procarbazine has been researched along with Lymphoma, AIDS-Related in 13 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Lymphoma, AIDS-Related: B-cell lymphoid tumors that occur in association with AIDS. Patients often present with an advanced stage of disease and highly malignant subtypes including BURKITT LYMPHOMA; IMMUNOBLASTIC LARGE-CELL LYMPHOMA; PRIMARY EFFUSION LYMPHOMA; and DIFFUSE, LARGE B-CELL, LYMPHOMA. The tumors are often disseminated in unusual extranodal sites and chromosomal abnormalities are frequently present. It is likely that polyclonal B-cell lymphoproliferation in AIDS is a complex result of EBV infection, HIV antigenic stimulation, and T-cell-dependent HIV activation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The proportion of intravenous drug abusers (IVDA) in HIV-HD (38%) is higher than in French HIV-infected population as a whole (20." | 3.78 | Human immunodeficiency virus associated Hodgkin's disease: report of 45 cases from the French Registry of HIV-Associated Tumors. ( Andrieu, JM; Brice, P; Colonna, P; Gastaut, JA; Lévy, R; Raphaël, M; Taillan, B; Tourani, JM, 1995) |
| "Hodgkin lymphoma is considered a common type of non-AIDS defining tumor among patients infected with HIV, commonly presenting as a widespread disease and with different pathologic features compared with Hodgkin lymphoma in the general population." | 1.34 | Hodgkin lymphoma among patients infected with HIV in post-HAART era. ( Buccheri, V; Calore, EE; Chamone, DA; Pessoa, VP; Pracchia, LF; Tanaka, PY, 2007) |
| "The occurrence of HIV associated non-Hodgkin's lymphoma (NHL) is a well recognized event." | 1.29 | Hodgkin's disease and non-Hodgkin's lymphoma in an HIV positive patient. ( Brody, J; Goh, JC; Kaplan, MH; Koduru, P; Lichtman, SM; Susin, M, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (53.85) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mwanda, WO | 2 |
| Orem, J | 2 |
| Fu, P | 2 |
| Banura, C | 1 |
| Kakembo, J | 1 |
| Onyango, CA | 1 |
| Ness, A | 2 |
| Reynolds, S | 1 |
| Johnson, JL | 1 |
| Subbiah, V | 1 |
| Bako, J | 1 |
| Wabinga, H | 1 |
| Abdallah, FK | 1 |
| Meyerson, HJ | 1 |
| Whalen, CC | 1 |
| Lederman, MM | 1 |
| Black, J | 1 |
| Ayers, LW | 1 |
| Katongole-Mbidde, E | 1 |
| Remick, SC | 4 |
| Hentrich, M | 1 |
| Berger, M | 1 |
| Wyen, C | 1 |
| Siehl, J | 1 |
| Rockstroh, JK | 1 |
| Müller, M | 1 |
| Fätkenheuer, G | 1 |
| Seidel, E | 1 |
| Nickelsen, M | 1 |
| Wolf, T | 1 |
| Rieke, A | 1 |
| Schürmann, D | 1 |
| Schmidmaier, R | 1 |
| Planker, M | 1 |
| Alt, J | 1 |
| Mosthaf, F | 1 |
| Engert, A | 1 |
| Arasteh, K | 1 |
| Hoffmann, C | 1 |
| Theodossiou, C | 1 |
| Schwarzenberger, P | 1 |
| Tanaka, PY | 1 |
| Pessoa, VP | 1 |
| Pracchia, LF | 1 |
| Buccheri, V | 1 |
| Chamone, DA | 1 |
| Calore, EE | 1 |
| Lévy, R | 1 |
| Colonna, P | 1 |
| Tourani, JM | 1 |
| Gastaut, JA | 1 |
| Brice, P | 1 |
| Raphaël, M | 1 |
| Taillan, B | 1 |
| Andrieu, JM | 1 |
| Tirelli, U | 1 |
| Errante, D | 1 |
| Dolcetti, R | 1 |
| Gloghini, A | 1 |
| Serraino, D | 1 |
| Vaccher, E | 1 |
| Franceschi, S | 1 |
| Boiocchi, M | 1 |
| Carbone, A | 1 |
| Lichtman, SM | 1 |
| Brody, J | 1 |
| Kaplan, MH | 1 |
| Susin, M | 1 |
| Koduru, P | 1 |
| Goh, JC | 1 |
| Chamberlain, MC | 2 |
| McSharry, JJ | 1 |
| Wolf, BC | 1 |
| Blanchard, CG | 2 |
| Eastman, AY | 1 |
| Wagner, H | 1 |
| Portuese, E | 1 |
| Wighton, T | 1 |
| Powell, D | 1 |
| Pearce, T | 1 |
| Brockmeyer, NH | 1 |
| Pohl, G | 1 |
| Mertins, L | 1 |
| Kormanik, PA | 1 |
| Sedransk, N | 1 |
| Haase, RF | 1 |
| Ramnes, CR | 1 |
| Nazeer, T | 1 |
| Mastrianni, DM | 1 |
| Dezube, BJ | 1 |
2 reviews available for procarbazine and Lymphoma, AIDS-Related
| Article | Year |
|---|---|
Non-Hodgkin's lymphomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Humans; Lymphoma, AID | 2002 |
Human immunodeficiency virus associated Hodgkin's disease: report of 45 cases from the French Registry of HIV-Associated Tumors.
Topics: Adult; AIDS-Related Opportunistic Infections; Antineoplastic Combined Chemotherapy Protocols; Bleomy | 1995 |
4 trials available for procarbazine and Lymphoma, AIDS-Related
| Article | Year |
|---|---|
Stage-adapted treatment of HIV-associated Hodgkin lymphoma: results of a prospective multicenter study.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit | 2012 |
Oral combination chemotherapy in the treatment of AIDS-associated Hodgkin's disease.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy | 2005 |
Human immunodeficiency virus associated Hodgkin's disease: report of 45 cases from the French Registry of HIV-Associated Tumors.
Topics: Adult; AIDS-Related Opportunistic Infections; Antineoplastic Combined Chemotherapy Protocols; Bleomy | 1995 |
Oral combination chemotherapy in conjunction with filgrastim (G-CSF) in the treatment of AIDS-related non-Hodgkin's lymphoma: evaluation of the role of G-CSF; quality-of-life analysis and long-term follow-up.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Cyclophosphamide; Etoposide; | 2001 |
8 other studies available for procarbazine and Lymphoma, AIDS-Related
| Article | Year |
|---|---|
Dose-modified oral chemotherapy in the treatment of AIDS-related non-Hodgkin's lymphoma in East Africa.
Topics: Administration, Oral; Adolescent; Adult; Africa South of the Sahara; Antineoplastic Combined Chemoth | 2009 |
Hodgkin lymphoma among patients infected with HIV in post-HAART era.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy, Highly Active; Bleomy | 2007 |
Hodgkin's disease and human immunodeficiency virus infection: clinicopathologic and virologic features of 114 patients from the Italian Cooperative Group on AIDS and Tumors.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antineoplastic Combined Chemotherapy Protocols; Base Sequ | 1995 |
Hodgkin's disease and non-Hodgkin's lymphoma in an HIV positive patient.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Cyclophosphamide; Dexametha | 1993 |
Long survival in patients with acquired immune deficiency syndrome-related primary central nervous system lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; C | 1994 |
Novel oral combination chemotherapy in the treatment of intermediate-grade and high-grade AIDS-related non-Hodgkin's lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Etoposide; Female; Flow Cyt | 1993 |
Combination of chemotherapy and antiviral therapy for Epstein-Barr virus-associated non-Hodgkin's lymphoma of high grade malignancy in cases of HIV infection.
Topics: Acyclovir; Adult; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Bleomycin; Burki | 1997 |
AIDS-related central nervous system lymphomas.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neopl | 1999 |