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procarbazine and Leishmaniasis, Visceral

procarbazine has been researched along with Leishmaniasis, Visceral in 2 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Leishmaniasis, Visceral: A chronic disease caused by LEISHMANIA DONOVANI and transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. The disease is classified into three main types according to geographic distribution: Indian, Mediterranean (or infantile), and African.

Research Excerpts

ExcerptRelevanceReference
"A case of Hodgkin's disease associated from the start with visceral leishmaniasis in the absence of antitumoral treatment shows that leishmaniasis is a severe opportunistic infection in endemic areas and can be masked by the tumoral syndrome of an underlying pathology."2.38[Visceral leishmaniasis associated with Hodgkin's disease: diagnostic difficulties]. ( Blanc, AP; Jacquème, P; Magnan, A; Poirier, R; Redding, E; Sudan, N, 1991)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Magnan, A1
Jacquème, P1
Sudan, N1
Redding, E1
Blanc, AP1
Poirier, R1
Evans, AT1
Croft, SL1
Peters, W1
Neal, RA1

Reviews

1 review available for procarbazine and Leishmaniasis, Visceral

ArticleYear
[Visceral leishmaniasis associated with Hodgkin's disease: diagnostic difficulties].
    Revue de pneumologie clinique, 1991, Volume: 47, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antiprotozoal Agents; Bleomycin; Dacarbazine;

1991

Other Studies

1 other study available for procarbazine and Leishmaniasis, Visceral

ArticleYear
Hydrazide antidepressants possess novel antileishmanial activity in vitro and in vivo.
    Annals of tropical medicine and parasitology, 1989, Volume: 83, Issue:1

    Topics: Animals; Carbidopa; Drug Evaluation, Preclinical; Drug Interactions; Leishmania donovani; Leishmania

1989