procarbazine has been researched along with Lung Diseases in 22 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Lung Diseases: Pathological processes involving any part of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gemcitabine was given at a starting dose of 800 mg/m(2) on days 1 and 4 of each cycle." | 2.71 | Severe pulmonary toxicity in patients with advanced-stage Hodgkin's disease treated with a modified bleomycin, doxorubicin, cyclophosphamide, vincristine, procarbazine, prednisone, and gemcitabine (BEACOPP) regimen is probably related to the combination o ( Bredenfeld, H; Diehl, V; Engert, A; Franklin, J; Fries, S; Josting, A; Mailänder, V; Nogova, L; Oertel, J, 2004) |
| " Prospective pharmacokinetic studies to devise a rational dosing strategy for vinblastine in patients receiving ritonavir/lopinavir are warranted." | 1.38 | Incidence, predictors and significance of severe toxicity in patients with human immunodeficiency virus-associated Hodgkin lymphoma. ( Boro, J; Cheung, MC; Ezzat, HM; Harris, M; Hicks, LK; Leitch, HA; Lima, VD; Montaner, JS, 2012) |
| "The majority of patients with Hodgkin's disease can be cured by combination of polychemotherapy and radiotherapy (RT) that can produce late toxic pulmonary and cardiac effects which often remain at a subclinical level." | 1.36 | Cardiopulmonary toxicity of different chemoradiotherapy combined regimens for Hodgkin's disease. ( Bonfante, V; Busia, A; Laffranchi, A; Villani, F; Viviani, S, 2010) |
| "Therefore, 126 patients suffering from Hodgkin's disease were investigated after a follow-up of at least 5 years from the completion of the combined treatment." | 1.35 | Cardiopulmonary response to exercise in patients with different degrees of lung toxicity after radio-chemotherapy for Hodgkin's disease. ( Bonfante, V; Busia, A; Laffranchi, A; Villani, F; Villani, M; Viviani, S, 2009) |
| "Although most patients with Hodgkin's disease refractory to MOPP treatment will respond to either ABVD or B-CAVe chemotherapy, subsequent long-term disease-free survival is unusual." | 1.27 | Combination chemotherapy for advanced Hodgkin's disease after failure of MOPP: ABVD and B-CAVe. ( Harker, WG; Kushlan, P; Rosenberg, SA, 1984) |
| "Procarbazine may have been the responsible agent." | 1.26 | Diffuse pulmonary disease after therapy with nitrogen mustard, vincristine, procarbazine, and prednisone. ( Armstrong, JD; Farney, RJ; Hammer, S; Morris, AH, 1977) |
| "A case of nodular sclerosis Hodgkin's disease, stage IVB, with lung involvement and hypertrophic pulmonary osteoarthropathy (HPOA), was treated with quadruple cytotoxic chemotherapy." | 1.26 | Hypertrophic pulmonary osteoarthropathy in Hodgkin's disease: reversal with chemotherapy. ( Atkinson, MK; McElwain, TJ; Peckham, MJ; Thomas, PP, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (59.09) | 18.7374 |
| 1990's | 4 (18.18) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Villani, F | 4 |
| Busia, A | 2 |
| Villani, M | 1 |
| Laffranchi, A | 2 |
| Viviani, S | 3 |
| Bonfante, V | 3 |
| Ezzat, HM | 1 |
| Cheung, MC | 1 |
| Hicks, LK | 1 |
| Boro, J | 1 |
| Montaner, JS | 1 |
| Lima, VD | 1 |
| Harris, M | 1 |
| Leitch, HA | 1 |
| Bredenfeld, H | 1 |
| Franklin, J | 1 |
| Nogova, L | 1 |
| Josting, A | 1 |
| Fries, S | 1 |
| Mailänder, V | 1 |
| Oertel, J | 1 |
| Diehl, V | 2 |
| Engert, A | 1 |
| Fuchs, M | 1 |
| Harker, WG | 1 |
| Kushlan, P | 1 |
| Rosenberg, SA | 1 |
| Raez, LE | 1 |
| Temple, JD | 1 |
| Saldana, M | 1 |
| Bossi, G | 1 |
| Cerveri, I | 1 |
| Volpini, E | 1 |
| Corsico, A | 1 |
| Baio, A | 1 |
| Corbella, F | 1 |
| Klersy, C | 1 |
| Arico, M | 1 |
| Schein, PS | 1 |
| Winokur, SH | 1 |
| Ecker, MD | 1 |
| Jay, B | 1 |
| Keohane, MF | 1 |
| Sluiter, HJ | 1 |
| Farney, RJ | 1 |
| Morris, AH | 1 |
| Armstrong, JD | 1 |
| Hammer, S | 1 |
| Atkinson, MK | 1 |
| McElwain, TJ | 1 |
| Peckham, MJ | 1 |
| Thomas, PP | 1 |
| Allavena, C | 1 |
| Conroy, T | 1 |
| Aletti, P | 1 |
| Bey, P | 1 |
| Lederlin, P | 1 |
| Shanley, DJ | 1 |
| Lerud, KS | 1 |
| Luetkehans, TJ | 1 |
| Luisetti, M | 1 |
| Peona, V | 1 |
| Salmona, M | 1 |
| Pagnoni, AM | 2 |
| Knerich, R | 1 |
| Genghini, M | 1 |
| Abbà, L | 1 |
| Pozzi, E | 1 |
| Santoro, A | 1 |
| Bonadonna, G | 1 |
| Valagussa, P | 1 |
| Zucali, R | 1 |
| Musumeci, R | 1 |
| Crippa, F | 1 |
| Watchie, J | 1 |
| Coleman, CN | 1 |
| Raffin, TA | 1 |
| Cox, RS | 1 |
| Raubitschek, AA | 1 |
| Fahey, T | 1 |
| Hoppe, RT | 1 |
| Van Kessel, A | 1 |
| Rowland, KM | 1 |
| Murthy, A | 1 |
| Baĭsogolov, GD | 1 |
| Afanasova, NV | 1 |
| Khmelevskaia, ZI | 1 |
| Shakhtarina, SV | 1 |
| Dohner, VA | 1 |
| Ward, HP | 1 |
| Standord, RE | 1 |
| Jones, SE | 1 |
| Moore, M | 1 |
| Blank, N | 1 |
| Castellino, RA | 1 |
3 reviews available for procarbazine and Lung Diseases
| Article | Year |
|---|---|
Will BEACOPP be the standard for high risk Hodgkin lymphoma patients in advanced stages?
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Cyclophosphamid | 2007 |
Immunosuppressive and cytotoxic chemotherapy: long-term complications.
Topics: Alkylating Agents; Antineoplastic Agents; Azathioprine; Bleomycin; Busulfan; Carcinogens; Chemical a | 1975 |
Hodgkin's disease: long-term effects of therapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Brain; Female; Genitalia, Fem | 1986 |
2 trials available for procarbazine and Lung Diseases
| Article | Year |
|---|---|
Severe pulmonary toxicity in patients with advanced-stage Hodgkin's disease treated with a modified bleomycin, doxorubicin, cyclophosphamide, vincristine, procarbazine, prednisone, and gemcitabine (BEACOPP) regimen is probably related to the combination o
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide | 2004 |
Long-term results of combined chemotherapy-radiotherapy approach in Hodgkin's disease: superiority of ABVD plus radiotherapy versus MOPP plus radiotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Topic; Combined | 1987 |
17 other studies available for procarbazine and Lung Diseases
| Article | Year |
|---|---|
Cardiopulmonary response to exercise in patients with different degrees of lung toxicity after radio-chemotherapy for Hodgkin's disease.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cardiovascular Diseases; Com | 2009 |
Cardiopulmonary toxicity of different chemoradiotherapy combined regimens for Hodgkin's disease.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cardiovascular Diseases; Com | 2010 |
Incidence, predictors and significance of severe toxicity in patients with human immunodeficiency virus-associated Hodgkin lymphoma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy, Highly Active; Bleomy | 2012 |
Combination chemotherapy for advanced Hodgkin's disease after failure of MOPP: ABVD and B-CAVe.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit | 1984 |
Successful treatment of lymphomatoid granulomatosis using cyclosporin-A after failure of intensive chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; CD4-Positive T-Lymphocytes; Combined Modality Therap | 1996 |
Long-term pulmonary sequelae after treatment of childhood Hodgkin's disease.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Child, Preschool; Comb | 1997 |
Procarbazine lung.
Topics: Humans; Lung Diseases; Male; Middle Aged; Pleural Effusion; Procarbazine; Radiography | 1978 |
[Learning by doing].
Topics: Adult; Beclomethasone; Bis-Trimethylammonium Compounds; Bronchial Neoplasms; Carcinoma, Small Cell; | 1977 |
Diffuse pulmonary disease after therapy with nitrogen mustard, vincristine, procarbazine, and prednisone.
Topics: Adult; Biopsy; Drug Hypersensitivity; Female; Hodgkin Disease; Humans; Lung Diseases; Mechlorethamin | 1977 |
Hypertrophic pulmonary osteoarthropathy in Hodgkin's disease: reversal with chemotherapy.
Topics: Adult; Antineoplastic Agents; Drug Therapy, Combination; Hodgkin Disease; Humans; Lung Diseases; Mal | 1976 |
Late cardiopulmonary toxicity after treatment for Hodgkin's disease.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Exerci | 1992 |
Development of pulmonary histiocytosis X after chemotherapy for Hodgkin disease.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubicin; Fem | 1990 |
Ambroxol and pulmonary toxicity induced by antineoplastic drugs.
Topics: Ambroxol; Animals; Antineoplastic Agents; Bleomycin; Bromhexine; Busulfan; Cyclophosphamide; Humans; | 1986 |
Minimal long-term cardiopulmonary dysfunction following treatment for Hodgkin's disease.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Body Composition; Elec | 1987 |
[Changes in the lungs in patients with lymphogranulomatosis, Stages I-II, following combination therapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; | 1985 |
Alveolitis during procarbazine, vincristine and cyclophosphamide therapy.
Topics: Antineoplastic Agents; Cyclophosphamide; Humans; Lung; Lung Diseases; Lymphoma, Non-Hodgkin; Male; M | 1972 |
Hypersensitivity to procarbazine (Matulane) manifested by fever and pleuropulmonary reaction.
Topics: Administration, Oral; Antineoplastic Agents; Benzoates; Diagnosis, Differential; Drug Combinations; | 1972 |