procarbazine has been researched along with Intradural-Extramedullary Spinal Cord Neoplasms in 8 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Between May 1992 and January 1998, eight children with unresectable or recurrent intramedullary glioma were treated with the BB SFOP protocol (a 16-month chemotherapy regimen with carboplatin, procarbazine, vincristine, cyclophosphamide, etoposide and cisplatin)." | 5.09 | Chemotherapy for unresectable and recurrent intramedullary glial tumours in children. Brain Tumours Subcommittee of the French Society of Paediatric Oncology (SFOP). ( Chastagner, P; Chouffai, Z; Couanet, D; Doireau, V; Grignon, Y; Grill, J; Kalifa, C; Lellouch-Tubiana, A; Marchal, JC; Zerah, M, 1999) |
| "Procarbazine was not given as a specified protocol, but for patients who were ineligible or refused other protocols." | 2.38 | Reevaluation of procarbazine for the treatment of recurrent malignant central nervous system tumors. ( Levin, VA; Prados, M; Rodriguez, LA; Silver, P, 1989) |
| "Two cases of malignant schwannoma are reported 13 and 15 years following combined modality treatment for Hodgkin's disease." | 1.29 | Malignant schwannoma following treatment for Hodgkin's disease. ( Bridges, LR; Cartwright, SC; Dodwell, DJ; Fisher, PM; Stone, J, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ater, JL | 1 |
| Zhou, T | 1 |
| Holmes, E | 1 |
| Mazewski, CM | 1 |
| Booth, TN | 1 |
| Freyer, DR | 1 |
| Lazarus, KH | 1 |
| Packer, RJ | 1 |
| Prados, M | 2 |
| Sposto, R | 1 |
| Vezina, G | 1 |
| Wisoff, JH | 1 |
| Pollack, IF | 1 |
| Fisher, PM | 1 |
| Dodwell, DJ | 1 |
| Bridges, LR | 1 |
| Cartwright, SC | 1 |
| Stone, J | 1 |
| Doireau, V | 1 |
| Grill, J | 1 |
| Zerah, M | 1 |
| Lellouch-Tubiana, A | 1 |
| Couanet, D | 1 |
| Chastagner, P | 1 |
| Marchal, JC | 1 |
| Grignon, Y | 1 |
| Chouffai, Z | 1 |
| Kalifa, C | 1 |
| Henson, JW | 1 |
| Thornton, AF | 1 |
| Louis, DN | 1 |
| Rodriguez, LA | 1 |
| Silver, P | 1 |
| Levin, VA | 1 |
| Gershanovich, ML | 1 |
| Arkhipov, AI | 1 |
| Vilenskiĭ, BS | 1 |
| Lyding, JM | 1 |
| Tseng, A | 1 |
| Newman, A | 1 |
| Collins, S | 1 |
| Shea, W | 1 |
| Gurney, HP | 1 |
| Phadke, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Chemotherapy for Progressive Low Grade Astrocytoma in Children Less Than Ten Years Old[NCT00002944] | Phase 3 | 428 participants (Actual) | Interventional | 1997-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for procarbazine and Intradural-Extramedullary Spinal Cord Neoplasms
| Article | Year |
|---|---|
Reevaluation of procarbazine for the treatment of recurrent malignant central nervous system tumors.
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Child; Child, Preschool; Female; Glioblastoma; Glioma; Hum | 1989 |
2 trials available for procarbazine and Intradural-Extramedullary Spinal Cord Neoplasms
| Article | Year |
|---|---|
Randomized study of two chemotherapy regimens for treatment of low-grade glioma in young children: a report from the Children's Oncology Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Central Nervous System | 2012 |
Chemotherapy for unresectable and recurrent intramedullary glial tumours in children. Brain Tumours Subcommittee of the French Society of Paediatric Oncology (SFOP).
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Carboplatin; Chemotherapy, Adjuvant; Ch | 1999 |
5 other studies available for procarbazine and Intradural-Extramedullary Spinal Cord Neoplasms
| Article | Year |
|---|---|
Malignant schwannoma following treatment for Hodgkin's disease.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Combined Modality Therapy; Female | 1994 |
Spinal cord astrocytoma: response to PCV chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Biopsy; Fatal Outcome; Humans; L | 2000 |
[Use of nitrosourea derivatives in the treatment of patients with Hodgkin's disease with lesions of the central nervous system].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Drug Evaluation; | 1988 |
Intramedullary spinal cord metastasis in Hodgkin's disease. Rapid diagnosis and treatment resulting in neurologic recovery.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Hodgkin Di | 1987 |
Hodgkin's disease presenting with central nervous system involvement.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Hodgkin Disease; Humans; Mal | 1987 |