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procarbazine and Malignant Melanoma

procarbazine has been researched along with Malignant Melanoma in 38 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Research Excerpts

ExcerptRelevanceReference
"The aim of this randomized four-arm phase III study was to evaluate whether there is a difference in activity between regimens containing dacarbazine and regimens without dacarbazine in metastatic melanoma, whether there is a dose-effect relationship for dacarbazine, and whether non-dacarbazine-containing aggressive regimens are in any way superior to non-aggressive ones."9.10Comparison of the efficacy of two different dosage dacarbazine-based regimens and two regimens without dacarbazine in metastatic melanoma: a single-centre randomized four-arm study. ( Babovic, N; Jelić, S; Kovcin, V; Milanovic, N; Milicevic, N; Popov, I; Radosavljevic, D, 2002)
"40 patients with symptomatic metastatic melanoma were treated with procarbazine, vincristine and lomustine (POC)."9.07Phase II trial of procarbazine, vincristine and lomustine (POC) chemotherapy in metastatic cutaneous malignant melanoma. ( Evans, BD; Harvey, VJ; Mak, D; Melville, P; Mitchell, PL; Samuel, LM; Thompson, PI, 1994)
"Forty-three patients with measurable disseminated cutaneous malignant melanoma, stages III-IV, and without previous cytotoxic chemotherapy or immunotherapy, were randomly allocated from 30 June 1980 to 30 November 1984, to receive either a schedule of procarbazine (100 mg/m2 p."9.06Cytotoxic chemotherapy of disseminated cutaneous malignant melanoma--a prospective and randomized clinical trial of procarbazine, vindesine and lomustine versus procarbazine, DTIC and lomustine. ( Carmo-Pereira, J; Costa, FO; Henriques, E, 1986)
"Patients with stage III and IV melanoma were randomly assigned to receive procarbazine (100 mg/m2, Days 1--10), vinblastine (5 mg/m2, Days 1 and 8), and actinomycin D (0."9.04Procarbazine, vinblastine, and actinomycin D in stage III and IV melanoma with or without methanol-extracted residue of Bacillus Calmette-Guérin. ( Cuttner, J; De Bellis, R; Green, M; Kostinas, JE; Leone, LA; Pajak, TF; Vinciguerra, V, 1979)
"Patients with advanced malignant melanoma were randomly assigned to treatment with cylcophosphamide and vincristine (CV) or cyclophosphamide, vincristine, and procarbazine (CVP)."9.04Cyclophosphamide, vincristine and procarbazine in the treatment of malignant melanoma. ( Byrne, MJ, 1976)
"Forty-four consecutive ambulatory patients (24 male, 20 female; median age, 56 years [range, 21-76]) with evaluable disseminated malignant melanoma (stages III/IV) were entered in this study from October 1, 1975, to July 21, 1980 (last follow-up, October 31, 1983); they were treated with procarbazine (100 mg/,m2 orally; maximum dose, 150 mg) on Days 1-10, vincristine (1."7.67Combination cytotoxic chemotherapy with procarbazine, vincristine, and lomustine (POC) in disseminated malignant melanoma: 8 years' follow-up. ( Carmo-Pereira, J; Costa, FO; Henriques, E, 1984)
"Twenty-one patients with metastatic melanoma were treated synchronously with procarbazine and radiotherapy."7.67Effective palliation of melanoma with procarbazine and radiotherapy given by a low-dose fractionation schedule. ( Abbott, RL; Ahmad, A; Gill, PG; Zeicmanis, J, 1986)
"Sixty-five previously untreated patients with metastatic malignant melanoma were treated with lomustine, vincristine, and procarbazine."7.67Lomustine, vincristine, and procarbazine in the treatment of metastatic malignant melanoma. ( Bodurtha, A; Iscoe, N; Paterson, A; Quirt, I; Russell, J; Shelley, W; Young, V, 1985)
"Fourteen consecutive melanoma patients with evaluable metastatic disease were treated with combination chemotherapy including procarbazine, vincristine and lomustine (POC)."7.67Metastatic malignant melanoma treated with procarbazine, vincristine and lomustine (POC). ( Ardizzoni, A; Grimaldi, A; Repetto, L; Rosso, R; Sertoli, MR, 1987)
"Twelve previously untreated patients with histologically documented, metastatic, malignant melanoma were treated with the combination of procarbazine, vincristine, CCNU, and cyclophosphamide, with an objective response rate of 33%."7.66Procarbazine, vincristine, CCNU, and cyclophosphamide (POCC) in the treatment of metastatic malignant melanoma. ( Dillman, RO; Green, MR; Horton, C, 1980)
"Thirty patients with disseminated cutaneous malignant melanoma were treated with a three-drug cytotoxic chemotherapy program consisting of CCNU, procarbazine, and vincristine."7.66Combination cytotoxic chemotherapy with CCNU, procarbazine, and vincristine in disseminated cutaneous malignant melanoma: 3 years, followup. ( Carmo-Pereira, J; Costa, FO; Henriques, E; Pimentel, P, 1980)
"The aim of this randomized four-arm phase III study was to evaluate whether there is a difference in activity between regimens containing dacarbazine and regimens without dacarbazine in metastatic melanoma, whether there is a dose-effect relationship for dacarbazine, and whether non-dacarbazine-containing aggressive regimens are in any way superior to non-aggressive ones."5.10Comparison of the efficacy of two different dosage dacarbazine-based regimens and two regimens without dacarbazine in metastatic melanoma: a single-centre randomized four-arm study. ( Babovic, N; Jelić, S; Kovcin, V; Milanovic, N; Milicevic, N; Popov, I; Radosavljevic, D, 2002)
"40 patients with symptomatic metastatic melanoma were treated with procarbazine, vincristine and lomustine (POC)."5.07Phase II trial of procarbazine, vincristine and lomustine (POC) chemotherapy in metastatic cutaneous malignant melanoma. ( Evans, BD; Harvey, VJ; Mak, D; Melville, P; Mitchell, PL; Samuel, LM; Thompson, PI, 1994)
"Forty-three patients with measurable disseminated cutaneous malignant melanoma, stages III-IV, and without previous cytotoxic chemotherapy or immunotherapy, were randomly allocated from 30 June 1980 to 30 November 1984, to receive either a schedule of procarbazine (100 mg/m2 p."5.06Cytotoxic chemotherapy of disseminated cutaneous malignant melanoma--a prospective and randomized clinical trial of procarbazine, vindesine and lomustine versus procarbazine, DTIC and lomustine. ( Carmo-Pereira, J; Costa, FO; Henriques, E, 1986)
"Patients with stage III and IV melanoma were randomly assigned to receive procarbazine (100 mg/m2, Days 1--10), vinblastine (5 mg/m2, Days 1 and 8), and actinomycin D (0."5.04Procarbazine, vinblastine, and actinomycin D in stage III and IV melanoma with or without methanol-extracted residue of Bacillus Calmette-Guérin. ( Cuttner, J; De Bellis, R; Green, M; Kostinas, JE; Leone, LA; Pajak, TF; Vinciguerra, V, 1979)
"Patients with advanced malignant melanoma were randomly assigned to treatment with cylcophosphamide and vincristine (CV) or cyclophosphamide, vincristine, and procarbazine (CVP)."5.04Cyclophosphamide, vincristine and procarbazine in the treatment of malignant melanoma. ( Byrne, MJ, 1976)
"Forty-four consecutive ambulatory patients (24 male, 20 female; median age, 56 years [range, 21-76]) with evaluable disseminated malignant melanoma (stages III/IV) were entered in this study from October 1, 1975, to July 21, 1980 (last follow-up, October 31, 1983); they were treated with procarbazine (100 mg/,m2 orally; maximum dose, 150 mg) on Days 1-10, vincristine (1."3.67Combination cytotoxic chemotherapy with procarbazine, vincristine, and lomustine (POC) in disseminated malignant melanoma: 8 years' follow-up. ( Carmo-Pereira, J; Costa, FO; Henriques, E, 1984)
"Twenty-one patients with metastatic melanoma were treated synchronously with procarbazine and radiotherapy."3.67Effective palliation of melanoma with procarbazine and radiotherapy given by a low-dose fractionation schedule. ( Abbott, RL; Ahmad, A; Gill, PG; Zeicmanis, J, 1986)
"Sixty-five previously untreated patients with metastatic malignant melanoma were treated with lomustine, vincristine, and procarbazine."3.67Lomustine, vincristine, and procarbazine in the treatment of metastatic malignant melanoma. ( Bodurtha, A; Iscoe, N; Paterson, A; Quirt, I; Russell, J; Shelley, W; Young, V, 1985)
"Fourteen consecutive melanoma patients with evaluable metastatic disease were treated with combination chemotherapy including procarbazine, vincristine and lomustine (POC)."3.67Metastatic malignant melanoma treated with procarbazine, vincristine and lomustine (POC). ( Ardizzoni, A; Grimaldi, A; Repetto, L; Rosso, R; Sertoli, MR, 1987)
"Single-cell suspensions prepared from five human melanomas, grown serially as xenografts in athymic nude mice, were exposed in vitro to increasing concentrations of DTIC (Dacarbazine), CCNU (Lomustine), procarbazine, vinblastine, and the cancerostatic lectins abrin and ricin."3.66In vitro sensitivity of human melanoma xenografts to cytotoxic drugs. Correlation with in vivo chemosensitivity. ( Fodstad, O; Olsnes, S; Pihl, A; Tveit, KM, 1980)
"Twelve previously untreated patients with histologically documented, metastatic, malignant melanoma were treated with the combination of procarbazine, vincristine, CCNU, and cyclophosphamide, with an objective response rate of 33%."3.66Procarbazine, vincristine, CCNU, and cyclophosphamide (POCC) in the treatment of metastatic malignant melanoma. ( Dillman, RO; Green, MR; Horton, C, 1980)
"Thirty patients with disseminated cutaneous malignant melanoma were treated with a three-drug cytotoxic chemotherapy program consisting of CCNU, procarbazine, and vincristine."3.66Combination cytotoxic chemotherapy with CCNU, procarbazine, and vincristine in disseminated cutaneous malignant melanoma: 3 years, followup. ( Carmo-Pereira, J; Costa, FO; Henriques, E; Pimentel, P, 1980)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199034 (89.47)18.7374
1990's2 (5.26)18.2507
2000's2 (5.26)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gasowska-Bajger, B1
Wojtasek, H1
TODD, ID1
Stragand, JJ1
Drewinko, B1
Barlogie, B1
Papadopoulous, N1
White, RA1
Carmo-Pereira, J3
Costa, FO3
Henriques, E3
Jacquillat, C3
Banzet, P2
Maral, J3
Tveit, KM2
Fodstad, O4
Olsnes, S1
Pihl, A4
Aass, N2
Green, MR1
Dillman, RO1
Horton, C1
Pimentel, P1
Samuel, LM1
Harvey, VJ1
Mitchell, PL1
Thompson, PI1
Mak, D1
Melville, P1
Evans, BD1
Jelić, S1
Babovic, N1
Kovcin, V1
Milicevic, N1
Milanovic, N1
Popov, I1
Radosavljevic, D1
Schneider, I1
Aulepp, H1
Gartmann, H1
Civatte, J1
Puissant, A1
Cottenot, F1
Israel, L1
Belaich, S1
Chastang, C1
Volm, M2
Faufmann, M1
MAttern, J2
Wayss, K2
Wilson, CB1
Gutin, P1
Boldrey, EB1
Drafts, D1
Levin, VA1
Enot, KJ1
Carl, W1
Wittes, RE1
Wittes, JT1
Golbey, RB1
Kostinas, JE1
Leone, LA1
Cuttner, J1
Vinciguerra, V1
Green, M1
De Bellis, R1
Pajak, TF1
Kolarić, K1
Malenica, B1
Roth, A1
Nordman, EM1
Mäntylä, M1
Didolkar, MS1
Baffi, RR1
Catane, R1
Kaufman, J1
Holyoke, ED1
Byrne, MJ1
Van Dyk, JJ1
Falkson, G1
Glover, DJ1
Gill, PG1
Abbott, RL1
Ahmad, A1
Zeicmanis, J1
Wang, QL1
Shelley, W1
Quirt, I1
Bodurtha, A1
Iscoe, N1
Russell, J1
Paterson, A1
Young, V1
Repetto, L1
Grimaldi, A1
Ardizzoni, A1
Sertoli, MR1
Rosso, R1
Dobrek, Z1
Sellami, M1
Weil, M1
Auclerc, G1
Dhermy, P1
Aron-Rosa, D1
Mechl, Z1
Krejcí, P1
Bonadonna, G1
De Lena, M1
Banfi, A1
Lattuada, A1
Luce, JK1
Gutterman, JU1
Mavligit, G1
Gottlieb, JA1
Burgess, MA1
McBride, CE1
Einhorn, L1
Freireich, EJ1
Hersh, EM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Does Varenicline Influence Alcohol Consumption in Alcohol Dependent Individuals?[NCT00846859]Phase 2162 participants (Actual)Interventional2009-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for procarbazine and Malignant Melanoma

ArticleYear
Chemotherapy of malignant melanoma.
    Cancer, 1972, Volume: 30, Issue:6

    Topics: Alkylating Agents; Amides; Animals; Antigen-Antibody Reactions; Antimetabolites; Antineoplastic Agen

1972

Trials

8 trials available for procarbazine and Malignant Melanoma

ArticleYear
Clinical trials of chemotherapy and chemoimmunotherapy in primary malignant melanoma.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1982, Volume: 80

    Topics: Clinical Trials as Topic; Dacarbazine; Drug Administration Schedule; Drug Therapy, Combination; Fema

1982
Phase II trial of procarbazine, vincristine and lomustine (POC) chemotherapy in metastatic cutaneous malignant melanoma.
    European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:14

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Lomustine; Male; Melano

1994
Comparison of the efficacy of two different dosage dacarbazine-based regimens and two regimens without dacarbazine in metastatic melanoma: a single-centre randomized four-arm study.
    Melanoma research, 2002, Volume: 12, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Dacarbazine; Dose-Response

2002
Combination chemotherapy in metastatic malignant melanoma: a randomized study of three DTIC-containing combination.
    Cancer, 1978, Volume: 41, Issue:2

    Topics: Adult; Antineoplastic Agents; Clinical Trials as Topic; Cyclophosphamide; Dacarbazine; Drug Therapy,

1978
Procarbazine, vinblastine, and actinomycin D in stage III and IV melanoma with or without methanol-extracted residue of Bacillus Calmette-Guérin.
    Cancer treatment reports, 1979, Volume: 63, Issue:2

    Topics: Antineoplastic Agents; BCG Vaccine; Bone Marrow; Clinical Trials as Topic; Dactinomycin; Digestive S

1979
Cyclophosphamide, vincristine and procarbazine in the treatment of malignant melanoma.
    Cancer, 1976, Volume: 38, Issue:5

    Topics: Adult; Aged; Clinical Trials as Topic; Cyclophosphamide; Dacarbazine; Drug Therapy, Combination; Fem

1976
Cytotoxic chemotherapy of disseminated cutaneous malignant melanoma--a prospective and randomized clinical trial of procarbazine, vindesine and lomustine versus procarbazine, DTIC and lomustine.
    European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Drug Evaluation; Female; H

1986
[Clinical trials of chemotherapy and chemoimmunotherapy of malignant melanoma with unfavorable prognosis after surgical treatment].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1985, Feb-15, Volume: 38, Issue:4

    Topics: Adjuvants, Immunologic; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical

1985

Other Studies

29 other studies available for procarbazine and Malignant Melanoma

ArticleYear
Indirect oxidation of the antitumor agent procarbazine by tyrosinase--possible application in designing anti-melanoma prodrugs.
    Bioorganic & medicinal chemistry letters, 2008, Jun-01, Volume: 18, Issue:11

    Topics: Agaricales; Antineoplastic Agents; Hydrazines; Melanoma; Molecular Structure; Monophenol Monooxygena

2008
NATULAN IN MANAGEMENT OF LATE HODGKIN'S DISEASE, OTHER LYMPHORETICULAR NEOPLASMS, AND MALIGNANT MELANOMA.
    British medical journal, 1965, Mar-06, Volume: 1, Issue:5435

    Topics: Antineoplastic Agents; Drug Therapy; Hodgkin Disease; Humans; Hydrazines; Lymphoma; Lymphoma, Follic

1965
Serial analysis of melanoma growth kinetics in a patient receiving bleomycin and procarbazine therapy: comparison of tumor volume, flow cytometry, and thymidine labeling techniques.
    Cancer treatment reports, 1982, Volume: 66, Issue:3

    Topics: Autoradiography; Bleomycin; Cell Division; DNA, Neoplasm; Female; Flow Cytometry; Humans; Melanoma;

1982
Combination cytotoxic chemotherapy with procarbazine, vincristine, and lomustine (POC) in disseminated malignant melanoma: 8 years' follow-up.
    Cancer treatment reports, 1984, Volume: 68, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Follow-Up Studies; Humans; Lomu

1984
In vitro sensitivity of human melanoma xenografts to cytotoxic drugs. Correlation with in vivo chemosensitivity.
    International journal of cancer, 1980, Dec-15, Volume: 26, Issue:6

    Topics: Abrin; Animals; Antineoplastic Agents; Dacarbazine; Humans; Lomustine; Melanoma; Mice; Mice, Nude; N

1980
The usefulness of human tumor cell lines in the study of chemosensitivity. A study of malignant melanomas.
    International journal of cancer, 1981, Oct-15, Volume: 28, Issue:4

    Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Dacarbazine; Drug Evaluation, Preclinical;

1981
Response to chemotherapy of human, malignant melanoma xenografts in athymic, nude mice.
    International journal of cancer, 1980, Apr-15, Volume: 25, Issue:4

    Topics: Abrin; Animals; Antineoplastic Agents; Dacarbazine; Humans; Lomustine; Melanoma; Mice; Mice, Nude; N

1980
Procarbazine, vincristine, CCNU, and cyclophosphamide (POCC) in the treatment of metastatic malignant melanoma.
    Cancer treatment reports, 1980, Volume: 64, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Humans; Lomustine;

1980
Combination cytotoxic chemotherapy with CCNU, procarbazine, and vincristine in disseminated cutaneous malignant melanoma: 3 years, followup.
    Cancer treatment reports, 1980, Volume: 64, Issue:1

    Topics: Adult; Aged; Female; Follow-Up Studies; Humans; Leukopenia; Lomustine; Male; Melanoma; Middle Aged;

1980
An inverse relationship between the growth rate of human melanoma xenografts and their response to some cytostatic drugs.
    British journal of cancer, 1980, Volume: 41, Issue:5

    Topics: Animals; Dacarbazine; Humans; Lomustine; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Neopl

1980
[Histological and histochemical studies on melanoma metastases under immunobiological and cytostatic therapy].
    Zeitschrift fur Hautkrankheiten, 1976, Feb-01, Volume: 51, Issue:3

    Topics: Antineoplastic Agents; BCG Vaccine; Bleomycin; Cytarabine; Dinitrochlorobenzene; Fluorouracil; Human

1976
Adjuvant chemotherapy or chemoimmunotherapy in the management of primary malignant melanoma of level III, IV, or V.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1978, Volume: 68

    Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Bacterial Vaccines; BCG Vaccine; Dacarbazine; Drug

1978
Sensitivity tests of tumors to cytostatic agents. I. Comparative investigations on transplanted tumors in vivo and in vitro.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1975, Volume: 83, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cell Division; Cricetinae; Da

1975
Single-agent chemotherapy of brain tumors. A five-year review.
    Archives of neurology, 1976, Volume: 33, Issue:11

    Topics: Astrocytoma; Bone Marrow Diseases; Brain Neoplasms; Carmustine; Glioma; Humans; Imidazoles; Lomustin

1976
Cancer chemotherapy and dentistry.
    Quintessence international, dental digest, 1977, Volume: 8, Issue:12

    Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Asparaginase; Carci

1977
A preliminary report of a pilot trial in adjuvant chemotherapy of primary melanoma.
    Tumori, 1979, Apr-30, Volume: 65, Issue:2

    Topics: Antineoplastic Agents; BCG Vaccine; Dacarbazine; Dactinomycin; Drug Therapy, Combination; Female; Hu

1979
Treatment of metastatic melanoma with combined 5-fluorouracil and procarbazine.
    Cancer treatment reports, 1977, Volume: 61, Issue:9

    Topics: Adult; Aged; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male; Melanoma; Middle Aged; N

1977
Use of methyl-CCNU and procarbazine in advanced malignant melanoma resistant to DTIC therapy.
    Cancer treatment reports, 1977, Volume: 61, Issue:9

    Topics: Dacarbazine; Drug Evaluation; Drug Resistance; Humans; Melanoma; Nitrosourea Compounds; Procarbazine

1977
A clinical trial of procarbazine plus vincristine plus bis-chloroethyl-nitrosourea plus imidazole carboxamide dimethyl triazeno in metastatic malignant melanoma.
    Medical and pediatric oncology, 1975, Volume: 1, Issue:2

    Topics: Adult; Aged; Carmustine; Dacarbazine; Drug Therapy, Combination; Female; Humans; Liver Neoplasms; Lu

1975
New approaches to the chemotherapy of melanoma.
    Oncology (Williston Park, N.Y.), 1991, Volume: 5, Issue:5

    Topics: Alkaloids; Amifostine; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Proto

1991
Effective palliation of melanoma with procarbazine and radiotherapy given by a low-dose fractionation schedule.
    The Medical journal of Australia, 1986, Feb-03, Volume: 144, Issue:3

    Topics: Brain Neoplasms; Combined Modality Therapy; Humans; Lymphatic Metastasis; Male; Melanoma; Palliative

1986
[Various doses cisplatin combined with multi-drug chemotherapy of malignant solid tumors].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1989, Volume: 11, Issue:3

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neop

1989
Lomustine, vincristine, and procarbazine in the treatment of metastatic malignant melanoma.
    Cancer treatment reports, 1985, Volume: 69, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Hematologic Diseases; Humans; L

1985
Metastatic malignant melanoma treated with procarbazine, vincristine and lomustine (POC).
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Female

1987
[Adjuvant chemotherapy of intraocular malignant melanoma. Apropos of 20 cases].
    Journal francais d'ophtalmologie, 1985, Volume: 8, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy;

1985
Procarbazin in advanced malignant melanoma.
    Neoplasma, 1986, Volume: 33, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Female; Humans; Leukopenia; M

1986
Secondary neoplasms in malignant lymphomas after intensive therapy.
    The New England journal of medicine, 1973, Jun-07, Volume: 288, Issue:23

    Topics: Adult; Antineoplastic Agents; Follow-Up Studies; Hodgkin Disease; Humans; Leukemia, Myeloid, Acute;

1973
Chemoimmunotherapy of disseminated malignant melanoma with dimethyl triazeno imidazole carboxamide and bacillus calmette--guérin.
    The New England journal of medicine, 1974, Sep-19, Volume: 291, Issue:12

    Topics: Adult; Aged; Amides; Antibody Formation; Antineoplastic Agents; BCG Vaccine; Carmustine; Drug Therap

1974
The effects of cytostatic drugs on transplanted tumours. An investigation of the correlation between in vivo and in vitro results.
    Archiv fur Geschwulstforschung, 1974, Volume: 43, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cricetinae; Cytarabine; Dauno

1974