Page last updated: 2024-11-03

procarbazine and Nausea

procarbazine has been researched along with Nausea in 11 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.

Research Excerpts

ExcerptRelevanceReference
"Seventy patients with advanced Hodgkin's disease, 54 with new disease, and 16 in first relapse after initial radiotherapy, have been treated with a seven-drug, 8-month program: MOPP (nitrogen mustard, vincristine, procarbazine, prednisone)/ABV (Adriamycin [Adria Laboratories of Canada, Mississauga, Ontario], bleomycin, vinblastine) hybrid."1.27MOPP/ABV hybrid program: combination chemotherapy based on early introduction of seven effective drugs for advanced Hodgkin's disease. ( Connors, JM; Klimo, P, 1985)
"The eight patients who reported pretreatment nausea had more extensive disease than the other patients and had received twice as much chemotherapy."1.26Pretreatment nausea in cancer chemotherapy: a conditioned response? ( Carli, T; Curtis, GC; Kleinman, PD; Nesse, RM, 1980)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-199011 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Straus, DJ1
Myers, J1
Passe, S1
Young, CW1
Nisce, LZ1
Lee, BJ1
Koziner, B1
Arlin, Z1
Kempin, S1
Gee, T1
Clarkson, BD1
Nesse, RM1
Carli, T1
Curtis, GC1
Kleinman, PD1
Hartman, HA1
Kessinger, A1
Lemon, HM1
Foley, JF1
Viollier, AF1
Senn, HJ1
Benjamin, RS1
Wiernik, PH1
O'Connell, MJ1
Chang, P1
Sutherland, JC1
Klener, P1
Donner, L1
Klimo, P1
Connors, JM1
Mechl, Z1
Krejcí, P1
Hartwich, G1
Landgren, RC1
Hussey, DH1
Samuels, ML1
Leary, WV1
Mubashir, BA1
Shullenberger, CC1
Gamble, JF1

Trials

2 trials available for procarbazine and Nausea

ArticleYear
The eight-drug/radiation therapy program (MOPP/ABDV/RT) for advanced Hodgkin's disease: a follow-up report.
    Cancer, 1980, Jul-15, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents; Bleomycin; Dacarbazine; Doxorubicin; Drug Administration S

1980
A randomized study comparing irradiation alone to irradiation plus procarbazine in inoperable bronchogenic carcinoma.
    Radiology, 1973, Volume: 108, Issue:2

    Topics: Antineoplastic Agents; Benzoates; Carcinoma, Bronchogenic; Clinical Trials as Topic; Cobalt Isotopes

1973

Other Studies

9 other studies available for procarbazine and Nausea

ArticleYear
Pretreatment nausea in cancer chemotherapy: a conditioned response?
    Psychosomatic medicine, 1980, Volume: 42, Issue:1

    Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Conditioning, Psycholo

1980
Five-day continuous infusion of 5-fluorouracil for advanced colorectal, gastric, and pancreatic adenocarcinoma.
    Journal of surgical oncology, 1979, Volume: 11, Issue:3

    Topics: Adenocarcinoma; Colonic Neoplasms; Drug Administration Schedule; Female; Fluorouracil; Humans; Infus

1979
[Curative aspects of modern combination chemotherapy in generalized malignant lymphomas].
    Schweizerische medizinische Wochenschrift, 1976, May-29, Volume: 106, Issue:22

    Topics: Agranulocytosis; Cyclophosphamide; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Life

1976
A comparison of cyclophosphamide, vincristine, and prednisone (COP) with nitrogen mustard, vincristine, procarbazine, and prednisone (MOPP) in the treatment of nodular, poorly differentiated, lymphocytic lymphoma.
    Cancer, 1976, Volume: 38, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Female; Humans; Lymphoma, Non-Hodgkin; Male; M

1976
Trichlortriethylamine (TS-160 Spofa) in combination chemotherapy of malignant lymphomas.
    Neoplasma, 1975, Volume: 22, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Lymp

1975
MOPP/ABV hybrid program: combination chemotherapy based on early introduction of seven effective drugs for advanced Hodgkin's disease.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:9

    Topics: Actuarial Analysis; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomyc

1985
Procarbazin in advanced malignant melanoma.
    Neoplasma, 1986, Volume: 33, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Female; Humans; Leukopenia; M

1986
[Influencing of side-effects of cytostatic drugs using metoclopramide].
    Munchener medizinische Wochenschrift (1950), 1973, Apr-20, Volume: 115, Issue:16

    Topics: Amides; Anisoles; Antineoplastic Agents; Benzoates; Carcinoma; Ethylamines; Hodgkin Disease; Humans;

1973
Treatment of advanced Hodgkin's disease with combination chemotherapy.
    Southern medical journal, 1973, Volume: 66, Issue:7

    Topics: Adult; Antineoplastic Agents; Dactinomycin; Drug Therapy, Combination; Female; Hodgkin Disease; Huma

1973