoma in 5 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This article reports a patient with Hodgkin's disease in remission after combined modality therapy who developed metastatic pulmonary osteosarcoma, subsequently found to originate in soft tissue of the mediastinum, within a field irradiated 11 years previously." | 2.37 | Mediastinal osteosarcoma with extension to lungs in a patient treated for Hodgkin's disease. ( Andres, DF; Catanese, J; Dorfman, HD; Dutcher, JP; Wiernik, PH, 1988) |
| "Two osteosarcomas, an Ewing sarcoma, and a bronchogenic carcinoma were also studied and grew similarly." | 1.26 | Growth of human tumors in mice after short-term immunosuppression with procarbazine, cyclophosphamide, and antilymphocyte serum. ( Floersheim, GL; Nassenstein, D; Torhorst, J, 1980) |
| "Patients treated for Hodgkin's disease are exposed to increased risk for second malignancies, a fact which has been well documented in the past decade." | 1.26 | [Therapy-induced osteosarcoma in Hodgkin's disease]. ( Bamberg, M; Donhuijsen, K, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moser, K | 1 |
| Pohl, A | 1 |
| Floersheim, GL | 1 |
| Nassenstein, D | 1 |
| Torhorst, J | 1 |
| Donhuijsen, K | 1 |
| Bamberg, M | 1 |
| Sutow, WW | 1 |
| Sullivan, MP | 1 |
| Catanese, J | 1 |
| Dutcher, JP | 1 |
| Dorfman, HD | 1 |
| Andres, DF | 1 |
| Wiernik, PH | 1 |
2 reviews available for procarbazine and Osteogenic Sarcoma
| Article | Year |
|---|---|
[Recent developments in chemotherapy of malignant diseases].
Topics: Anthraquinones; Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy | 1982 |
Mediastinal osteosarcoma with extension to lungs in a patient treated for Hodgkin's disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Hodgkin Disease; H | 1988 |
3 other studies available for procarbazine and Osteogenic Sarcoma
| Article | Year |
|---|---|
Growth of human tumors in mice after short-term immunosuppression with procarbazine, cyclophosphamide, and antilymphocyte serum.
Topics: Adenocarcinoma; Adolescent; Adult; Animals; Antilymphocyte Serum; Bone Neoplasms; Carcinoma; Child; | 1980 |
[Therapy-induced osteosarcoma in Hodgkin's disease].
Topics: Adolescent; Cyclophosphamide; Doxorubicin; Hodgkin Disease; Humans; Male; Mustard Compounds; Neoplas | 1981 |
Childhood cancer: the improving prognosis.
Topics: Asparaginase; Child; Cyclophosphamide; Cytosine; Daunorubicin; Doxorubicin; Drug Therapy, Combinatio | 1976 |