procarbazine has been researched along with Leucocythaemia in 65 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the last two decades, it has become evident that secondary leukemias after Hodgkin's disease (HD) are mainly caused by the treatment with alkylating agents, especially mechlorethamine." | 9.08 | Low risk of secondary leukemias after chemotherapy without mechlorethamine in childhood Hodgkin's disease. German-Austrian Pediatric Hodgkin's Disease Group. ( Creutzig, U; Gadner, H; Harbott, J; Mann, G; Riepenhausen, M; Ritter, J; Schellong, G, 1997) |
| "In the last two decades, it has become evident that secondary leukemias after Hodgkin's disease (HD) are mainly caused by the treatment with alkylating agents, especially mechlorethamine." | 5.08 | Low risk of secondary leukemias after chemotherapy without mechlorethamine in childhood Hodgkin's disease. German-Austrian Pediatric Hodgkin's Disease Group. ( Creutzig, U; Gadner, H; Harbott, J; Mann, G; Riepenhausen, M; Ritter, J; Schellong, G, 1997) |
| " Patients were randomized in the Southwest Oncology Group (later the Pediatric Oncology Group [POG] to involved-field (IF) radiotherapy alone or IF radiotherapy followed by six courses of mechlorethamine, vincristine, prednisone, and procarbazine (MOPP) chemotherapy; patients in the Children's Cancer Study Group (CCSG) and Cancer and Leukemia Group B (CALGB) were randomized to receive extended-field (EF) radiotherapy or IF radiotherapy followed by six courses of MOPP." | 5.06 | The intergroup Hodgkin's disease in children. A study of stages I and II. ( Fryer, C; Fuller, LM; Gehan, EA; Gilchrist, GS; Hanson, W; Hays, DM; Heller, R; Johnston, J; Kennedy, P; Sullivan, MP, 1990) |
| " protocol consisting of: vincristine-prednisone plus surgery and/or radiotherapy as induction treatment, craniocervical radiotherapy and intrathecal methotrexate as CNS preventive treatment and anti-leukemia (6-mercaptopurine, methotrexate and vincristine-prednisone pulses) or anti-lymphoma (COPP) treatment as maintenance, in a randomized trial." | 5.04 | Non-Hodgkin's lymphoma in children: an analysis of 122 cases from Argentina. ( Cebrian-Bonesana, A; Kvicala, R; Lein, JM; Ojeda, FG; Pavlovsky, S; Penchansky, L; Pependieck, C; Roca-Garcia, C; Sackmann-Muriel, S; Schvartzman, E, 1978) |
| " After a median follow-up of more than 6 years following MOPP (mechlorethamine/vincristine/procarbazine/prednisone) chemotherapy with or without radiotherapy, 5% of patients with Hodgkin's disease developed second primaries, 60% of which were leukemias." | 4.78 | Cytotoxic chemotherapy-induced second primary neoplasms: clinical aspects. ( Petru, E; Schmähl, D, 1991) |
| " The risk of treatment-induced acute leukemias as well as sterility can be avoided or greatly decreased with drug combinations not including procarbazine HCI and alkylating agents." | 4.77 | Chemotherapy of malignant lymphomas. ( Bonadonna, G, 1985) |
| "Most patients with early-stage Hodgkin's disease can now be cured by one of several therapeutic approaches." | 2.37 | Early-stage Hodgkin's disease: current approaches to treatment. ( MacKenzie, R; Rusthoven, JJ, 1985) |
| "The prognosis of patients with Hodgkin's disease has dramatically improved over the past few decades." | 2.37 | Current management of Hodgkin's disease. ( Behrens, BC; DeVita, VT; Young, RC, 1985) |
| "Concerning ANLL, the MOPP regimen was significantly associated with a higher risk: 3." | 1.31 | Fifteen-year secondary leukaemia risk observed in 761 patients with Hodgkin's disease prospectively treated by MOPP or ABVD chemotherapy plus high-dose irradiation. ( Andrieu, JM; Colonna, P; Delwail, V; Jais, JP, 2002) |
| "Risk of leukemia was 0." | 1.30 | The risk of acute leukemia in patients treated for Hodgkin's disease is significantly higher aft [see bined modality programs than after chemotherapy alone and is correlated with the extent of radiotherapy and type and duration of chemotherapy: a case-con ( Anselmo, AP; Baroni, CD; Bernasconi, C; Brusamolino, E; Klersy, C; Lazzarino, M; Lunghi, F; Mandelli, F; Maurizi-Enrici, R; Orlandi, E; Pagnucco, G; Santoro, M, 1998) |
| " All other disease stages will require a different strategy that should consist of radiotherapy combined with short-term effective regimens, such as ABVD (doxorubicin, bleomycin, vinblastine and decarbazine) or VBM (vinblastine, bleomycin and methotrexate) to reduce the incidence of MOPP-associated gonadal dysfunction and leukaemogenesis." | 1.28 | Early stage Hodgkin's disease: ten-year results of a non-randomised study with radiotherapy alone or combined with MOPP. ( Banfi, A; Bonadonna, G; Bonfante, V; Devizzi, L; Santoro, A; Tesoro Tess, JD; Valagussa, P; Viviani, S; Zanini, M; Zucali, R, 1992) |
| "Thirty-four subsequent second malignant neoplasms were observed in 33 patients among those treated for Hodgkin's disease." | 1.27 | Second malignant neoplasms complicating Hodgkin's disease: the National Cancer Institute experience. ( DeVita, VT; Glatstein, E; Kelley, PA; Kinsella, TJ; Makuch, RW; Tester, WJ; Waller, B, 1984) |
| "Patients who had a relapse of Hodgkin's disease did not have an increased incidence of second malignancy." | 1.27 | Second malignancy complicating Hodgkin's disease. ( Mercier, JP; Tawil, E, 1983) |
| "Secondary acute leukemias are rare in the evolution of malignant gliomas and the usefulness of subsequent radiochemotherapy cannot be questioned at the present time." | 1.27 | Two cases of acute leukemia following treatment of malignant glioma. ( Audebert, AA; Canuel, C; Debray, J; Genot, JY; Krulik, M; Poisson, M; Renoux, M; Smadja, N; van Efferterre, R, 1983) |
| "Diagnosis and therapy of malignant lymphoma of the skin were reviewed." | 1.27 | [Malignant lymphoma of the skin]. ( Miyamoto, H; Nakajima, H, 1985) |
| " Since the absorption rate is not clinically relevant in patients on long-term glycoside therapy, our results indicate that digitoxin is preferable to digoxin in such patients." | 1.26 | Cytostatic drugs are without significant effect on digitoxin plasma level and renal excretion. ( Kuhlmann, J; Rietbrock, N; Wilke, J, 1982) |
| "Stage II Hodgkin's disease probably should be divided into two substages requiring different treatment." | 1.26 | [The current state of curability of Hodgkin's disease]. ( Streuli, RA; Ultmann, JE, 1981) |
| "Nine patients with aplastic anemia rejected their first graft." | 1.26 | Experience with second marrow transplants. ( Buckner, CD; Clift, RA; Fefer, A; Neiman, PE; Storb, R; Thomas, ED; Wright, SE, 1976) |
| "We studied 680 patients with Hodgkin's disease, treated at Stanford University Medical Center from July 1, 1968, through December 31, 1975, to determine the risk of development of hematologic neoplasia." | 1.26 | Hematologic neoplasia in patients treated for Hodgkin's disease. ( Coleman, CN; Flint, A; Glatstein, EJ; Kaplan, HS; Rosenberg, SA; Williams, CJ, 1977) |
| "Azathioprine was best tolerated, but gave only medium results whereas procarbazine, as a very potent drug, had the highest rate of side effects (especially depression of bone marrow, infections, gastrointestinal manifestations etc." | 1.25 | [Side effects in immunosuppressive therapy]. ( Thumb, N, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 50 (76.92) | 18.7374 |
| 1990's | 11 (16.92) | 18.2507 |
| 2000's | 4 (6.15) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diehl, V | 2 |
| Franklin, J | 2 |
| Pfreundschuh, M | 2 |
| Lathan, B | 2 |
| Paulus, U | 1 |
| Hasenclever, D | 2 |
| Tesch, H | 2 |
| Herrmann, R | 1 |
| Dörken, B | 1 |
| Müller-Hermelink, HK | 1 |
| Dühmke, E | 1 |
| Loeffler, M | 2 |
| BEGEMANN, H | 1 |
| BLUM, KU | 1 |
| FELLMER, KE | 1 |
| FOELSCH, E | 1 |
| GERHARTZ, H | 1 |
| GRUNZE, H | 1 |
| HAUSMANN, K | 2 |
| HENNES, R | 1 |
| JUENGLING, W | 1 |
| KLEIBEL, F | 1 |
| KOERTGE, P | 1 |
| MARING, H | 1 |
| MARTIN, H | 1 |
| OBRECHT, P | 1 |
| OSTEN, W | 1 |
| PABST, HW | 1 |
| POLIWODA, H | 1 |
| SCHUBERT, JC | 1 |
| SEIDL, S | 1 |
| SPECHTER, HJ | 1 |
| STRICKSTROCK, KH | 1 |
| WITTE, S | 1 |
| DREWS, J | 1 |
| Valagussa, P | 2 |
| Santoro, A | 3 |
| Fossati Bellani, F | 1 |
| Franchi, F | 1 |
| Banfi, A | 2 |
| Bonadonna, G | 4 |
| Freireich, EJ | 1 |
| Keating, M | 1 |
| Cabanillas, F | 1 |
| Barlogie, B | 1 |
| Canellos, GP | 1 |
| Vorob'ev, AI | 1 |
| Brilliant, MD | 1 |
| Voltarelli, JC | 1 |
| Falcão, RP | 1 |
| Bottura, C | 1 |
| Tester, WJ | 1 |
| Kinsella, TJ | 1 |
| Waller, B | 1 |
| Makuch, RW | 1 |
| Kelley, PA | 1 |
| Glatstein, E | 2 |
| DeVita, VT | 5 |
| Jacquillat, C | 1 |
| Auclerc, G | 1 |
| Weil, M | 1 |
| Auclerc, MF | 1 |
| Maral, J | 1 |
| Tawil, E | 1 |
| Mercier, JP | 1 |
| Aisenberg, AC | 1 |
| Adamson, RH | 1 |
| Seiber, SM | 1 |
| Genot, JY | 1 |
| Krulik, M | 1 |
| Poisson, M | 1 |
| van Efferterre, R | 1 |
| Renoux, M | 1 |
| Audebert, AA | 1 |
| Canuel, C | 1 |
| Smadja, N | 1 |
| Debray, J | 1 |
| Gassmann, W | 1 |
| Schmitz, N | 2 |
| Löffler, H | 2 |
| Kuhlmann, J | 1 |
| Wilke, J | 1 |
| Rietbrock, N | 1 |
| Pflieger, H | 1 |
| Wiesneth, M | 1 |
| Arnold, R | 1 |
| Niethammer, D | 1 |
| Kleihauer, E | 1 |
| Streuli, RA | 1 |
| Ultmann, JE | 1 |
| Zdziarska, B | 1 |
| Nowacki, P | 1 |
| Millo, B | 1 |
| Schellong, G | 1 |
| Riepenhausen, M | 1 |
| Creutzig, U | 1 |
| Ritter, J | 1 |
| Harbott, J | 1 |
| Mann, G | 1 |
| Gadner, H | 1 |
| Brusamolino, E | 1 |
| Anselmo, AP | 1 |
| Klersy, C | 1 |
| Santoro, M | 1 |
| Orlandi, E | 1 |
| Pagnucco, G | 1 |
| Lunghi, F | 1 |
| Maurizi-Enrici, R | 1 |
| Baroni, CD | 1 |
| Lazzarino, M | 1 |
| Mandelli, F | 1 |
| Bernasconi, C | 1 |
| Sieber, M | 1 |
| Rüffer, U | 1 |
| Engert, A | 1 |
| Schalk, KP | 1 |
| Schwieder, G | 1 |
| Wulf, G | 1 |
| Dölken, G | 1 |
| Worst, P | 1 |
| Koch, P | 1 |
| Bruntsch, U | 1 |
| Tirier, C | 1 |
| Müller, U | 1 |
| Cellai, E | 1 |
| Magrini, SM | 1 |
| Masala, G | 1 |
| Alterini, R | 1 |
| Costantini, AS | 1 |
| Rigacci, L | 1 |
| Olmastroni, L | 1 |
| Papi, MG | 1 |
| Spediacci, MA | 1 |
| Innocenti, F | 1 |
| Bellesi, G | 1 |
| Ferrini, PR | 1 |
| Biti, G | 1 |
| Avilés, A | 3 |
| Neri, N | 1 |
| Delwail, V | 1 |
| Jais, JP | 1 |
| Colonna, P | 1 |
| Andrieu, JM | 1 |
| Garrett, MJ | 1 |
| Das, S | 1 |
| Smith, JD | 1 |
| Freedman, LS | 1 |
| Klimek, A | 1 |
| Krykowski, E | 1 |
| Poźiak-Patewicz, E | 1 |
| Carl, W | 1 |
| Nissen, NI | 1 |
| Pajak, TF | 1 |
| Glidewell, O | 1 |
| Pedersen-Bjergaard, J | 1 |
| Stutzman, L | 1 |
| Falkson, G | 1 |
| Cuttner, J | 1 |
| Blom, J | 1 |
| Leone, L | 1 |
| Sawitsky, A | 1 |
| Coleman, M | 1 |
| Haurani, F | 1 |
| Spurr, CL | 1 |
| Harley, JB | 1 |
| Seligman, B | 1 |
| Cornell, C | 1 |
| Henry, P | 1 |
| Senn, HJ | 1 |
| Brunner, K | 1 |
| Martz, G | 1 |
| Maurice, P | 1 |
| Bank, A | 1 |
| Shapiro, L | 1 |
| James, GW | 1 |
| Holland, JF | 1 |
| Santos, GW | 1 |
| Elfenbein, GJ | 1 |
| Tutschka, PJ | 1 |
| Cebrian-Bonesana, A | 1 |
| Schvartzman, E | 1 |
| Roca-Garcia, C | 1 |
| Pependieck, C | 1 |
| Sackmann-Muriel, S | 1 |
| Ojeda, FG | 1 |
| Kvicala, R | 1 |
| Pavlovsky, S | 1 |
| Lein, JM | 1 |
| Penchansky, L | 1 |
| Wright, SE | 1 |
| Thomas, ED | 1 |
| Buckner, CD | 1 |
| Clift, RA | 1 |
| Fefer, A | 1 |
| Neiman, PE | 1 |
| Storb, R | 1 |
| Coleman, CN | 1 |
| Williams, CJ | 1 |
| Flint, A | 1 |
| Glatstein, EJ | 1 |
| Rosenberg, SA | 1 |
| Kaplan, HS | 1 |
| Yoshikawa, H | 1 |
| Takeyama, H | 1 |
| Ishiguro, J | 1 |
| Yamada, K | 1 |
| Suenaga, M | 1 |
| Thumb, N | 1 |
| Díaz-Maqueo, JC | 2 |
| Ayala, JR | 1 |
| Cortés, HD | 1 |
| García, EL | 2 |
| Bonfante, V | 1 |
| Viviani, S | 1 |
| Zucali, R | 1 |
| Devizzi, L | 1 |
| Zanini, M | 1 |
| Tesoro Tess, JD | 1 |
| Talavera, A | 1 |
| Guzmán, R | 1 |
| Longo, DL | 3 |
| Duffey, PL | 2 |
| Wiernik, PH | 1 |
| Hubbard, SM | 2 |
| Phares, JC | 1 |
| Bastian, AW | 1 |
| Jaffe, ES | 2 |
| Young, RC | 4 |
| Zurborn, KH | 1 |
| Gram, J | 1 |
| Glander, K | 1 |
| Delbrück, K | 1 |
| Pelzer, H | 1 |
| Bruhn, HD | 1 |
| Petru, E | 1 |
| Schmähl, D | 1 |
| Gehan, EA | 1 |
| Sullivan, MP | 1 |
| Fuller, LM | 1 |
| Johnston, J | 1 |
| Kennedy, P | 1 |
| Fryer, C | 1 |
| Gilchrist, GS | 1 |
| Hays, DM | 1 |
| Hanson, W | 1 |
| Heller, R | 1 |
| Lowenthal, RM | 1 |
| Jestrimski, KW | 1 |
| Sagher, D | 1 |
| Karrison, T | 1 |
| Schwartz, JL | 1 |
| Larson, R | 1 |
| Meier, P | 1 |
| Strauss, B | 1 |
| Ihde, DC | 1 |
| Straus, DJ | 1 |
| Maekawa, I | 1 |
| Kawamura, T | 1 |
| Miyake, T | 1 |
| Boccaccio, P | 1 |
| Rosa, F | 1 |
| Casciaro, S | 1 |
| D'Elia, P | 1 |
| Romagnoli, M | 1 |
| Ghio, R | 1 |
| España, P | 1 |
| Bonilla, F | 1 |
| Yebra, M | 1 |
| Diego, J | 1 |
| Alvarez de Mon, M | 1 |
| Marazuela, M | 1 |
| Durántez, A | 1 |
| Rowland, KM | 1 |
| Murthy, A | 1 |
| Sizoo, W | 1 |
| Hagenbeek, A | 1 |
| Löwenberg, B | 1 |
| Blayney, DW | 1 |
| Greene, MH | 1 |
| Postal, MG | 1 |
| Nakajima, H | 1 |
| Miyamoto, H | 1 |
| Rusthoven, JJ | 1 |
| MacKenzie, R | 1 |
| Virgolini, L | 1 |
| Behrens, BC | 1 |
| Carbone, PP | 1 |
| Fleischer, J | 1 |
| Hartwich, G | 1 |
| Rubin, P | 1 |
| Frei, E | 1 |
| Brunning, RD | 1 |
| Düllmann, J | 1 |
| Wulfhekel, U | 1 |
| Drescher, S | 1 |
| Morrone, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Maternal Cancer Diagnosis and Treatment During Pregnancy:a Registry for Maternal, Fetal, and Neonatal Outcomes With Longitudinal Follow up of Child Development and Maternal Psychological Well Being[NCT02749474] | 400 participants (Anticipated) | Observational [Patient Registry] | 2003-07-31 | Recruiting | |||
| A Phase II Trial of Combined Weekly Bortezomib and Tositumomab I-131 in Patients With Relapsed or Refractory Follicular Non-Hodg[NCT00479167] | Phase 2 | 1 participants (Actual) | Interventional | 2007-05-31 | Terminated (stopped due to Lack of accrual and interest in study) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
13 reviews available for procarbazine and Leucocythaemia
| Article | Year |
|---|---|
ABVD chemotherapy in the treatment of Hodgkin's disease.
Topics: Antineoplastic Agents; Bleomycin; Clinical Trials as Topic; Dacarbazine; Doxorubicin; Drug Resistanc | 1982 |
The hematologic malignancies. Leukemia, lymphoma, and myeloma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cyclophosphamide; Doxor | 1984 |
Chemically induced leukemia in humans.
Topics: Benzene; Chlorambucil; Chloramphenicol; Cyclophosphamide; Humans; Leukemia; Melphalan; Phenylbutazon | 1981 |
Bone marrow transplantation--present status.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow; Bone Marrow Transplantation; Cyclophosphamide; | 1979 |
Cytotoxic chemotherapy-induced second primary neoplasms: clinical aspects.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Hod | 1991 |
Corticosteroid drugs: their role in oncological practice.
Topics: Adrenal Cortex Hormones; Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Breast | 1986 |
Chemotherapy of malignant lymphomas.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubicin; Drug Resistance | 1985 |
Treatment of advanced Hodgkin's disease.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Top | 1989 |
Hodgkin's disease: long-term effects of therapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Brain; Female; Genitalia, Fem | 1986 |
Early-stage Hodgkin's disease: current approaches to treatment.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Fem | 1985 |
[Neutrophil leukemia. Review of the literature].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Examination; Busulfan; Fema | 1985 |
Current management of Hodgkin's disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Hodgkin Disease; Humans; | 1985 |
[Cytostatic chemotherapy of neoplasms in children].
Topics: Adrenal Cortex Hormones; Aminopterin; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; | 1971 |
10 trials available for procarbazine and Leucocythaemia
| Article | Year |
|---|---|
Standard and increased-dose BEACOPP chemotherapy compared with COPP-ABVD for advanced Hodgkin's disease.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cyclopho | 2003 |
ABVD chemotherapy in the treatment of Hodgkin's disease.
Topics: Antineoplastic Agents; Bleomycin; Clinical Trials as Topic; Dacarbazine; Doxorubicin; Drug Resistanc | 1982 |
Low risk of secondary leukemias after chemotherapy without mechlorethamine in childhood Hodgkin's disease. German-Austrian Pediatric Hodgkin's Disease Group.
Topics: Adolescent; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Child | 1997 |
Moderate dose escalation for advanced stage Hodgkin's disease using the bleomycin, etoposide, adriamycin, cyclophosphamide, vincristine, procarbazine, and prednisone scheme and adjuvant radiotherapy: a study of the German Hodgkin's Lymphoma Study Group.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dose | 1998 |
A comparative study of a BCNU containing 4-drug program versus MOPP versus 3-drug combinations in advanced Hodgkin's disease: a cooperative study by the Cancer and Leukemia Group B.
Topics: Adult; Antineoplastic Agents; Carmustine; Clinical Trials as Topic; Drug Therapy, Combination; Femal | 1979 |
Non-Hodgkin's lymphoma in children: an analysis of 122 cases from Argentina.
Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Cyclophosphamide; Drug Therapy, Combinat | 1978 |
Treatment of advanced-stage Hodgkin's disease: alternating noncrossresistant MOPP/CABS is not superior to MOPP.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dose-Re | 1991 |
The intergroup Hodgkin's disease in children. A study of stages I and II.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Hodgki | 1990 |
The treatment of indolent lymphomas: watchful waiting v aggressive combined modality treatment.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Doxorub | 1988 |
Treatment of advanced Hodgkin's disease.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials as Top | 1989 |
44 other studies available for procarbazine and Leucocythaemia
| Article | Year |
|---|---|
[RESULTS OF CLINICAL TESTS OF A NEW CYTOSTATIC SUBSTANCE FROM THE METHYLHYDRAZINE SERIES (NATULAN)].
Topics: Antineoplastic Agents; Drug Therapy; Hodgkin Disease; Humans; Hydrazines; Leukemia; Leukemia, Lympho | 1965 |
Absence of treatment-induced second neoplasms after ABVD in Hodgkin's disease.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Aged; Bleomycin; Child; Child, Preschool; Daca | 1982 |
Therapy-related leukemia: a necessary complication of successful systemic chemotherapy?
Topics: Alkylating Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Hodgkin Di | 1984 |
[Various disputable problems of ambulatory treatment of tumors of the blood system].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophosphamide; Doxorubicin; Hodgkin | 1984 |
Antibody-dependent cellular cytotoxicity in some lymphoreticular diseases.
Topics: Antibody-Dependent Cell Cytotoxicity; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphami | 1984 |
Second malignant neoplasms complicating Hodgkin's disease: the National Cancer Institute experience.
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Combine | 1984 |
[Acute leukemias and solid tumors in the course of Hodgkin disease].
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoco | 1983 |
Second malignancy complicating Hodgkin's disease.
Topics: Acute Disease; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cycloph | 1983 |
Acute nonlymphocytic leukemia after treatment for Hodgkin's disease.
Topics: Acute Disease; Adult; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy | 1983 |
Two cases of acute leukemia following treatment of malignant glioma.
Topics: Acute Disease; Adult; Astrocytoma; Brain Neoplasms; Female; Glioma; Humans; Leukemia; Nitrosourea Co | 1983 |
[10 years of DeVita protocol].
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Therapy, Combination; Hodgkin Disease; Humans; | 1982 |
Cytostatic drugs are without significant effect on digitoxin plasma level and renal excretion.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabin | 1982 |
Granulocyte transfusions in children.
Topics: Acute Disease; Agranulocytosis; Anemia, Aplastic; Antilymphocyte Serum; Blood Transfusion; Bone Marr | 1981 |
[The current state of curability of Hodgkin's disease].
Topics: Chromosome Aberrations; Drug Therapy, Combination; Hodgkin Disease; Humans; Leukemia; Mechlorethamin | 1981 |
[Dysfunction of the blood-brain barrier in patients with acute leukemias or lymphomas of high grade malignancy].
Topics: Adolescent; Adult; Aged; Albumins; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Blood- | 1995 |
The risk of acute leukemia in patients treated for Hodgkin's disease is significantly higher aft [see bined modality programs than after chemotherapy alone and is correlated with the extent of radiotherapy and type and duration of chemotherapy: a case-con
Topics: Abdomen; Actuarial Analysis; Acute Disease; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; | 1998 |
The risk of second malignant tumors and its consequences for the overall survival of Hodgkin's disease patients and for the choice of their treatment at presentation: analysis of a series of 1524 cases consecutively treated at the Florence University Hosp
Topics: Adult; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Confidence Intervals; F | 2001 |
Hematological malignancies and pregnancy: a final report of 84 children who received chemotherapy in utero.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Behavior; Bleomyci | 2001 |
Fifteen-year secondary leukaemia risk observed in 761 patients with Hodgkin's disease prospectively treated by MOPP or ABVD chemotherapy plus high-dose irradiation.
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbaz | 2002 |
Long term experience with combination chemotherapy in advanced Hodgkin's disease.
Topics: Adult; Antineoplastic Agents; Bleomycin; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; | 1977 |
[Polyneuropathy in patients with Hodgkin's disease and acute leukemia treated by the combined cyclic method according to the MOPP and POMP schedules].
Topics: Adult; Aged; Antineoplastic Agents; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Leuk | 1976 |
Cancer chemotherapy and dentistry.
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Asparaginase; Carci | 1977 |
Experience with second marrow transplants.
Topics: Anemia, Aplastic; Bone Marrow Cells; Bone Marrow Transplantation; Cyclophosphamide; Graft Rejection; | 1976 |
Hematologic neoplasia in patients treated for Hodgkin's disease.
Topics: Adult; Child; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Leukemia; Male; Mechloreth | 1977 |
[A case of "chronic" leukemic reticuloendotheliosis with excellent response to chemotherapy (author's transl)].
Topics: Adult; Betamethasone; Chronic Disease; Cyclophosphamide; Drug Therapy, Combination; Humans; Leukemia | 1975 |
[Side effects in immunosuppressive therapy].
Topics: Alopecia; Amenorrhea; Anemia; Azathioprine; Bacterial Infections; Chlorambucil; Female; Humans; Immu | 1975 |
Hodgkin's disease and acute leukemia. Is it a true association?
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil | 1992 |
Early stage Hodgkin's disease: ten-year results of a non-randomised study with radiotherapy alone or combined with MOPP.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; | 1992 |
Growth and development of children of mothers treated with chemotherapy during pregnancy: current status of 43 children.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Behavior; Bleomyci | 1991 |
Influence of cytostatic treatment on the coagulation system and fibrinolysis in patients with non-Hodgkin's lymphomas and acute leukemias.
Topics: Acute Disease; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antithrombin I | 1991 |
Low O6-alkylguanine DNA alkyltransferase activity in the peripheral blood lymphocytes of patients with therapy-related acute nonlymphocytic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubicin; Hodgkin Disease | 1988 |
[Adult T-cell leukemia and non-Hodgkin's lymphoma in brothers].
Topics: Antibodies, Viral; Antineoplastic Combined Chemotherapy Protocols; Deltaretrovirus Antibodies; Doxor | 1986 |
[Acute leukemia in patients treated for Hodgkin's disease].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Hodgkin Disease; Human | 1988 |
[Second tumors in patients treated for Hodgkin's disease].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modali | 1988 |
[Myelodysplastic syndromes: a group of preleukemic disorders].
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Leukemia | 1987 |
Decreasing risk of leukemia with prolonged follow-up after chemotherapy and radiotherapy for Hodgkin's disease.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Combined Modality Therapy; | 1987 |
[Malignant lymphoma of the skin].
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Diagnos | 1985 |
International Symposium on Hodgkin's Disease. Session 4. Small group workshops. Report on workshop: Chemotherapy.
Topics: Antineoplastic Agents; Bleomycin; Carmustine; Doxorubicin; Drug Therapy, Combination; Hodgkin Diseas | 1973 |
[Standarization of therapy in hemaoblastoses and malignant lymphomas as shown on the sample of lymphogranulomatosis].
Topics: Acute Disease; Cyclophosphamide; Hodgkin Disease; Humans; Leukemia; Long-Term Care; Procarbazine; Ti | 1973 |
[Influencing of side-effects of cytostatic drugs using metoclopramide].
Topics: Amides; Anisoles; Antineoplastic Agents; Benzoates; Carcinoma; Ethylamines; Hodgkin Disease; Humans; | 1973 |
Updated Hodgkin's disease. C. Advanced disease and special problems. Comment: the non-Hodgkin's lymphomas.
Topics: Burkitt Lymphoma; Cyclophosphamide; Hodgkin Disease; Humans; Leukemia; Lymphoma; Lymphoma, Large B-C | 1973 |
Combination chemotherapy of acute leukemia and Hodgkin's disease.
Topics: Antineoplastic Agents; Drug Combinations; Hodgkin Disease; Humans; Leukemia; Mechlorethamine; Predni | 1972 |
The effects of leukemia and lymphoma chemotherapy on hematopoietic cells.
Topics: Alkylating Agents; Antimetabolites; Antineoplastic Agents; Asparaginase; Cell Division; Daunorubicin | 1973 |
[Hairy cell leukaemia clinical, light- and electronmicroscopical findings (author's transl)].
Topics: Adult; Agranulocytosis; Anemia, Aplastic; Anemia, Pernicious; Antibody Formation; Blood Platelets; C | 1974 |