procarbazine has been researched along with Metastase in 46 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "40 patients with symptomatic metastatic melanoma were treated with procarbazine, vincristine and lomustine (POC)." | 9.07 | Phase II trial of procarbazine, vincristine and lomustine (POC) chemotherapy in metastatic cutaneous malignant melanoma. ( Evans, BD; Harvey, VJ; Mak, D; Melville, P; Mitchell, PL; Samuel, LM; Thompson, PI, 1994) |
| "Forty-four consecutive ambulatory patients (24 male, 20 female; median age, 56 years [range, 21-76]) with evaluable disseminated malignant melanoma (stages III/IV) were entered in this study from October 1, 1975, to July 21, 1980 (last follow-up, October 31, 1983); they were treated with procarbazine (100 mg/,m2 orally; maximum dose, 150 mg) on Days 1-10, vincristine (1." | 7.67 | Combination cytotoxic chemotherapy with procarbazine, vincristine, and lomustine (POC) in disseminated malignant melanoma: 8 years' follow-up. ( Carmo-Pereira, J; Costa, FO; Henriques, E, 1984) |
| "Sixty-five previously untreated patients with metastatic malignant melanoma were treated with lomustine, vincristine, and procarbazine." | 7.67 | Lomustine, vincristine, and procarbazine in the treatment of metastatic malignant melanoma. ( Bodurtha, A; Iscoe, N; Paterson, A; Quirt, I; Russell, J; Shelley, W; Young, V, 1985) |
| "Twelve previously untreated patients with histologically documented, metastatic, malignant melanoma were treated with the combination of procarbazine, vincristine, CCNU, and cyclophosphamide, with an objective response rate of 33%." | 7.66 | Procarbazine, vincristine, CCNU, and cyclophosphamide (POCC) in the treatment of metastatic malignant melanoma. ( Dillman, RO; Green, MR; Horton, C, 1980) |
| "40 patients with symptomatic metastatic melanoma were treated with procarbazine, vincristine and lomustine (POC)." | 5.07 | Phase II trial of procarbazine, vincristine and lomustine (POC) chemotherapy in metastatic cutaneous malignant melanoma. ( Evans, BD; Harvey, VJ; Mak, D; Melville, P; Mitchell, PL; Samuel, LM; Thompson, PI, 1994) |
| "Forty-four consecutive ambulatory patients (24 male, 20 female; median age, 56 years [range, 21-76]) with evaluable disseminated malignant melanoma (stages III/IV) were entered in this study from October 1, 1975, to July 21, 1980 (last follow-up, October 31, 1983); they were treated with procarbazine (100 mg/,m2 orally; maximum dose, 150 mg) on Days 1-10, vincristine (1." | 3.67 | Combination cytotoxic chemotherapy with procarbazine, vincristine, and lomustine (POC) in disseminated malignant melanoma: 8 years' follow-up. ( Carmo-Pereira, J; Costa, FO; Henriques, E, 1984) |
| "Sixty-five previously untreated patients with metastatic malignant melanoma were treated with lomustine, vincristine, and procarbazine." | 3.67 | Lomustine, vincristine, and procarbazine in the treatment of metastatic malignant melanoma. ( Bodurtha, A; Iscoe, N; Paterson, A; Quirt, I; Russell, J; Shelley, W; Young, V, 1985) |
| "Twelve previously untreated patients with histologically documented, metastatic, malignant melanoma were treated with the combination of procarbazine, vincristine, CCNU, and cyclophosphamide, with an objective response rate of 33%." | 3.66 | Procarbazine, vincristine, CCNU, and cyclophosphamide (POCC) in the treatment of metastatic malignant melanoma. ( Dillman, RO; Green, MR; Horton, C, 1980) |
| "Combination chemotherapy consisting of cyclophosphamide, vincristine, prednisone, and procarbazine (COPP) was administered to 5 patients with invasive lymphoepithelial thymoma." | 3.66 | Combination chemotherapy in invasive thymoma role of COPP. ( Evans, WK; Feld, R; Phillips, MJ; Simpson, WJ; Thompson, DM, 1980) |
| "Sixty two patients with metastases of testicular teratoblastoma were subjected to combination chemotherapy." | 2.65 | [Combined chemotherapy of the metastases of testicular teratoblastomas]. ( Orel, NF, 1979) |
| "Neoadjuvant chemotherapy in Hodgkin's disease has improved survival time and tolerance to irradiation, allowing a lowering of the total doses used and the volumes irradiated." | 1.28 | [Radiotherapy with neoadjuvant chemotherapy]. ( Alapetite, C; Baillet, F; Dessard-Diana, B; Housset, M; Jacquillat, C; Michel-Langlet, P, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (97.83) | 18.7374 |
| 1990's | 1 (2.17) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moser, K | 1 |
| Pohl, A | 1 |
| Bezwoda, WR | 1 |
| Derman, DP | 1 |
| de Moor, NG | 1 |
| Kallenbach, J | 1 |
| Hoffman, PC | 2 |
| Newman, SB | 2 |
| Golomb, HM | 4 |
| Demeester, TR | 3 |
| Blough, RR | 1 |
| Sovik, CA | 1 |
| Carmo-Pereira, J | 1 |
| Costa, FO | 1 |
| Henriques, E | 1 |
| Sampi, K | 1 |
| Honda, T | 1 |
| Hattori, M | 1 |
| Green, MR | 1 |
| Dillman, RO | 1 |
| Horton, C | 1 |
| Evans, WK | 1 |
| Thompson, DM | 1 |
| Simpson, WJ | 1 |
| Feld, R | 1 |
| Phillips, MJ | 1 |
| Samuel, LM | 1 |
| Harvey, VJ | 1 |
| Mitchell, PL | 1 |
| Thompson, PI | 1 |
| Mak, D | 1 |
| Melville, P | 1 |
| Evans, BD | 1 |
| Orel, NF | 1 |
| Sutcliffe, SB | 1 |
| Wrigley, PF | 1 |
| Stansfeld, AG | 1 |
| Malpas, JS | 1 |
| Jacquillat, C | 2 |
| Banzet, P | 1 |
| Civatte, J | 1 |
| Puissant, A | 1 |
| Cottenot, F | 1 |
| Israel, L | 1 |
| Belaich, S | 1 |
| Chastang, C | 1 |
| Maral, J | 1 |
| Bitran, JD | 2 |
| Desser, RK | 2 |
| Colman, M | 1 |
| Evans, R | 1 |
| Billings, A | 1 |
| Griem, M | 1 |
| Rubenstein, L | 1 |
| Shapiro, C | 1 |
| Vinokurov, VL | 1 |
| Vinokurova, NA | 1 |
| Wittes, RE | 1 |
| Wittes, JT | 1 |
| Golbey, RB | 1 |
| Hasegawa, H | 1 |
| Shapiro, WR | 1 |
| Posner, JB | 1 |
| Nordman, EM | 1 |
| Mäntylä, M | 1 |
| Wood, RA | 1 |
| Vogelzang, NJ | 1 |
| Bonomi, PD | 2 |
| Rossof, AH | 1 |
| Wolter, J | 1 |
| Choi, CH | 1 |
| Carey, RW | 1 |
| Weller, SA | 1 |
| Glatstein, E | 1 |
| Kaplan, HS | 2 |
| Rosenberg, SA | 2 |
| Baumgartner, G | 1 |
| Gutin, PH | 1 |
| Wilson, CB | 2 |
| Kumar, AR | 1 |
| Boldrey, EB | 2 |
| Levin, V | 1 |
| Powell, M | 1 |
| Enot, KJ | 2 |
| Van Dyk, JJ | 1 |
| Falkson, G | 1 |
| Baillet, F | 1 |
| Housset, M | 1 |
| Dessard-Diana, B | 1 |
| Michel-Langlet, P | 1 |
| Alapetite, C | 1 |
| Finkelstein, DM | 3 |
| Ruckdeschel, JC | 3 |
| Blum, RH | 1 |
| Green, MD | 1 |
| Mason, B | 1 |
| Hahn, R | 1 |
| Tormey, DC | 1 |
| Harris, J | 1 |
| Comis, R | 1 |
| Roszkowski, K | 1 |
| Nozdryn-Plotnicki, B | 1 |
| Roszkowski, W | 1 |
| Ko, HL | 1 |
| Jeljaszewicz, J | 1 |
| Pulverer, G | 1 |
| Shelley, W | 1 |
| Quirt, I | 1 |
| Bodurtha, A | 1 |
| Iscoe, N | 1 |
| Russell, J | 1 |
| Paterson, A | 1 |
| Young, V | 1 |
| Ettinger, DS | 2 |
| Creech, RH | 1 |
| Mason, BA | 1 |
| Joss, RA | 1 |
| Vogl, S | 1 |
| Carpenter, JT | 1 |
| Raney, M | 1 |
| Logan, T | 1 |
| Shepard, KV | 1 |
| Skosey, C | 1 |
| Bierling, R | 1 |
| Maurer, LH | 3 |
| Tulloh, M | 3 |
| Eagan, RT | 3 |
| Forcier, RJ | 3 |
| House, R | 1 |
| Vasantha Kumar, AR | 1 |
| Renaudin, J | 1 |
| Levin, VA | 1 |
| Alberto, P | 2 |
| Stein, RS | 1 |
| Moran, EM | 1 |
| Miller, JB | 1 |
| Ultmann, JE | 1 |
| Fairley, GH | 1 |
| Freeman, JE | 1 |
| Höffken, K | 1 |
| Hornung, G | 1 |
| Bruntsch, U | 1 |
| Becker, G | 1 |
| Schmidt, CG | 1 |
| Gutterman, JU | 1 |
| Mavligit, G | 1 |
| Gottlieb, JA | 1 |
| Burgess, MA | 1 |
| McBride, CE | 1 |
| Einhorn, L | 1 |
| Freireich, EJ | 1 |
| Hersh, EM | 1 |
| Gamble, JF | 1 |
| Fuller, LM | 1 |
| Butler, JJ | 1 |
| Shullenberger, CC | 1 |
| Moore, MR | 1 |
| Bull, JM | 1 |
| Jones, SE | 1 |
| Arseneau, JC | 1 |
| Sponzo, RW | 1 |
| Levin, DL | 1 |
| Schnipper, LE | 1 |
| Bonner, H | 1 |
| Young, RC | 1 |
| Canellos, GP | 1 |
| Johnson, RE | 1 |
| DeVita, VT | 1 |
| Friedl, HP | 1 |
| Karrer, K | 1 |
| Kühböck, J | 1 |
1 review available for procarbazine and Metastase
| Article | Year |
|---|---|
[Recent developments in chemotherapy of malignant diseases].
Topics: Anthraquinones; Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy | 1982 |
10 trials available for procarbazine and Metastase
| Article | Year |
|---|---|
Metastatic non-small cell bronchogenic carcinoma: a randomized trial of sequential vs combination chemotherapy.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; | 1983 |
Phase II trial of procarbazine, vincristine and lomustine (POC) chemotherapy in metastatic cutaneous malignant melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Lomustine; Male; Melano | 1994 |
[Combined chemotherapy of the metastases of testicular teratoblastomas].
Topics: Adolescent; Adult; Aged; Bleomycin; Choriocarcinoma; Cisplatin; Clinical Trials as Topic; Cyclophosp | 1979 |
[Therapeutic effect of natulan in a recurrence of a granulosa theca cell tumor of the ovaries (1 case)].
Topics: Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Middle Aged; N | 1979 |
Combination chemotherapy in metastatic malignant melanoma: a randomized study of three DTIC-containing combination.
Topics: Adult; Antineoplastic Agents; Clinical Trials as Topic; Cyclophosphamide; Dacarbazine; Drug Therapy, | 1978 |
Combination chemotherapy versus single agents followed by combination chemotherapy in stage IV non-small-cell lung cancer: a study of the Eastern Cooperative Oncology Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cisplat | 1989 |
Small-cell lung cancer and immunochemotherapy with Propionibacterium granulosum KP 45.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Clinical Trials as Top | 1985 |
A randomized trial of the four most active regimens for metastatic non-small-cell lung cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Cyclophos | 1986 |
Combination chemotherapy of lymphomas other than Hodgkin's disease.
Topics: Adolescent; Adult; Aged; Bone Marrow; Bone Marrow Cells; Cyclophosphamide; Drug Therapy, Combination | 1974 |
Sequential radiotherapy and chemotherapy in the treatment of Hodgkin's disease. A progress report.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Benzoates; Child; Drug Combinations; Female; Follow- | 1972 |
35 other studies available for procarbazine and Metastase
| Article | Year |
|---|---|
Treatment of small cell lung cancer: intensive remission induction, radiation therapy, and maintenance chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Small Cell; Doxorubicin; Drug Therap | 1982 |
Combination cytotoxic chemotherapy with procarbazine, vincristine, and lomustine (POC) in disseminated malignant melanoma: 8 years' follow-up.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Follow-Up Studies; Humans; Lomu | 1984 |
[Combination chemotherapy for advanced diffuse non-Hodgkin's lymphomas in relapse following local radiotherapy].
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxo | 1983 |
Procarbazine, vincristine, CCNU, and cyclophosphamide (POCC) in the treatment of metastatic malignant melanoma.
Topics: Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Humans; Lomustine; | 1980 |
Combination chemotherapy in invasive thymoma role of COPP.
Topics: Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Co | 1980 |
Adriamycin, bleomycin, vinblastine and imidazole carboxamide (ABVD) therapy for advanced Hodgkin's disease resistant to mustine, vinblastine, procarbazine and prednisolone (MVPP).
Topics: Adolescent; Adult; Alopecia; Antineoplastic Agents; Bleomycin; Child; Doxorubicin; Drug Administrati | 1979 |
Adjuvant chemotherapy or chemoimmunotherapy in the management of primary malignant melanoma of level III, IV, or V.
Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Bacterial Vaccines; BCG Vaccine; Dacarbazine; Drug | 1978 |
Cyclophosphamide, adriamycin, methotrexate, and procarbazine (CAMP)--effective four-drug combination chemotherapy for metastatic non-oat cell bronchogenic carcinoma.
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adult; Aged; Bone Neoplasms; Brain Neoplasms; C | 1976 |
Chemotherapy of experimental metastatic brain tumors in female Wistar rats.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carcinoma 256, Walker; Carotid Arteries; Cells, Cul | 1979 |
Treatment of metastatic melanoma with combined 5-fluorouracil and procarbazine.
Topics: Adult; Aged; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Melanoma; Middle Aged; N | 1977 |
If I had Hodgkin's disease.
Topics: Drug Therapy, Combination; Hodgkin Disease; Humans; Neoplasm Metastasis; Neoplasm Staging; Nitrogen | 1978 |
Cyclophosphamide, adriamycin, methotrexate, and procarbazine (CAMP) treatment of non-oat cell bronchogenic carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Bronchogenic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combina | 1978 |
Small cell anaplastic carcinoma of lung. Reappraisal of current management.
Topics: Adult; Aged; Carcinoma; Cyclophosphamide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplas | 1976 |
Initial relapses in previously treated Hodgkin's disease. I. Results of second treatment.
Topics: Female; Hodgkin Disease; Humans; Male; Mechlorethamine; Neoplasm Metastasis; Neoplasm Recurrence, Lo | 1976 |
[Cytostatic therapy of inoperable carcinomas].
Topics: Breast Neoplasms; Bronchial Neoplasms; Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin | 1976 |
Phase II study of procarbazine, CCNU, and vincristine combination chemotherapy in the treatment of malignant brain tumors.
Topics: Brain Neoplasms; Drug Therapy, Combination; Evaluation Studies as Topic; Humans; Lomustine; Neoplasm | 1975 |
A clinical trial of procarbazine plus vincristine plus bis-chloroethyl-nitrosourea plus imidazole carboxamide dimethyl triazeno in metastatic malignant melanoma.
Topics: Adult; Aged; Carmustine; Dacarbazine; Drug Therapy, Combination; Female; Humans; Liver Neoplasms; Lu | 1975 |
[Radiotherapy with neoadjuvant chemotherapy].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Doxorub | 1989 |
Lomustine, vincristine, and procarbazine in the treatment of metastatic malignant melanoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Hematologic Diseases; Humans; L | 1985 |
Long-term survivors in metastatic non-small-cell lung cancer: an Eastern Cooperative Oncology Group Study.
Topics: Adenocarcinoma; Aged; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Body Wei | 1986 |
Phase II evaluation of procarbazine in metastatic breast cancer: a Southeastern Cancer Study Group Trial.
Topics: Adult; Aged; Breast Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Gastrointestin | 1986 |
CAMP chemotherapy for metastatic non-oat cell bronchogenic carcinoma. A 7-year experience (1975-1981) with 160 patients.
Topics: Actuarial Analysis; Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Car | 1985 |
Experimental investigations on problems of the clinical use of L-asparaginase.
Topics: Animals; Antibody Formation; Antineoplastic Agents; Asparaginase; Cytarabine; Dactinomycin; Drug Res | 1970 |
Combination chemotherapy and radiation therapy for small cell carcinoma of the lung.
Topics: Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cyclophosphamide; Humans; Lung Neoplasms; Methotrexa | 1973 |
Procarbazine hydrochloride in the treatment of brain tumors. Phase 2 study.
Topics: Adolescent; Adult; Anticonvulsants; Astrocytoma; Brain Neoplasms; Child; Electroencephalography; Epe | 1974 |
[Prognostic factors in the chemotherapy of bronchial cancers].
Topics: Adenocarcinoma; Age Factors; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma; Carcinoma, Bronc | 1974 |
Blood and neoplastic diseases. Treatment of the lymphomas.
Topics: Alopecia; Bone Marrow; Cyclophosphamide; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Follicular; Ne | 1974 |
[Treatment of Hodgkin's disease of the stomach].
Topics: Adult; Cyclophosphamide; Female; Hodgkin Disease; Humans; Male; Middle Aged; Neoplasm Metastasis; Pr | 1973 |
Combination chemotherapy and radiation therapy in small cell carcinoma of the lung.
Topics: Adult; Aged; Bone Marrow; Carcinoma, Bronchogenic; Cyclophosphamide; Evaluation Studies as Topic; Fe | 1973 |
Remission rates, survival, and prognostic factors in combination chemotherapy for bronchogenic carcinoma.
Topics: Carcinoma, Bronchogenic; Cyclophosphamide; Humans; Lung Neoplasms; Methotrexate; Neoplasm Metastasis | 1973 |
Proceedings: Small cell carcinoma of the lung: staging, paraneoplastic syndromes, treatment, and survival.
Topics: Bone Marrow; Bone Neoplasms; Brain Neoplasms; Carcinoma; Cyclophosphamide; Drug Therapy, Combination | 1974 |
Chemoimmunotherapy of disseminated malignant melanoma with dimethyl triazeno imidazole carboxamide and bacillus calmette--guérin.
Topics: Adult; Aged; Amides; Antibody Formation; Antineoplastic Agents; BCG Vaccine; Carmustine; Drug Therap | 1974 |
Combined chemotherapy and radiotherapy for advanced Hodgkin's disease and reticulum cell sarcoma: a preliminary report.
Topics: Adolescent; Adult; Aged; Blood Cell Count; Cyclophosphamide; Female; Hodgkin Disease; Humans; Lympho | 1971 |
Nonlymphomatous malignant tumors complicating Hodgkin's disease. Possible association with intensive therapy.
Topics: Adolescent; Adult; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Drug-Related S | 1972 |
The relation of tumour size to the results of chemotherapy in malignant tumours.
Topics: Amputation, Surgical; Animals; Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Mercaptopurine | 1971 |