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procarbazine and Opportunistic Infections

procarbazine has been researched along with Opportunistic Infections in 6 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Opportunistic Infections: An infection caused by an organism which becomes pathogenic under certain conditions, e.g., during immunosuppression.

Research Excerpts

ExcerptRelevanceReference
"Procarbazine was recognized as major gonadotoxic agent in boys and eliminated successively from the treatment regimens."2.53Late Effects Following Treatment of Hodgkin Lymphoma During Childhood and Adolescence. Results of the Hodgkin Lymphoma Late Effects Research Project. ( Brämswig, J; Dörffel, W; Lüders, H; Riepenhausen, M, 2016)
"A case of Hodgkin's disease associated from the start with visceral leishmaniasis in the absence of antitumoral treatment shows that leishmaniasis is a severe opportunistic infection in endemic areas and can be masked by the tumoral syndrome of an underlying pathology."2.38[Visceral leishmaniasis associated with Hodgkin's disease: diagnostic difficulties]. ( Blanc, AP; Jacquème, P; Magnan, A; Poirier, R; Redding, E; Sudan, N, 1991)
" Despite prompt initiation of antimycotic therapy the outcome was fatal; dosage of conventional and liposomal amphotericin B was limited due to treatment-related toxicities."1.31A novel type of metastatically spreading subcutaneous aspergillosis without epidermal lesions following allogeneic stem cell transplantation. ( Bethe, U; Cornely, OA; Pels, H; Ritzkowsky, A; Seibold, M; Soehngen, D; Toepelt, K, 2001)
"Sixty-three cases of Hodgkin's disease in intravenous drug users (IVDUs) have been collected by the Italian Cooperative Group on AIDS-Related Tumors (GICAT)."1.28Hodgkin's disease in 63 intravenous drug users infected with human immunodeficiency virus. Gruppo Italiano Cooperativo AIDS & Tumori (GICAT). ( Foà, R; Gavosto, F; Monfardini, S; Tirelli, U; Vaccher, E, 1991)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's2 (33.33)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dörffel, W1
Riepenhausen, M1
Lüders, H1
Brämswig, J1
Tirelli, U2
Vaccher, E2
Spina, M1
Carbone, A1
Cornely, OA1
Pels, H1
Bethe, U1
Seibold, M1
Toepelt, K1
Soehngen, D1
Ritzkowsky, A1
Monfardini, S1
Foà, R1
Gavosto, F1
Magnan, A1
Jacquème, P1
Sudan, N1
Redding, E1
Blanc, AP1
Poirier, R1
Hancock, SL1
Hoppe, RT1
Horning, SJ1
Rosenberg, SA1

Reviews

3 reviews available for procarbazine and Opportunistic Infections

ArticleYear
Late Effects Following Treatment of Hodgkin Lymphoma During Childhood and Adolescence. Results of the Hodgkin Lymphoma Late Effects Research Project.
    Klinische Padiatrie, 2016, Volume: 228, Issue:6-07

    Topics: Adolescent; Child; Combined Modality Therapy; Early Detection of Cancer; Heart; Hodgkin Disease; Hum

2016
Hodgkin's disease: clinical presentation and treatment.
    Cancer treatment and research, 2001, Volume: 104

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Combined

2001
[Visceral leishmaniasis associated with Hodgkin's disease: diagnostic difficulties].
    Revue de pneumologie clinique, 1991, Volume: 47, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antiprotozoal Agents; Bleomycin; Dacarbazine;

1991

Trials

1 trial available for procarbazine and Opportunistic Infections

ArticleYear
Intercurrent death after Hodgkin disease therapy in radiotherapy and adjuvant MOPP trials.
    Annals of internal medicine, 1988, Aug-01, Volume: 109, Issue:3

    Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Cardiovascular Diseases; Clinica

1988

Other Studies

2 other studies available for procarbazine and Opportunistic Infections

ArticleYear
A novel type of metastatically spreading subcutaneous aspergillosis without epidermal lesions following allogeneic stem cell transplantation.
    Bone marrow transplantation, 2001, Volume: 28, Issue:9

    Topics: Adult; Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Aspergillo

2001
Hodgkin's disease in 63 intravenous drug users infected with human immunodeficiency virus. Gruppo Italiano Cooperativo AIDS & Tumori (GICAT).
    Annals of oncology : official journal of the European Society for Medical Oncology, 1991, Volume: 2 Suppl 2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin

1991