procarbazine has been researched along with Optic Nerve Diseases in 2 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Optic Nerve Diseases: Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This case of optic neuropathy is supposed to be a rare example of involvement of the 2nd cranial nerve due to vinca alkaloids." | 1.27 | Transient optic neuropathy secondary to MOPP chemotherapy in Hodgkin's disease: report of a case. ( Guidelli Guidi, S; Maccolini, E; Oddo Bravetti, G; Serra, L; Vecchi, V, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vecchi, V | 1 |
| Maccolini, E | 1 |
| Oddo Bravetti, G | 1 |
| Guidelli Guidi, S | 1 |
| Serra, L | 1 |
| Albers, GW | 1 |
| Hoyt, WF | 1 |
| Forno, LS | 1 |
| Shratter, LA | 1 |
2 other studies available for procarbazine and Optic Nerve Diseases
| Article | Year |
|---|---|
Transient optic neuropathy secondary to MOPP chemotherapy in Hodgkin's disease: report of a case.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Female; Hodgkin Disease; Humans; Mechloretham | 1984 |
Treatment response in malignant optic glioma of adulthood.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Cranial Nerve Neoplasms; F | 1988 |