procarbazine has been researched along with Lymphoma, Large B-Cell, Diffuse in 87 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Lymphoma, Large B-Cell, Diffuse: Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. The pattern is predominantly diffuse. Most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the clinical effects of high-dose methotrexate(HD-MTX)combined with rituximab and vincristine in 5 elderly patients, aged 65-83 years, with diffuse large B-cell lymphoma of the central nervous system(DLBCL CNS)." | 7.85 | [Clinical Analysis of Combination Chemotherapy Using High Dose Methotrexate, Rituximab, and Vincristine with or without Procarbazine for Elderly Patients with Diffuse Large B-Cell Lymphoma of the Central Nervous System]. ( Goto, T; Nagura, E; Nakashima, M; Okamoto, S; Tanaka, M, 2017) |
| "Sixty-seven evaluable patients with mixed cellular and histiocytic lymphomas, both nodular and diffuse, were treated with a combined drug regimen of BCNU, cyclophosphamide, vincristine, and prednisone administered for six monthly courses." | 7.65 | 1,3-bis(2-chloroethyl)-1-nitrosourea(BCNU), cyclophosphamide, vincristine- and prednisone-(BCOP). A new therapeutic regimen for diffuse histiocytic lymphoma. ( Chan, YK; Dorfman, R; Durant, JR; Loeb, V, 1975) |
| "45%, respectively, in Hodgkin's disease, and 85% vs." | 5.25 | Combined cyclophosphamide vincristine, procarbazine, and prednisone (COPP) therapy of malignant lymphoma. Evaluation of 190 patients. ( Barros, CA; Morgenfeld, MC; Palau, M; Pavlovsky, A; Pavlovsky, S; Somoza, N; Suarez, A, 1975) |
| "We studied the clinical effects of high-dose methotrexate(HD-MTX)combined with rituximab and vincristine in 5 elderly patients, aged 65-83 years, with diffuse large B-cell lymphoma of the central nervous system(DLBCL CNS)." | 3.85 | [Clinical Analysis of Combination Chemotherapy Using High Dose Methotrexate, Rituximab, and Vincristine with or without Procarbazine for Elderly Patients with Diffuse Large B-Cell Lymphoma of the Central Nervous System]. ( Goto, T; Nagura, E; Nakashima, M; Okamoto, S; Tanaka, M, 2017) |
| "In the histiocytic lymphomas, BCNU added to CVP increases the percentage of CRs but it does so at the expense of considerable toxicity." | 3.74 | Chemotherapy of non-Hodgkin's lymphomas: Eastern Cooperative Oncology Group experience. ( Bennett, JM; Carbone, PP; Ezdinli, E; Johnson, GJ; Lenhard, RE; Pocock, SJ, 1977) |
| "Sixty-seven evaluable patients with mixed cellular and histiocytic lymphomas, both nodular and diffuse, were treated with a combined drug regimen of BCNU, cyclophosphamide, vincristine, and prednisone administered for six monthly courses." | 3.65 | 1,3-bis(2-chloroethyl)-1-nitrosourea(BCNU), cyclophosphamide, vincristine- and prednisone-(BCOP). A new therapeutic regimen for diffuse histiocytic lymphoma. ( Chan, YK; Dorfman, R; Durant, JR; Loeb, V, 1975) |
| "The response rate and survival in diffuse histiocytic lymphoma have improved since the first study." | 2.64 | Chemotherapy of non-Hodgkin's lymphoma: 10 years' experience in the Southwest Oncology Group. ( Coltman, CA; Jones, SE; Luce, JK; McKelvey, EM; Moon, TE, 1977) |
| "Waldenström's macroglobulinemia (WM) is a neoplasm of lymphoplasmacytic cells that produces monoclonal IgM protein." | 1.42 | Successful Treatment of Bing-Neel Syndrome Accompanying Waldenström's Macroglobulinemia with R-MPV: A Case Report. ( Endo, S; Hata, H; Kawano, Y; Kikukawa, Y; Mitsuya, H; Miyagawa, E; Okuno, Y; Ueno, S; Yamamura-Fujimoto, A, 2015) |
| "Grade 3 follicular lymphoma (FL3) is thought to have an aggressive clinical course." | 1.32 | A significant diffuse component predicts for inferior survival in grade 3 follicular lymphoma, but cytologic subtypes do not predict survival. ( Aoun, P; Armitage, JO; Bierman, PJ; Bociek, RG; Chan, WC; Greiner, TC; Hans, CP; Hock, LM; Lynch, JC; Vose, JM; Weisenburger, DD, 2003) |
| "Spinal cord compression has been reported in 5% of patients with solid tumors." | 1.29 | [Spinal cord compression as the presenting form of non-Hodgkin's lymphoma]. ( Amigo, ML; Caballero, D; del Cañizo, C; Revilla, R; San Miguel, JF; Sánchez, C, 1995) |
| "Procarbazine and BCNU were given for 5 months before conception and throughout the first and second trimesters, and streptozotocin was given throughout the third trimester." | 1.27 | Successful pregnancy following continuous treatment with combination chemotherapy before conception and throughout pregnancy. ( Chudley, AE; Schapira, DV, 1984) |
| "Long-term survivors of advanced diffuse histiocytic lymphoma treated with comparable chemotherapy, who served as a control population, had significantly higher percentages of E rosettes and no reduction in mitogen-induced lymphocyte proliferation." | 1.26 | Persistent immunologic abnormalities in long-term survivors of advanced Hodgkin's disease. ( Bostick, F; DeVita, VT; Fisher, RI; Howser, DM; Hubbard, SM; Vanhaelen, C; Young, RC, 1980) |
| "A patient with histiocytic lymphoma had abdominal masses, hypophosphatemia, normocalcemia, and a normal serum parathyroid hormone value." | 1.26 | Hypophosphatemia in a patient with lymphoma in leukemic phase. ( Matzner, Y; Polliack, A; Popovtzer, MM; Prococimer, M; Rubinger, D, 1981) |
| "15 patients with malignant lymphomas (stage III B or IV) who had become resistant to previous combination chemotherapy were treated with DTIC." | 1.26 | Imidazole carboxamide (DTIC) in the treatment of advanced lymphomas. Efficacy of DTIC in cases which fail to respond to conventional chemotherupetic combinations. ( Donner, L; Klener, P, 1977) |
| "Fifteen patients with stage III and IV diffuse histiocytic lymphoma were treated with combination chemotherapy: cyclophosphamide, vincristine sulfate, prednisone, and procarbazine hydrochloride (COPP)." | 1.26 | Diffuse histiocytic lymphoma. The need for aggressive restaging. ( Babick, T; Levitt, M; Weinerman, BH, 1977) |
| "For patients with lymphosarcoma the average duration of complete remission was 26." | 1.26 | [Polychemotherapy in non-hodgkin lymphoma with a modified MOPP scheme (author's transl)]. ( Hiller, E; Schmülling, RM; Tigges, FJ; Waller, HD; Wilms, K, 1977) |
| "Twenty-seven patients with advanced diffuse histiocytic lymphoma (reticulum-cell sarcoma) were treated with combination chemotherapy utilising nitrogen mustard (or cyclophosphamide), procarbazine, vincristine, and prednisone." | 1.25 | Advanced diffuse histiocytic lymphoma, a potentially curable disease. ( Canellos, GP; Chabner, B; DeVita, VT; Hubbard, SP; Schein, P; Young, RC, 1975) |
| "The survival was longer for nodular lymphosarcoma patients (25% are alive at 7 years for Stages III and IV) than for diffuse lymphosarcomata and reticulosarcomata (10%)." | 1.25 | Non-Hodgkin's malignant lymphomata in adults: chemo-radiotherapy in stages III and IV. ( Amiel, JL; Hayat, M; Mathé, G; Pouillart, P; Schwarzenberg, L; Tubiana, M, 1975) |
| "Patients with diffuse histiocytic lymphoma who achieved a histologically proven complete remission after 6 months of treatment without maintenance have remained disease-free whereas those with nodular poorly differentiated lymphocytic and diffuse well-differentiated lymphocytic lymphomas have demonstrated a pattern of continuous late recurrence." | 1.25 | Non-Hodgkin's lymphoma: patterns of relapse from complete remission after combination chemotherapy. ( Canellos, GP; Chabner, BA; DeVita, VT; Schein, PS; Young, RC, 1975) |
| "45%, respectively, in Hodgkin's disease, and 85% vs." | 1.25 | Combined cyclophosphamide vincristine, procarbazine, and prednisone (COPP) therapy of malignant lymphoma. Evaluation of 190 patients. ( Barros, CA; Morgenfeld, MC; Palau, M; Pavlovsky, A; Pavlovsky, S; Somoza, N; Suarez, A, 1975) |
| "Patients with diffuse histiocytic lymphoma who achieved a complete remission after 6 months of treatment without maintenance have remained disease-free, whereas those with nodular poorly differentiated lymphocytic and diffuse well differentiated lymphocytic lymphomata demonstrate a pattern of continuous late recurrence." | 1.25 | Results of combination chemotherapy of non-Hodgkin's lymphoma. ( Berard, C; Canellos, GP; Chabner, BA; DeVita, VT; Schein, PS; Young, RD, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 53 (60.92) | 18.7374 |
| 1990's | 18 (20.69) | 18.2507 |
| 2000's | 8 (9.20) | 29.6817 |
| 2010's | 8 (9.20) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Okamoto, S | 1 |
| Tanaka, M | 1 |
| Goto, T | 1 |
| Nakashima, M | 1 |
| Nagura, E | 1 |
| Kikukawa, Y | 1 |
| Yamamura-Fujimoto, A | 1 |
| Endo, S | 1 |
| Miyagawa, E | 1 |
| Kawano, Y | 1 |
| Ueno, S | 1 |
| Mitsuya, H | 1 |
| Hata, H | 1 |
| Okuno, Y | 1 |
| Pe'er, J | 1 |
| Rowe, JM | 1 |
| Frenkel, S | 1 |
| Dann, EJ | 1 |
| Miwa, A | 1 |
| Sekiguchi, N | 1 |
| Tanimura, A | 1 |
| Homma, C | 1 |
| Shikai, T | 1 |
| Takezako, Y | 1 |
| Yamagata, N | 1 |
| Takezako, N | 1 |
| Wang, E | 1 |
| Papavassiliou, P | 1 |
| Sebastian, S | 1 |
| Sato, K | 1 |
| Uchiyama, M | 1 |
| Dunleavy, K | 1 |
| Grant, C | 1 |
| Eberle, FC | 1 |
| Pittaluga, S | 1 |
| Jaffe, ES | 1 |
| Wilson, WH | 1 |
| Palickova, M | 1 |
| Mocikova, H | 1 |
| Vernerova, Z | 1 |
| Campr, V | 1 |
| Kozak, T | 1 |
| Hans, CP | 1 |
| Weisenburger, DD | 1 |
| Vose, JM | 1 |
| Hock, LM | 1 |
| Lynch, JC | 1 |
| Aoun, P | 1 |
| Greiner, TC | 1 |
| Chan, WC | 1 |
| Bociek, RG | 1 |
| Bierman, PJ | 1 |
| Armitage, JO | 1 |
| Lee, KW | 1 |
| Kim, DY | 1 |
| Yun, T | 1 |
| Kim, DW | 1 |
| Kim, TY | 1 |
| Yoon, SS | 1 |
| Heo, DS | 1 |
| Bang, YJ | 1 |
| Park, S | 1 |
| Kim, BK | 1 |
| Kim, NK | 1 |
| Arimura, K | 1 |
| Arima, N | 1 |
| Hamada, H | 1 |
| Kukita, T | 1 |
| Matsushita, K | 1 |
| Tei, C | 1 |
| Schneider, T | 1 |
| Tóth, E | 1 |
| Molnár, Z | 1 |
| Várady, E | 1 |
| Deák, B | 1 |
| Horváth, A | 1 |
| Horváth, GI | 1 |
| Eid, H | 1 |
| Schneider, K | 1 |
| Lovey, J | 1 |
| Keresztes, S | 1 |
| Esik, O | 1 |
| Lengyel, Z | 1 |
| Rosta, A | 1 |
| Dem, A | 1 |
| Traore, B | 1 |
| Diallo, BK | 1 |
| Mbodj, M | 1 |
| Dieng, MM | 1 |
| Kasse, AA | 1 |
| Dangou, JM | 1 |
| Diouf, R | 1 |
| Toure, P | 1 |
| Kober, T | 1 |
| Hülsewede, H | 1 |
| Bohlius, J | 1 |
| Engert, A | 1 |
| Carmichael, MG | 1 |
| Portlock, CS | 2 |
| Laurence, J | 1 |
| Coleman, M | 2 |
| Allen, SL | 1 |
| Silver, RT | 1 |
| Pasmantier, M | 1 |
| Schapira, DV | 1 |
| Chudley, AE | 1 |
| Sweet, DL | 1 |
| Golomb, HM | 2 |
| Fisher, RI | 3 |
| DeVita, VT | 10 |
| Bostick, F | 1 |
| Vanhaelen, C | 1 |
| Howser, DM | 1 |
| Hubbard, SM | 1 |
| Young, RC | 8 |
| Matzner, Y | 1 |
| Prococimer, M | 1 |
| Polliack, A | 1 |
| Rubinger, D | 1 |
| Popovtzer, MM | 1 |
| Avilés, A | 1 |
| Díaz-Maqueo, JC | 1 |
| Talavera, A | 1 |
| Nambo, MJ | 1 |
| García, EL | 1 |
| Topilow, AA | 1 |
| Guerra, OR | 1 |
| Tarantolo, SR | 1 |
| Lerner, WA | 1 |
| Snyder, GC | 1 |
| Niitsu, N | 1 |
| Umeda, M | 1 |
| Shirai, T | 1 |
| Brice, P | 1 |
| Pautier, P | 1 |
| Marolleau, JP | 1 |
| Castaigne, S | 1 |
| Gisselbrecht, C | 1 |
| Chamberlain, MC | 1 |
| Dent, S | 1 |
| Eapen, L | 1 |
| Girard, A | 1 |
| Hugenholtz, H | 1 |
| DaSilva, V | 1 |
| Stewart, DJ | 1 |
| Amigo, ML | 1 |
| Revilla, R | 1 |
| Sánchez, C | 1 |
| del Cañizo, C | 1 |
| Caballero, D | 1 |
| San Miguel, JF | 1 |
| Rafi, S | 1 |
| Kaufmann, T | 1 |
| Cesarman, G | 1 |
| Papish, SW | 1 |
| Bernhart, B | 1 |
| Gaynor, M | 1 |
| Reisman, AM | 1 |
| Engelhard, M | 1 |
| Brittinger, G | 1 |
| Huhn, D | 1 |
| Gerhartz, HH | 1 |
| Meusers, P | 1 |
| Siegert, W | 1 |
| Thiel, E | 1 |
| Wilmanns, W | 1 |
| Aydemir, U | 1 |
| Bierwolf, S | 1 |
| Griesser, H | 1 |
| Tiemann, M | 1 |
| Lennert, K | 1 |
| Kaplan, SS | 1 |
| Rybka, WB | 1 |
| Blom, J | 1 |
| Shekhter-Levin, S | 1 |
| Bieri, S | 1 |
| Roggero, E | 1 |
| Zucca, E | 1 |
| Bertoni, F | 1 |
| Pianca, S | 1 |
| Sanna, P | 1 |
| Pedrinis, E | 1 |
| Bernier, J | 1 |
| Cavalli, F | 1 |
| Abrey, LE | 1 |
| Yahalom, J | 1 |
| DeAngelis, LM | 1 |
| Canellos, GP | 7 |
| Chabner, B | 1 |
| Schein, P | 1 |
| Hubbard, SP | 1 |
| Pouillart, P | 1 |
| Hayat, M | 1 |
| Schwarzenberg, L | 1 |
| Amiel, JL | 1 |
| Mathé, G | 1 |
| Tubiana, M | 1 |
| Naysmith, A | 1 |
| Hancock, BW | 1 |
| Cullen, DR | 1 |
| Richmond, J | 1 |
| Wilde, CE | 1 |
| Bennett, JM | 2 |
| Bakemeier, RF | 1 |
| Carbone, PP | 4 |
| Ezdinli, E | 2 |
| Lenhard, RE | 2 |
| Klener, P | 2 |
| Donner, L | 2 |
| Johnson, BL | 1 |
| Simon, R | 1 |
| Anderson, T | 1 |
| Bender, RA | 1 |
| Chabner, BA | 7 |
| Berard, CW | 2 |
| Norton, L | 1 |
| Coltman, CA | 1 |
| Luce, JK | 1 |
| McKelvey, EM | 1 |
| Jones, SE | 1 |
| Moon, TE | 1 |
| Johnson, GJ | 1 |
| Pocock, SJ | 1 |
| Weinerman, BH | 1 |
| Levitt, M | 1 |
| Babick, T | 1 |
| Goldberg, J | 1 |
| Davey, FR | 1 |
| Gottlieb, AJ | 1 |
| Johnson, RE | 1 |
| Brereton, HD | 1 |
| Tigges, FJ | 1 |
| Schmülling, RM | 1 |
| Hiller, E | 1 |
| Waller, HD | 1 |
| Wilms, K | 1 |
| Rubio-Félix, D | 1 |
| Maicas, M | 1 |
| Rubio-Vitaller, A | 1 |
| Gil, JL | 1 |
| Giralt, M | 1 |
| Raichs, A | 1 |
| Harrison, DT | 1 |
| Neiman, PE | 1 |
| Sullivan, K | 1 |
| Hafermann, M | 1 |
| Rudolph, RH | 1 |
| Einstein, AB | 1 |
| Klein, HO | 1 |
| Schein, PS | 3 |
| Morgenfeld, MC | 1 |
| Pavlovsky, A | 1 |
| Suarez, A | 1 |
| Somoza, N | 1 |
| Pavlovsky, S | 1 |
| Palau, M | 1 |
| Barros, CA | 1 |
| Young, RD | 1 |
| Berard, C | 2 |
| Bergsagel, DE | 1 |
| Brown, TC | 1 |
| Reid, J | 1 |
| Durant, JR | 1 |
| Loeb, V | 1 |
| Dorfman, R | 1 |
| Chan, YK | 1 |
| Itoh, T | 1 |
| Sakata, Y | 1 |
| Suzuki, H | 1 |
| Sugimoto, N | 1 |
| Sohma, N | 1 |
| Kishibe, T | 1 |
| Higuchi, S | 1 |
| Seino, Y | 1 |
| Stroup, RM | 1 |
| Sheibani, K | 1 |
| Moncada, A | 1 |
| Purdy, LJ | 1 |
| Battifora, H | 1 |
| O'Reilly, SE | 1 |
| Hoskins, P | 1 |
| Klimo, P | 1 |
| Connors, JM | 1 |
| Munker, R | 1 |
| Nathrath, W | 1 |
| Permanetter, W | 1 |
| Gokel, JM | 1 |
| Debranin, CO | 1 |
| Sivkovich, SA | 1 |
| Kindzel'skiĭ, LP | 1 |
| Galakhin, KA | 1 |
| Todd, MB | 1 |
| Farber, LR | 1 |
| Holford, TR | 1 |
| Bertino, JR | 1 |
| Stewart, FM | 1 |
| Williamson, BR | 1 |
| Innes, DJ | 1 |
| Hess, CE | 1 |
| Jenkin, RD | 1 |
| Anderson, JR | 1 |
| Chilcote, RR | 1 |
| Coccia, P | 1 |
| Exelby, P | 1 |
| Kersey, J | 1 |
| Kjeldsberg, CR | 1 |
| Kushner, J | 1 |
| Meadows, AT | 1 |
| Siegel, S | 1 |
| Hoerni, B | 2 |
| Brunet, R | 1 |
| Hoerni-Simon, G | 2 |
| Hamlin, JA | 1 |
| Kagan, AR | 1 |
| Friedman, NB | 1 |
| Nissen, NI | 1 |
| Walbom-Jorgensen, S | 1 |
| Matsumoto, N | 1 |
| Oyama, H | 1 |
| Matsumura, M | 1 |
| Suetsugu, N | 1 |
| Abe, S | 1 |
| Brodskaia, NA | 1 |
| Rubin, P | 1 |
| Gociu, M | 1 |
| Sherins, RJ | 1 |
| Chauvergne, J | 1 |
| Durand, M | 1 |
| Lagarde, C | 1 |
| De Vita, VT | 1 |
| Schein, PJ | 1 |
| Bagley, CM | 1 |
| Host, H | 1 |
| Abrahamsen, AF | 1 |
| Aungst, CW | 1 |
| Stein, RS | 1 |
| Moran, EM | 1 |
| Desser, RK | 1 |
| Miller, JB | 1 |
| Ultmann, JE | 2 |
| Spivack, SD | 1 |
| Zipp, P | 1 |
| Kountz, SL | 1 |
| Mukherji, B | 1 |
| Oettgen, HF | 1 |
| Yagoda, A | 1 |
| Krakoff, IH | 1 |
| O'Gara, RW | 1 |
| Adamson, RH | 1 |
| Kelly, MG | 1 |
| Dalgard, DW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Dose-Adjusted EPOCH Chemotherapy and Rituximab (CD20+) in Adults and Children With Previously Untreated Patients With Aggressive Non-Hodgkin's Lymphoma[NCT00001337] | Phase 2 | 348 participants (Actual) | Interventional | 1993-05-08 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for procarbazine and Lymphoma, Large B-Cell, Diffuse
| Article | Year |
|---|---|
Gray zone lymphoma: better treated like hodgkin lymphoma or mediastinal large B-cell lymphoma?
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubicin; Hodgkin Disease | 2012 |
Fourth biannual report of the Cochrane Haematological Malignancies Group.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy | 2006 |
Primary mediastinal large B-cell lymphoma: the need for prospective controlled clinical trials.
Topics: Actuarial Analysis; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; | 1999 |
Chemotherapy of non-Hodgkin's lymphomas: Eastern Cooperative Oncology Group experience.
Topics: Altretamine; Bleomycin; Carmustine; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Ad | 1977 |
Non-Hodgkin's lymphoma: recent observations on natural history and intensive treatment.
Topics: Antineoplastic Agents; Burkitt Lymphoma; Cyclophosphamide; Follow-Up Studies; Humans; Lymphoma; Lymp | 1972 |
[Natulan (experimental and clinical data on its antitumor effect)].
Topics: Administration, Oral; Animals; Antineoplastic Agents; Benzoates; Bronchial Neoplasms; Hodgkin Diseas | 1972 |
Management of malignant lymphomas.
Topics: Adrenal Cortex Hormones; Alkylating Agents; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cel | 1973 |
Proceedings: Malignant lymphoma: treatment with combination chemotherapy.
Topics: Adolescent; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Carmustine; Cyclophosphamide; Dru | 1972 |
Drugs 5 years later: procarbazine.
Topics: Animals; Bone Neoplasms; Carcinogens; Carcinoma; Drug Evaluation; Hodgkin Disease; Humans; Lung Neop | 1974 |
14 trials available for procarbazine and Lymphoma, Large B-Cell, Diffuse
| Article | Year |
|---|---|
Ranimustine, ifosfamide, procarbazine, dexamethasone, and etoposide therapy for central nervous system recurrence of diffuse large B-cell lymphoma in patients with poor performance status: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous Syst | 2011 |
Effect of granulocyte colony-stimulating factor in patients with diffuse large cell lymphoma treated with intensive chemotherapy.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Dise | 1994 |
PROMACE-MOPP and intrathecal chemotherapy for CNS lymphomas.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cyclo | 1996 |
CODBLAM IV chemotherapy for large cell lymphoma: sequential use of infusional vincristine and bleomycin and "high dose" consolidation.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dexamethas | 1997 |
Subclassification of diffuse large B-cell lymphomas according to the Kiel classification: distinction of centroblastic and immunoblastic lymphomas is a significant prognostic risk factor.
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Com | 1997 |
Treatment for primary CNS lymphoma: the next step.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous Syst | 2000 |
Clinical trials with BCNU (NSC-409962) in malignant lymphomas by the Eastern Cooperative Oncology Group.
Topics: Bleomycin; Carmustine; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug T | 1976 |
Combination chemotherapy in non-Hodgkin's lymphoma: results of long-term followup.
Topics: Adolescent; Adult; Aged; Bleomycin; Child; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; | 1977 |
Chemotherapy of non-Hodgkin's lymphoma: 10 years' experience in the Southwest Oncology Group.
Topics: Bleomycin; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Administration | 1977 |
Chemotherapy of non-Hodgkin's lymphomas: Eastern Cooperative Oncology Group experience.
Topics: Altretamine; Bleomycin; Carmustine; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Ad | 1977 |
Advanced lymphocytic lymphoma: randomized comparisons of chemotherapy and radiotherapy, alone or in combination.
Topics: Adult; Aged; Blood Platelets; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; | 1977 |
The treatment of diffuse undifferentiated non-Hodgkin's lymphoma in children: the Childrens Cancer Study Group experience.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Clinical | 1985 |
[Chemotherapy of reticulosarcomas. Results of a controlled trial on 60 patients].
Topics: Antineoplastic Agents; Benzoates; Clinical Trials as Topic; Cyclophosphamide; Female; Humans; Lympho | 1973 |
Combination chemotherapy of lymphomas other than Hodgkin's disease.
Topics: Adolescent; Adult; Aged; Bone Marrow; Bone Marrow Cells; Cyclophosphamide; Drug Therapy, Combination | 1974 |
65 other studies available for procarbazine and Lymphoma, Large B-Cell, Diffuse
| Article | Year |
|---|---|
[Clinical Analysis of Combination Chemotherapy Using High Dose Methotrexate, Rituximab, and Vincristine with or without Procarbazine for Elderly Patients with Diffuse Large B-Cell Lymphoma of the Central Nervous System].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neop | 2017 |
Successful Treatment of Bing-Neel Syndrome Accompanying Waldenström's Macroglobulinemia with R-MPV: A Case Report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Female; Humans; Lymphoma, Large B-C | 2015 |
Testicular lymphoma, intraocular (vitreoretinal) lymphoma, and brain lymphoma: involvement of three immunoprivileged sites in one patient.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy | 2010 |
A malignant lymphoma with histological features and immunophenotypic profile intermediate between EBV-positive diffuse large B-cell lymphoma and EBV-positive classical Hodgkin lymphoma in a 67-year-old female: a "gray zone" lymphoma associated with Epstei
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Epst | 2012 |
Isolated central nervous system relapse in a patient with diffuse large B cell lymphoma.
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Central Nerv | 2012 |
BEACOPP escalated and rituximab in the treatment of Hodgkin lymphoma occurring concurrently with diffuse large B-cell non-Hodgkin lymphoma.
Topics: Adult; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bleom | 2013 |
A significant diffuse component predicts for inferior survival in grade 3 follicular lymphoma, but cytologic subtypes do not predict survival.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomyci | 2003 |
Doxorubicin-based chemotherapy for diffuse large B-cell lymphoma in elderly patients: comparison of treatment outcomes between young and elderly patients and the significance of doxorubicin dosage.
Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy P | 2003 |
Cardiac lymphoma successfully treated with high dose chemotherapy followed by autologous haematopoietic stem cell transplantation.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chemotherapy, Adjuvant; Chest Pa | 2003 |
[Treatment of primary mediastinal large B-cell lymphomas].
Topics: Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleo | 2004 |
[Primary lymphoma of the thyroid: a case report].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cyclophosphamide; Hum | 2004 |
Central nervous system anaplastic large cell lymphoma in an adult: successful treatment with a combination of radiation and chemotherapy.
Topics: Adult; Antineoplastic Agents; Central Nervous System Neoplasms; Combined Modality Therapy; Dexametha | 2007 |
Management of the indolent non-Hodgkin's lymphomas.
Topics: Antineoplastic Agents; Bleomycin; Carmustine; Cyclophosphamide; Doxorubicin; Drug Therapy, Combinati | 1980 |
Combination chemotherapy of advanced diffuse histiocytic lymphoma with the six-drug COP-BLAM regimen.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclo | 1982 |
Successful pregnancy following continuous treatment with combination chemotherapy before conception and throughout pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Fema | 1984 |
The treatment of histiocytic lymphoma.
Topics: Antineoplastic Agents; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Leucovorin; Leukopenia; Ly | 1980 |
Persistent immunologic abnormalities in long-term survivors of advanced Hodgkin's disease.
Topics: Adult; Aged; Antineoplastic Agents; Drug Therapy, Combination; Erythrocytes; Hodgkin Disease; Humans | 1980 |
Hypophosphatemia in a patient with lymphoma in leukemic phase.
Topics: Antineoplastic Combined Chemotherapy Protocols; Calcium; Drug Therapy, Combination; Extracellular Sp | 1981 |
COP-BLAM multidrug infusion chemotherapies for lymphoma: results in a community hospital setting.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide | 1993 |
[COP-BLAM III regimen for elderly non-Hodgkin's lymphoma].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubici | 1993 |
Pregnancy after autologous bone marrow transplantation for malignant lymphomas.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclophosphamide; Cyt | 1994 |
Long survival in patients with acquired immune deficiency syndrome-related primary central nervous system lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; C | 1994 |
[Spinal cord compression as the presenting form of non-Hodgkin's lymphoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Doxorub | 1995 |
Tetraploidy in acute myeloid leukemia secondary to large cell lymphoma.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Chromosome Aberra | 1998 |
Advanced diffuse histiocytic lymphoma, a potentially curable disease.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Biopsy; Cyclophosphamide; Drug Therapy, Co | 1975 |
Non-Hodgkin's malignant lymphomata in adults: chemo-radiotherapy in stages III and IV.
Topics: Adult; Antineoplastic Agents; Azirines; Bleomycin; Cyclophosphamide; Daunorubicin; Etoposide; Female | 1975 |
Pituitary function in patients receiving intermittent cytotoxic and corticosteroid therapy for malignant lymphoma.
Topics: Adult; Antineoplastic Agents; Circadian Rhythm; Doxorubicin; Drug Therapy, Combination; Female; Hodg | 1976 |
Imidazole carboxamide (DTIC) in the treatment of advanced lymphomas. Efficacy of DTIC in cases which fail to respond to conventional chemotherupetic combinations.
Topics: Adult; Bleomycin; Cyclophosphamide; Dacarbazine; Drug Evaluation; Drug Resistance; Drug Therapy, Com | 1977 |
Prognostic factors for advanced diffuse histiocytic lymphoma following treatment with combination chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Bone Marrow Diseases; Cyclophosphamide; Doxorubicin; | 1977 |
Diffuse histiocytic lymphoma. The need for aggressive restaging.
Topics: Adult; Aged; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Lymphoma, Large B-Cell, Di | 1977 |
Histiocytic lymphoma of B cell origin.
Topics: B-Lymphocytes; Cell Membrane; Humans; Immunoglobulins; Lymphoma, Large B-Cell, Diffuse; Lymphoma, No | 1977 |
[Polychemotherapy in non-hodgkin lymphoma with a modified MOPP scheme (author's transl)].
Topics: Adult; Cyclophosphamide; Female; Humans; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Dif | 1977 |
[Therapy of non-Hodgkin lymphomas with COP and COPP regimens (author's transl)].
Topics: Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Humans; Lymphoma; Lymphoma, Larg | 1977 |
Combined modality therapy for advanced, diffuse lymphocytic and histiocytic lymphomas.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bone Marrow; Cyclophosphamide; Doxorubicin; Drug The | 1978 |
[Combination chemotherapy and synchronization therapy in lymphogranulomatosis and non-Hodgkin's lymphomas].
Topics: Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Hodgkin Disease; Humans; Lymphom | 1976 |
Non-Hodgkin's lymphoma: patterns of relapse from complete remission after combination chemotherapy.
Topics: Antineoplastic Agents; Bone Marrow; Cyclophosphamide; Drug Therapy, Combination; Humans; Lymph Nodes | 1975 |
Trichlortriethylamine (TS-160 Spofa) in combination chemotherapy of malignant lymphomas.
Topics: Adult; Aged; Antineoplastic Agents; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Lymp | 1975 |
Combined cyclophosphamide vincristine, procarbazine, and prednisone (COPP) therapy of malignant lymphoma. Evaluation of 190 patients.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cyclophosphamide; Drug Therapy, Combination; Femal | 1975 |
Results of combination chemotherapy of non-Hodgkin's lymphoma.
Topics: Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Humans; Lymphoma; Lymphoma, Larg | 1975 |
The influence of chemotherapy on the management of non-Hodgkin's lymphomata at the Princess Margaret Hospital. A comparison of the results from 1962-64 with 1967-69.
Topics: Adult; Aged; Cyclophosphamide; Female; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgki | 1975 |
1,3-bis(2-chloroethyl)-1-nitrosourea(BCNU), cyclophosphamide, vincristine- and prednisone-(BCOP). A new therapeutic regimen for diffuse histiocytic lymphoma.
Topics: Carmustine; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Humans; Lymphoma; Lymphoma, Lar | 1975 |
[A case of diffuse large cell lymphoma treated with combination chemotherapy of CHOP (cyclophosphamide, doxorubicin, vincristine, prednisolone) and BEMP (bleomycin, etoposide, mitoxantrone, procarbazine) with complete remission].
Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophospham | 1992 |
Salvage therapy for diffuse large-cell lymphoma.
Topics: Bleomycin; Cyclophosphamide; Etoposide; Humans; Lymphoma, Large B-Cell, Diffuse; Prednisone; Procarb | 1990 |
Angiotropic (intravascular) large cell lymphoma. A clinicopathologic study of seven cases with unique clinical presentations.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Etop | 1990 |
MACOP-B and VACOP-B in diffuse large cell lymphomas and MOPP/ABV in Hodgkin's disease.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomyc | 1991 |
[Lennert's lymphoma and glomerulonephritis].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Diagnosis, Differential | 1991 |
ECAPP chemotherapy for lymphoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Etoposide; Fema | 1990 |
[The diagnosis and treatment of giant-cell histiocytic non-Hodgkin's lymphoma].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Combined Modality Therapy; Cyclophosp | 1990 |
Prognostic indicators in diffuse large-cell (histiocytic) lymphoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow; Cyclophosphamide; Cytarabine | 1986 |
Residual tumor masses following treatment for advanced histiocytic lymphoma. Diagnostic and therapeutic implications.
Topics: Abdominal Neoplasms; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therap | 1985 |
Treatment of the lymphomas.
Topics: Bleomycin; Burkitt Lymphoma; Drug Synergism; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Ce | 1972 |
[Richter's syndrome. 4 cases and an attempt at analysis].
Topics: Aged; Carcinoma, Squamous Cell; Chlorambucil; Cyclophosphamide; Deglutition Disorders; Drug Therapy, | 1973 |
Lymphomas of the testicle.
Topics: Adult; Aged; Cyclophosphamide; Hodgkin Disease; Humans; Lymph Nodes; Lymphoma; Lymphoma, Large B-Cel | 1972 |
[Hodgkin's disease and other malignant lymphomas].
Topics: Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Prednison | 1972 |
[Treatment of malignant lymphoma with procarbazine].
Topics: Adult; Antineoplastic Agents; Benzoates; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Large B-Cell, | 1972 |
Management of patients with non-Hodgkin's lymphoma.
Topics: Antineoplastic Agents; Burkitt Lymphoma; Cyclophosphamide; Hodgkin Disease; Humans; Lymphography; Ly | 1973 |
Updated Hodgkin's disease. C. Advanced disease and special problems. Comment: the non-Hodgkin's lymphomas.
Topics: Burkitt Lymphoma; Cyclophosphamide; Hodgkin Disease; Humans; Leukemia; Lymphoma; Lymphoma, Large B-C | 1973 |
Effect of drug treatment for lymphoma on male reproductive capacity. Studies of men in remission after therapy.
Topics: Adolescent; Adult; Antineoplastic Agents; Biopsy; Burkitt Lymphoma; Cyclophosphamide; Germ Cells; Ho | 1973 |
Combination chemotherapy with cyclophosphamide, vinblastine, procarbazine and prednisone in the treatment of malignant lymphomas.
Topics: Administration, Oral; Cyclophosphamide; Drug Therapy, Combination; Hodgkin Disease; Humans; Injectio | 1973 |
Potential for prolonged disease-free survival following combination chemotherapy of non-Hodgkin's lymphoma.
Topics: Cyclophosphamide; Drug Therapy, Combination; Humans; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymp | 1974 |
Treatment of Hodgkin's disease and other malignant lymphomas.
Topics: Alkylating Agents; Antineoplastic Agents; Carmustine; Chlorambucil; Cyclohexanes; Cyclophosphamide; | 1973 |
Analysis of the immunosuppressive and oncogenic effects of heterologous antilymphocyte serum.
Topics: Animals; Antilymphocyte Serum; Benzoates; Immunosuppressive Agents; Lymphoma, Large B-Cell, Diffuse; | 1971 |
Cyclic chemotherapy in lymphoma.
Topics: Adult; Aged; Antineoplastic Agents; Benzoates; Cyclophosphamide; Evaluation Studies as Topic; Female | 1971 |
Current concepts in the management of lymphoma.
Topics: Adolescent; Adult; Age Factors; Drug Synergism; Hepatomegaly; Hodgkin Disease; Humans; Immunologic D | 1971 |
Neoplasms of the hematopoietic system in nonhuman primates: report of one spontaneous tumor and two leukemias induced by procarbazine.
Topics: Animals; Antineoplastic Agents; Benzoates; Female; Haplorhini; Hematopoietic System; Leukemia, Exper | 1971 |