Page last updated: 2024-11-03

procarbazine and Leukemia, Myelogenous, Chronic, BCR-ABL Positive

procarbazine has been researched along with Leukemia, Myelogenous, Chronic, BCR-ABL Positive in 4 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Leukemia, Myelogenous, Chronic, BCR-ABL Positive: Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rancea, M1
Will, A1
Borchmann, P1
Monsef, I1
Engert, A1
Skoetz, N1
Sharkunov, NN1
Moiseyeva, TN1
Zybunova, EE1
Vinogradova, OY1
Kravchenko, SK1
Au, WY1
Ma, SK1
Wan, TS1
Wang, EP1
Lau, TC1
Kwong, YL1
Avilés, A1
Díaz-Maqueo, JC1
Talavera, A1
Guzmán, R1
García, EL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Maternal Cancer Diagnosis and Treatment During Pregnancy:a Registry for Maternal, Fetal, and Neonatal Outcomes With Longitudinal Follow up of Child Development and Maternal Psychological Well Being[NCT02749474]400 participants (Anticipated)Observational [Patient Registry]2003-07-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for procarbazine and Leukemia, Myelogenous, Chronic, BCR-ABL Positive

ArticleYear
Fifteenth biannual report of the Cochrane Haematological Malignancies Group--focus on non-Hodgkin's lymphoma.
    Journal of the National Cancer Institute, 2013, Aug-07, Volume: 105, Issue:15

    Topics: Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols;

2013
[Successful treatment for Hodgkin's lymphoma in a female patient with Ph+ chronic myeloid leukemia].
    Terapevticheskii arkhiv, 2012, Volume: 84, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bleomycin; Cyclophosphamide; Doxo

2012
Concurrent mediastinal B cell lymphoma and chronic myeloid leukemia with an unusually favorable response to chemotherapy.
    Leukemia & lymphoma, 2003, Volume: 44, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Clone Cells; Combined Modal

2003
Growth and development of children of mothers treated with chemotherapy during pregnancy: current status of 43 children.
    American journal of hematology, 1991, Volume: 36, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Behavior; Bleomyci

1991