procarbazine has been researched along with Leukoencephalopathy, Progressive Multifocal in 2 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Leukoencephalopathy, Progressive Multifocal: An opportunistic viral infection of the central nervous system associated with conditions that impair cell-mediated immunity (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME and other IMMUNOLOGIC DEFICIENCY SYNDROMES; HEMATOLOGIC NEOPLASMS; IMMUNOSUPPRESSION; and COLLAGEN DISEASES). The causative organism is JC Polyomavirus (JC VIRUS) which primarily affects oligodendrocytes, resulting in multiple areas of demyelination. Clinical manifestations include DEMENTIA; ATAXIA; visual disturbances; and other focal neurologic deficits, generally progressing to a vegetative state within 6 months. (From Joynt, Clinical Neurology, 1996, Ch26, pp36-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intracraneal manifestations of Hodgkin's Disease (HD) are extremely rare, with an estimated incidence rate of approximately 0." | 1.33 | [Limphomatous meningitis as recurrence site in Hodgkin's disease]. ( Corrado, C; Greco, M; Niccodemi, C; Presas, J; Valsecchi, M; Winkel, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Greco, M | 1 |
| Valsecchi, M | 1 |
| Niccodemi, C | 1 |
| Presas, J | 1 |
| Corrado, C | 1 |
| Winkel, M | 1 |
| Grundstein-Amado, R | 1 |
2 other studies available for procarbazine and Leukoencephalopathy, Progressive Multifocal
| Article | Year |
|---|---|
[Limphomatous meningitis as recurrence site in Hodgkin's disease].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Bleomycin; Cisplatin; Cycloph | 2006 |
Ethical decision-making processes used by health care providers.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Decision Making; Decision Theory; Ethical Ana | 1993 |