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procarbazine and Leukemia, Myelomonocytic, Acute

procarbazine has been researched along with Leukemia, Myelomonocytic, Acute in 1 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Leukemia, Myelomonocytic, Acute: A pediatric acute myeloid leukemia involving both myeloid and monocytoid precursors. At least 20% of non-erythroid cells are of monocytic origin.

Research Excerpts

ExcerptRelevanceReference
"Between 1978 and 1988, 20 children with medulloblastoma (MB) of the brain were treated postoperatively with MOPP (nitrogen mustard, vincristine, prednisone, and procarbazine)."3.68Therapy-related myelodysplastic syndrome in children with medulloblastoma following MOPP chemotherapy. ( Hayani, A; Mahoney, DH; Taylor, LD, 1992)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hayani, A1
Mahoney, DH1
Taylor, LD1

Other Studies

1 other study available for procarbazine and Leukemia, Myelomonocytic, Acute

ArticleYear
Therapy-related myelodysplastic syndrome in children with medulloblastoma following MOPP chemotherapy.
    Journal of neuro-oncology, 1992, Volume: 14, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Preschool

1992