procarbazine has been researched along with Leukemia, Myeloid in 16 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Leukemia, Myeloid: Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report two patients with acute myeloid leukemia (AML) following therapy for malignant glioma; one was a young women treated heavily with alkylating agents for glioblastoma and the other a young man treated with high doses of procarbazine, lomustine, and vincristine (PCV) for anaplastic astrocytoma." | 4.80 | Acute leukemia following treatment of malignant glioma. ( Brown, MT; Gockerman, JP; Perry, JR, 1998) |
| "Hodgkin's disease is curable in the majority of patients, although a proportion of patients are resistant to or relapse after initial therapy." | 1.30 | High-dose BEAM chemotherapy with autologous haemopoietic stem cell transplantation for Hodgkin's disease is unlikely to be associated with a major increased risk of secondary MDS/AML. ( Devereux, S; Goldstone, AH; Gregory, W; Hancock, B; Harrison, CN; Hoskin, P; Hudson, GV; Linch, DC; MacMillan, AK; Milligan, D; Newland, AC; Winfield, D, 1999) |
| "Nine patients with aplastic anemia rejected their first graft." | 1.26 | Experience with second marrow transplants. ( Buckner, CD; Clift, RA; Fefer, A; Neiman, PE; Storb, R; Thomas, ED; Wright, SE, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (50.00) | 18.7374 |
| 1990's | 7 (43.75) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Metayer, C | 1 |
| Curtis, RE | 1 |
| Vose, J | 1 |
| Sobocinski, KA | 1 |
| Horowitz, MM | 1 |
| Bhatia, S | 1 |
| Fay, JW | 1 |
| Freytes, CO | 1 |
| Goldstein, SC | 1 |
| Herzig, RH | 1 |
| Keating, A | 1 |
| Miller, CB | 1 |
| Nevill, TJ | 1 |
| Pecora, AL | 1 |
| Rizzo, JD | 1 |
| Williams, SF | 1 |
| Li, CY | 1 |
| Travis, LB | 1 |
| Weisdorf, DJ | 1 |
| Lira, P | 1 |
| Grebe, G | 1 |
| Tsodikov, A | 1 |
| Loeffler, M | 1 |
| Yakovlev, A | 1 |
| Perry, JR | 1 |
| Brown, MT | 1 |
| Gockerman, JP | 1 |
| Kaplan, SS | 1 |
| Rybka, WB | 1 |
| Blom, J | 1 |
| Shekhter-Levin, S | 1 |
| Osaka, M | 1 |
| Rowley, JD | 1 |
| Zeleznik-Le, NJ | 1 |
| Harrison, CN | 1 |
| Gregory, W | 1 |
| Hudson, GV | 1 |
| Devereux, S | 1 |
| Goldstone, AH | 1 |
| Hancock, B | 1 |
| Winfield, D | 1 |
| MacMillan, AK | 1 |
| Hoskin, P | 1 |
| Newland, AC | 1 |
| Milligan, D | 1 |
| Linch, DC | 1 |
| Wright, SE | 1 |
| Thomas, ED | 1 |
| Buckner, CD | 1 |
| Clift, RA | 1 |
| Fefer, A | 1 |
| Neiman, PE | 1 |
| Storb, R | 1 |
| Stutzman, L | 1 |
| Strauss, B | 1 |
| Sagher, D | 1 |
| Karrison, T | 1 |
| Schwartz, J | 1 |
| Larson, R | 1 |
| Williams, S | 1 |
| Selby, P | 1 |
| Patel, P | 1 |
| Milan, S | 1 |
| Meldrum, M | 1 |
| Mansi, J | 1 |
| Mbidde, E | 1 |
| Brada, M | 1 |
| Perren, T | 1 |
| Forgeson, G | 1 |
| Gore, M | 1 |
| Cuzick, J | 1 |
| Kobayashi, T | 1 |
| Dunkel, VC | 1 |
| Myers, SL | 1 |
| Rodriguez, V | 1 |
| Bodey, GP | 1 |
| Freireich, EJ | 1 |
| O'Gara, RW | 1 |
| Adamson, RH | 1 |
| Kelly, MG | 1 |
| Dalgard, DW | 1 |
3 reviews available for procarbazine and Leukemia, Myeloid
| Article | Year |
|---|---|
Acute leukemia following treatment of malignant glioma.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Fatal Outcome | 1998 |
Current status of treatment of lymphomas.
Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Drug Therapy, Combin | 1975 |
Combination chemotherapy for lymphomas and leukemias.
Topics: Adult; Burkitt Lymphoma; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Combinations; Hodgk | 1973 |
13 other studies available for procarbazine and Leukemia, Myeloid
| Article | Year |
|---|---|
Myelodysplastic syndrome and acute myeloid leukemia after autotransplantation for lymphoma: a multicenter case-control study.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemoth | 2003 |
[Acute non-lymphatic leukemia after treatment of Hodgkin's lymphoma with chemotherapy and radiotherapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cytarabine; Dacarbazine; Daunorubi | 1984 |
A cure model with time-changing risk factor: an application to the analysis of secondary leukaemia. A report from the International Database on Hodgkin's Disease.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Disease-Fr | 1998 |
Tetraploidy in acute myeloid leukemia secondary to large cell lymphoma.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Chromosome Aberra | 1998 |
MSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25).
Topics: Acute Disease; Amino Acid Sequence; Animals; Antineoplastic Combined Chemotherapy Protocols; Base Se | 1999 |
High-dose BEAM chemotherapy with autologous haemopoietic stem cell transplantation for Hodgkin's disease is unlikely to be associated with a major increased risk of secondary MDS/AML.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; | 1999 |
Experience with second marrow transplants.
Topics: Anemia, Aplastic; Bone Marrow Cells; Bone Marrow Transplantation; Cyclophosphamide; Graft Rejection; | 1976 |
Methyl transferase activity in secondary leukemia.
Topics: Acute Disease; B-Lymphocytes; Cell Line; Cell Transformation, Viral; DNA Repair; Herpesvirus 4, Huma | 1990 |
ChlVPP combination chemotherapy for Hodgkin's disease: long-term results.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Mar | 1990 |
A method for analysing case-control studies with ordinal exposure variables.
Topics: Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Biometry; Burkitt Lymphoma; Cl | 1985 |
[New developments in chemotherapy for experimental brain metastasis].
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Daunorubicin; Doxorubicin; Flo | 1985 |
Continuous lymphoblastoid cell line from a rhesus monkey with myelogenous leukemia.
Topics: Animals; Cell Line; Cells, Cultured; Fluorescent Antibody Technique; Haplorhini; Herpesvirus 4, Huma | 1972 |
Neoplasms of the hematopoietic system in nonhuman primates: report of one spontaneous tumor and two leukemias induced by procarbazine.
Topics: Animals; Antineoplastic Agents; Benzoates; Female; Haplorhini; Hematopoietic System; Leukemia, Exper | 1971 |