Page last updated: 2024-11-03

procarbazine and Leukopenia

procarbazine has been researched along with Leukopenia in 42 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Leukopenia: A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000).

Research Excerpts

ExcerptRelevanceReference
"We undertook a phase II study of combination chemotherapy with mechlorethamine (nitrogen mustard) 6 mg/m2 intravenously day 1 and day 8, vincristine 2 mg intravenously day 1 and day 8, and procarbazine 100 mg/m2 orally days 1 through 14 (MOP) in adults with recurrent high-grade glioma."9.06Mechlorethamine, vincristine, and procarbazine chemotherapy for recurrent high-grade glioma in adults: a phase II study. ( Baptista, J; Clark, K; Coyle, T; Graziano, S; King, R; Kirshner, J; Newman-Palmer, N; Poiesz, B; Scalzo, A; Winfield, J, 1990)
"Thirty patients with disseminated cutaneous malignant melanoma were treated with a three-drug cytotoxic chemotherapy program consisting of CCNU, procarbazine, and vincristine."7.66Combination cytotoxic chemotherapy with CCNU, procarbazine, and vincristine in disseminated cutaneous malignant melanoma: 3 years, followup. ( Carmo-Pereira, J; Costa, FO; Henriques, E; Pimentel, P, 1980)
"We undertook a phase II study of combination chemotherapy with mechlorethamine (nitrogen mustard) 6 mg/m2 intravenously day 1 and day 8, vincristine 2 mg intravenously day 1 and day 8, and procarbazine 100 mg/m2 orally days 1 through 14 (MOP) in adults with recurrent high-grade glioma."5.06Mechlorethamine, vincristine, and procarbazine chemotherapy for recurrent high-grade glioma in adults: a phase II study. ( Baptista, J; Clark, K; Coyle, T; Graziano, S; King, R; Kirshner, J; Newman-Palmer, N; Poiesz, B; Scalzo, A; Winfield, J, 1990)
"Twelve patients with relapsed or refractory malignant lymphoma were treated with IMV-triple P regimen consisting of ifosfamide (IFM), mitoxantrone (MIT), vindesine (VDS), pepleomycin (PEP), procarbazine (PCZ) and prednisolone (PDN)."3.68[Salvage chemotherapy with IMV-triple P for relapsed or refractory malignant lymphoma]. ( Arai, N; Hara, A; Shirai, T; Umeda, M, 1991)
"Thirty patients with disseminated cutaneous malignant melanoma were treated with a three-drug cytotoxic chemotherapy program consisting of CCNU, procarbazine, and vincristine."3.66Combination cytotoxic chemotherapy with CCNU, procarbazine, and vincristine in disseminated cutaneous malignant melanoma: 3 years, followup. ( Carmo-Pereira, J; Costa, FO; Henriques, E; Pimentel, P, 1980)
"To improve survival of elderly patients with primary central nervous system lymphoma (PCNSL), we conducted a phase II study with high-dose methotrexate (MTX) combined with procarbazine and CCNU."2.74High-dose methotrexate combined with procarbazine and CCNU for primary CNS lymphoma in the elderly: results of a prospective pilot and phase II study. ( Deckert, M; Feuerhake, F; Finke, J; Ihorst, G; Illerhaus, G; Marks, R; Müller, F; Ostertag, C, 2009)
" Despite increased hematotoxicity, moderate dose escalation is safe for the majority of the patients with G-CSF assistance and standard supportive treatment."2.69Acute hematologic toxicity and practicability of dose-intensified BEACOPP chemotherapy for advanced stage Hodgkin's disease. German Hodgkin's Lymphoma Study Group (GHSG). ( Diehl, V; Engel, C; Loeffler, M; Schmitz, S; Tesch, H, 2000)
"However, leukocytopenia was observed in many patients despite combined use of G-CSF, suggesting the dose and administration method of THP should be studied further."2.68[Usefulness of THP-COPBLM therapy in elderly patients with non-Hodgkin's lymphoma]. ( Nakayama, M; Niitsu, N; Umeda, M, 1997)
"Thirty-four children with Hodgkin's disease were treated during the years 1969--75."2.64MVPP chemotherapy combined with radiotherapy in the treatment of Hodgkin's disease in children. ( Armata, J; Borkowski, W; Depowska, T; Depowski, M; Kaczor, Z; Stopyrowa, J; Strzeszynski, J, 1978)
"Although G-CSF is widely used to prevent or ameliorate leukopenia during cytotoxic chemotherapies, its optimal use is still under debate and depends on many therapy parameters such as dosing and timing of cytotoxic drugs and G-CSF, G-CSF pharmaceuticals used and individual risk factors of patients."1.48Model-based optimization of G-CSF treatment during cytotoxic chemotherapy. ( Engel, C; Loeffler, M; Loibl, S; Schirm, S; Scholz, M, 2018)
"Of 6 patients who developed recurrence, 3 (7."1.33[Comparison of preliminary results of involved-field with extended field radiotherapy combined with chemotherapy for early stage Hodgkin's disease]. ( Han, JZ; Jin, J; Li, YX; Liu, XF; Liu, YP; Song, YW; Wang, SL; Wang, WH; Yu, ZH; Zhou, LQ, 2006)
" The optimal dosing for MV26PD remains to be determined."1.27Treatment of refractory lymphoma with methotrexate, VM-26 (teniposide), procarbazine, and dexamethasone: Cancer and Leukemia Group B study 7902. ( Anderson, J; Bloomfield, CD; Cooper, MR; Ginsberg, SJ; Gottlieb, AJ; Hurd, DD; Lachant, NA, 1988)
"One patient with Hodgkin's disease involving the liver is alive at 36 months with further therapy."1.26Adriamycin, bleomycin, DIC, CCNU, and prednisone (ABDIC) chemotherapy in MOPP-resistant Hodgkin's disease. ( Gamble, JF; Loh, KK; Rodgers, RW; Shullenberger, CC, 1980)
"Thirty-eight patients with advanced Hodgkin's disease were treated with a combination of cyclophosphamide, vinblastine, procarbazine, and prednisone (CVPP)."1.26Combinaed chemotherapy with cyclophosphamide, vinblastine, procarbazine, and prednisone (CVPP) for patients with advanced Hodgkin's disease. An alternative program to MOPP. ( Bloomfield, CD; Fortuny, I; Kennedy, BJ; Vosika, G; Weiss, RB, 1976)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199027 (64.29)18.7374
1990's7 (16.67)18.2507
2000's7 (16.67)29.6817
2010's1 (2.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schirm, S1
Engel, C2
Loibl, S1
Loeffler, M2
Scholz, M1
Illerhaus, G1
Marks, R1
Müller, F1
Ihorst, G1
Feuerhake, F1
Deckert, M1
Ostertag, C1
Finke, J1
Niu, Y1
Shi, YK1
He, XH1
Feng, FY1
Zhou, LQ2
Gu, DZ1
Zander, T1
Nettekoven, W1
Kraus, JA1
Pels, H1
Ko, YD1
Vetter, H1
Klockgether, T1
Schlegel, U1
Sieber, M1
Bredenfeld, H1
Josting, A1
Reineke, T1
Rueffer, U1
Koch, T1
Naumann, R1
Boissevain, F1
Koch, P1
Worst, P1
Soekler, M1
Eich, H1
Müller-Hermelink, HK1
Franklin, J1
Paulus, U1
Wolf, J1
Engert, A1
Diehl, V2
Yamanaka, R1
Morii, K1
Shinbo, Y1
Takeuchi, S1
Tamura, T1
Hondoh, H1
Takahashi, H2
Onda, K1
Tanaka, R1
Wang, WH1
Li, YX1
Song, YW1
Jin, J1
Liu, YP1
Wang, SL1
Liu, XF1
Yu, ZH1
Han, JZ1
Rodgers, RW1
Gamble, JF2
Loh, KK1
Shullenberger, CC2
Aisner, J1
Whitacre, M1
Van Echo, DA1
Wiernik, PH1
Armata, J2
Cyklis, R1
Grześkowiak-Melanowska, J1
Fisher, RI1
DeVita, VT1
Hubbard, SM1
Longo, DL1
Wesley, R1
Chabner, BA1
Young, RC1
Wagener, DJ1
Burgers, JM1
Dekker, AW1
Kazem, I1
van Peperzeel, HA1
Qasim, MM1
Sizoo, W1
Somers, R1
Kroese, WF1
Sweet, DL1
Golomb, HM1
Carmo-Pereira, J1
Costa, FO1
Pimentel, P1
Henriques, E1
Canellos, GP1
Petroni, GR1
Barcos, M1
Duggan, DB1
Peterson, BA1
Niitsu, N2
Hara, A3
Umeda, M4
Shirai, T3
Nakayama, M1
Dunlop, DJ1
Eatock, MM1
Paul, J1
Anderson, S1
Reed, NS1
Soukop, M1
Lucie, N1
Fitzsimmons, EJ1
Tansey, P1
Steward, WP1
Schmitz, S1
Tesch, H1
Hansen, HH1
Selawry, OS1
Simon, R1
Carr, DT1
van Wyk, CE1
Tucker, RD1
Sealy, R1
Stopyrowa, J1
Depowski, M1
Strzeszynski, J1
Borkowski, W1
Kaczor, Z1
Depowska, T1
Hartwich, G1
Neidhardt, B1
Bloomfield, CD2
Weiss, RB1
Fortuny, I1
Vosika, G1
Kennedy, BJ1
de Kreek, EJ1
Sybesma, HB1
Arai, N2
Coyle, T1
Baptista, J1
Winfield, J1
Clark, K1
Poiesz, B1
Kirshner, J1
Scalzo, A1
Newman-Palmer, N1
King, R1
Graziano, S1
Lachant, NA1
Anderson, J1
Ginsberg, SJ1
Cooper, MR1
Hurd, DD1
Gottlieb, AJ1
Abate, G1
Comella, P1
Di Pietro, N1
Ganzina, F1
Pergola, M1
Silvestro, P1
Basso, A1
Salvatore, M1
Zarrilli, D1
Lehnert, M1
Biffl, G1
Wascher, H1
Jordis-Lohausen, K1
Wählby, S1
Ezdinli, EZ1
Anderson, JR1
Melvin, F1
Glick, JH1
Davis, TE1
O'Connell, MJ1
Mechl, Z1
Krejcí, P1
Dold, U1
Desser, RK1
Ultmann, JE1
Stenzel, L1
Krug, K1
Schingnitz, G1
Sacks, P1
Jacobs, P1
Gale, D1
Lynch, SR1
Bothwell, TH1
Stevens, K1
Vasantha Kumar, AR1
Renaudin, J1
Wilson, CB1
Boldrey, EB1
Enot, KJ1
Levin, VA1
Host, H1
Abrahamsen, AF1
Mubashir, BA1
Fairley, GH1
Mukherji, B1
Oettgen, HF1
Yagoda, A1
Krakoff, IH1
Floersheim, GL1
Brune, K1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of Patients Over 65 Years With Primary CNS Lymphoma: High-dose Methotrexate Combined With Chemo-immunotherapy Followed by Maintenance Therapy[NCT00989352]Phase 256 participants (Anticipated)Interventional2009-09-30Recruiting
A Prospective, Open, Randomized Controlled, Multi-center Phase III Clinical Trial Comparing High-dose Epirubicin and Standard-dose Epirubicin in R±CEOP in Newly Diagnosed Young Patients With Medium/High-risk Diffuse Large B-cell Lymphoma[NCT03151044]Phase 3408 participants (Anticipated)Interventional2016-07-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for procarbazine and Leukopenia

ArticleYear
[Chemotherapy of malignant lymphomas].
    Fortschritte der Medizin, 1978, Jun-08, Volume: 96, Issue:22

    Topics: Cyclophosphamide; Drug Therapy, Combination; Hodgkin Disease; Humans; Leukopenia; Lymphoma; Neoplasm

1978
The sensitivity of Hodgkin's disease to chemotherapeutic agents administered singly.
    Series haematologica (1968), 1973, Volume: 6, Issue:2

    Topics: Adrenal Cortex Hormones; Alopecia; Antineoplastic Agents; Bleomycin; Blood Platelet Disorders; Carmu

1973

Trials

11 trials available for procarbazine and Leukopenia

ArticleYear
High-dose methotrexate combined with procarbazine and CCNU for primary CNS lymphoma in the elderly: results of a prospective pilot and phase II study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20, Issue:2

    Topics: Aged; Anemia; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Comb

2009
14-day variant of the bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone regimen in advanced-stage Hodgkin's lymphoma: results of a pilot study of the German Hodgkin's Lymphoma Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, May-01, Volume: 21, Issue:9

    Topics: Adolescent; Adult; Anemia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphami

2003
Combination chemotherapy for small cell carcinoma of the lung: continuous versus alternating non-cross-resistant combinations.
    Cancer treatment reports, 1982, Volume: 66, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Small Cell; Cyclophosphamide; Doxoru

1982
Etoposide, vinblastine, and doxorubicin: an active regimen for the treatment of Hodgkin's disease in relapse following MOPP. Cancer and Leukemia Group B.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Disease-Free Survival; Doxorubici

1995
[Usefulness of THP-COPBLM therapy in elderly patients with non-Hodgkin's lymphoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:1

    Topics: Aged; Aged, 80 and over; Anemia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclopho

1997
Randomized multicentre trial of filgrastim as an adjunct to combination chemotherapy for Hodgkin's disease. West of Scotland Lymphoma Group.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1998, Volume: 10, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chemotherapy,

1998
Acute hematologic toxicity and practicability of dose-intensified BEACOPP chemotherapy for advanced stage Hodgkin's disease. German Hodgkin's Lymphoma Study Group (GHSG).
    Annals of oncology : official journal of the European Society for Medical Oncology, 2000, Volume: 11, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Blood Platelets;

2000
Combination chemotherapy of advanced lung cancer: a randomized trial.
    Cancer, 1976, Volume: 38, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Bronchogenic; Carcinoma, Small Cell;

1976
MVPP chemotherapy combined with radiotherapy in the treatment of Hodgkin's disease in children.
    Acta paediatrica Scandinavica, 1978, Volume: 67, Issue:3

    Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Clinical Trials as Topic; Drug Evaluatio

1978
Mechlorethamine, vincristine, and procarbazine chemotherapy for recurrent high-grade glioma in adults: a phase II study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; G

1990
Moderate versus aggressive chemotherapy of nodular lymphocytic poorly differentiated lymphoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclophosphamide; Female; Follow-Up Stud

1985

Other Studies

29 other studies available for procarbazine and Leukopenia

ArticleYear
Model-based optimization of G-CSF treatment during cytotoxic chemotherapy.
    Journal of cancer research and clinical oncology, 2018, Volume: 144, Issue:2

    Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxo

2018
[Combined-modality therapy for 150 cases of early-stage Hodgkin's lymphoma].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2008, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child;

2008
Intensified PCV-chemotherapy with optional stem cell support in recurrent malignant oligodendroglioma.
    Journal of neurology, 2002, Volume: 249, Issue:8

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Brain Neoplasms; Female

2002
Modified ProMACE-MOPP hybrid regimen with moderate-dose methotrexate for patients with primary CNS lymphoma.
    Annals of hematology, 2005, Volume: 84, Issue:7

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Centra

2005
[Comparison of preliminary results of involved-field with extended field radiotherapy combined with chemotherapy for early stage Hodgkin's disease].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2006, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit

2006
Adriamycin, bleomycin, DIC, CCNU, and prednisone (ABDIC) chemotherapy in MOPP-resistant Hodgkin's disease.
    Cancer, 1980, Dec-01, Volume: 46, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bleomycin; Dacarbazine; Doxorubicin; Drug Administra

1980
[Effect of splenectomy on the leukocyte count during the treatment of children with Hodgkin's disease].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1984, Sep-01, Volume: 37, Issue:17

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Hodgkin Disease

1984
Diffuse aggressive lymphomas: increased survival after alternating flexible sequences of proMACE and MOPP chemotherapy.
    Annals of internal medicine, 1983, Volume: 98, Issue:3

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bloo

1983
Sequential non-cross-resistant chemotherapy regimens (MOPP and CAVmP) in Hodgkin's disease stage IIIB and IV.
    Cancer, 1983, Nov-01, Volume: 52, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy;

1983
The treatment of histiocytic lymphoma.
    Seminars in oncology, 1980, Volume: 7, Issue:3

    Topics: Antineoplastic Agents; Cyclophosphamide; Cytarabine; Doxorubicin; Humans; Leucovorin; Leukopenia; Ly

1980
Combination cytotoxic chemotherapy with CCNU, procarbazine, and vincristine in disseminated cutaneous malignant melanoma: 3 years, followup.
    Cancer treatment reports, 1980, Volume: 64, Issue:1

    Topics: Adult; Aged; Female; Follow-Up Studies; Humans; Leukopenia; Lomustine; Male; Melanoma; Middle Aged;

1980
[Treatment with ACVP-16 for relapsed and refractory non-Hodgkin's lymphoma].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1993, Volume: 34, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carboplat

1993
Combinaed chemotherapy with cyclophosphamide, vinblastine, procarbazine, and prednisone (CVPP) for patients with advanced Hodgkin's disease. An alternative program to MOPP.
    Cancer, 1976, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Age Factors; Aged; Alopecia; Antineoplastic Agents; Cyclophosphamide; Drug Therap

1976
[From tumors to scales].
    Nederlands tijdschrift voor geneeskunde, 1975, Jul-26, Volume: 119, Issue:30

    Topics: Agranulocytosis; Humans; Immunologic Deficiency Syndromes; Leg Ulcer; Leukopenia; Male; Mechloretham

1975
[The COP-BLAM therapy for malignant lymphoma].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1990, Volume: 31, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophos

1990
[Salvage chemotherapy with IMV-triple P for relapsed or refractory malignant lymphoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Drug Evaluation; Female; Hea

1991
Treatment of refractory lymphoma with methotrexate, VM-26 (teniposide), procarbazine, and dexamethasone: Cancer and Leukemia Group B study 7902.
    Medical and pediatric oncology, 1988, Volume: 16, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Dexametha

1988
Epirubicin in combination chemotherapy in the treatment of advanced stage non-Hodgkin's lymphomas.
    Tumori, 1987, Feb-28, Volume: 73, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathies; Cyclophosphamide; Doxorubic

1987
A preliminary analysis of combination therapy with vincristine, adriamycin, and prednimustine (VAP) in advanced breast cancer: a phase II study.
    Seminars in oncology, 1986, Volume: 13, Issue:1 Suppl 1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dac

1986
Procarbazin in advanced malignant melanoma.
    Neoplasma, 1986, Volume: 33, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Female; Humans; Leukopenia; M

1986
[Cytostatic therapy of bronchial carcinoma].
    Deutsche medizinische Wochenschrift (1946), 1972, Apr-14, Volume: 97, Issue:15

    Topics: Antineoplastic Agents; Bronchial Neoplasms; Cyclophosphamide; Humans; Leukopenia; Methotrexate; Pall

1972
[Results of polychemotherapy in neoplasms of the lymphoreticular system].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1973, May-01, Volume: 28, Issue:9

    Topics: Antineoplastic Agents; Cyclophosphamide; Hodgkin Disease; Humans; Infections; Leukopenia; Long-Term

1973
Combination chemotherapy in the treatment of advanced Hodgkin's disease.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Jun-02, Volume: 47, Issue:21

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Benzoates; Female; Hodgkin Disease; Humans; Leukopen

1973
Procarbazine hydrochloride in the treatment of brain tumors. Phase 2 study.
    Journal of neurosurgery, 1974, Volume: 40, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Astrocytoma; Brain Neoplasms; Child; Electroencephalography; Epe

1974
Combination chemotherapy with cyclophosphamide, vinblastine, procarbazine and prednisone in the treatment of malignant lymphomas.
    Scandinavian journal of haematology, 1973, Volume: 10, Issue:3

    Topics: Administration, Oral; Cyclophosphamide; Drug Therapy, Combination; Hodgkin Disease; Humans; Injectio

1973
Treatment of advanced Hodgkin's disease with combination chemotherapy.
    Southern medical journal, 1973, Volume: 66, Issue:7

    Topics: Adult; Antineoplastic Agents; Dactinomycin; Drug Therapy, Combination; Female; Hodgkin Disease; Huma

1973
The use of different drugs and combinations in the treatment of Hodgkin's disease.
    Series haematologica (1968), 1973, Volume: 6, Issue:2

    Topics: Administration, Oral; Anemia; Drug Evaluation; Drug Therapy, Combination; Hodgkin Disease; Humans; I

1973
Cyclic chemotherapy in lymphoma.
    Cancer, 1971, Volume: 28, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Benzoates; Cyclophosphamide; Evaluation Studies as Topic; Female

1971
The haematological response to the immunosuppressive methylhydrazine derivates procarbazine and Ro 4-6824.
    Acta haematologica, 1971, Volume: 46, Issue:2

    Topics: Animals; Antilymphocyte Serum; Antineoplastic Agents; Benzoates; Blood Platelets; Body Weight; Eryth

1971