procarbazine has been researched along with Nausea in 11 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seventy patients with advanced Hodgkin's disease, 54 with new disease, and 16 in first relapse after initial radiotherapy, have been treated with a seven-drug, 8-month program: MOPP (nitrogen mustard, vincristine, procarbazine, prednisone)/ABV (Adriamycin [Adria Laboratories of Canada, Mississauga, Ontario], bleomycin, vinblastine) hybrid." | 1.27 | MOPP/ABV hybrid program: combination chemotherapy based on early introduction of seven effective drugs for advanced Hodgkin's disease. ( Connors, JM; Klimo, P, 1985) |
| "The eight patients who reported pretreatment nausea had more extensive disease than the other patients and had received twice as much chemotherapy." | 1.26 | Pretreatment nausea in cancer chemotherapy: a conditioned response? ( Carli, T; Curtis, GC; Kleinman, PD; Nesse, RM, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Straus, DJ | 1 |
| Myers, J | 1 |
| Passe, S | 1 |
| Young, CW | 1 |
| Nisce, LZ | 1 |
| Lee, BJ | 1 |
| Koziner, B | 1 |
| Arlin, Z | 1 |
| Kempin, S | 1 |
| Gee, T | 1 |
| Clarkson, BD | 1 |
| Nesse, RM | 1 |
| Carli, T | 1 |
| Curtis, GC | 1 |
| Kleinman, PD | 1 |
| Hartman, HA | 1 |
| Kessinger, A | 1 |
| Lemon, HM | 1 |
| Foley, JF | 1 |
| Viollier, AF | 1 |
| Senn, HJ | 1 |
| Benjamin, RS | 1 |
| Wiernik, PH | 1 |
| O'Connell, MJ | 1 |
| Chang, P | 1 |
| Sutherland, JC | 1 |
| Klener, P | 1 |
| Donner, L | 1 |
| Klimo, P | 1 |
| Connors, JM | 1 |
| Mechl, Z | 1 |
| Krejcí, P | 1 |
| Hartwich, G | 1 |
| Landgren, RC | 1 |
| Hussey, DH | 1 |
| Samuels, ML | 1 |
| Leary, WV | 1 |
| Mubashir, BA | 1 |
| Shullenberger, CC | 1 |
| Gamble, JF | 1 |
2 trials available for procarbazine and Nausea
| Article | Year |
|---|---|
The eight-drug/radiation therapy program (MOPP/ABDV/RT) for advanced Hodgkin's disease: a follow-up report.
Topics: Adolescent; Adult; Antineoplastic Agents; Bleomycin; Dacarbazine; Doxorubicin; Drug Administration S | 1980 |
A randomized study comparing irradiation alone to irradiation plus procarbazine in inoperable bronchogenic carcinoma.
Topics: Antineoplastic Agents; Benzoates; Carcinoma, Bronchogenic; Clinical Trials as Topic; Cobalt Isotopes | 1973 |
9 other studies available for procarbazine and Nausea
| Article | Year |
|---|---|
Pretreatment nausea in cancer chemotherapy: a conditioned response?
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Conditioning, Psycholo | 1980 |
Five-day continuous infusion of 5-fluorouracil for advanced colorectal, gastric, and pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Infus | 1979 |
[Curative aspects of modern combination chemotherapy in generalized malignant lymphomas].
Topics: Agranulocytosis; Cyclophosphamide; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Life | 1976 |
A comparison of cyclophosphamide, vincristine, and prednisone (COP) with nitrogen mustard, vincristine, procarbazine, and prednisone (MOPP) in the treatment of nodular, poorly differentiated, lymphocytic lymphoma.
Topics: Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Female; Humans; Lymphoma, Non-Hodgkin; Male; M | 1976 |
Trichlortriethylamine (TS-160 Spofa) in combination chemotherapy of malignant lymphomas.
Topics: Adult; Aged; Antineoplastic Agents; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Lymp | 1975 |
MOPP/ABV hybrid program: combination chemotherapy based on early introduction of seven effective drugs for advanced Hodgkin's disease.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomyc | 1985 |
Procarbazin in advanced malignant melanoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Female; Humans; Leukopenia; M | 1986 |
[Influencing of side-effects of cytostatic drugs using metoclopramide].
Topics: Amides; Anisoles; Antineoplastic Agents; Benzoates; Carcinoma; Ethylamines; Hodgkin Disease; Humans; | 1973 |
Treatment of advanced Hodgkin's disease with combination chemotherapy.
Topics: Adult; Antineoplastic Agents; Dactinomycin; Drug Therapy, Combination; Female; Hodgkin Disease; Huma | 1973 |