Page last updated: 2024-11-03

procarbazine and Infections

procarbazine has been researched along with Infections in 10 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Infections: Invasion of the host organism by microorganisms or their toxins or by parasites that can cause pathological conditions or diseases.

Research Excerpts

ExcerptRelevanceReference
"The clinical efficacy of COP-BLAM chemotherapy combined with human recombinant granulocyte colony-stimulating factor (G-CSF) was evaluated in 104 previously untreated patients with non-Hodgkin's lymphoma (NHL)."2.68COP-BLAM regimen combined with granulocyte colony-stimulating factor and high-grade non-Hodgkin's lymphoma. ( Niitsu, N; Umeda, M, 1995)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19906 (60.00)18.7374
1990's4 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Engelhard, M1
Gerhartz, H1
Brittinger, G1
Engert, A1
Fuchs, R1
Geiseler, B1
Gerhartz, D1
Haunauske, AR1
Hartlapp, HJ1
Huhn, D1
Niitsu, N1
Umeda, M1
Barai, U1
Teoh, N1
Aisenberg, AC1
Rowland, KM1
Murthy, A1
Popowniak, KL1
Nakamoto, S1
Konrad, H1
Engelmann, C1
Zubaidi, G1
Stenzel, L1
Krug, K1
Schingnitz, G1
Rodriguez, V1
Bodey, GP1
Freireich, EJ1
Smith, KL1
Johnson, D1
Hustu, O1
Pratt, C1
Fleming, I1
Holton, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Late Treatment Effects in Long-Term Survivors of Hodgkin's Disease Previously Treated at NIH: A Multi-Institutional Trial[NCT00924131]157 participants (Anticipated)Observational2009-04-17Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for procarbazine and Infections

ArticleYear
Problems in Hodgkin's disease management.
    Blood, 1999, Feb-01, Volume: 93, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplant

1999
Hodgkin's disease: long-term effects of therapy.
    Medical and pediatric oncology, 1986, Volume: 14, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Brain; Female; Genitalia, Fem

1986
Immunosuppressive therapy in renal transplantation.
    The Surgical clinics of North America, 1971, Volume: 51, Issue:5

    Topics: Adolescent; Adult; Animals; Anticoagulants; Antigens; Antilymphocyte Serum; Asparaginase; Azathiopri

1971
Combination chemotherapy for lymphomas and leukemias.
    Disease-a-month : DM, 1973

    Topics: Adult; Burkitt Lymphoma; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Combinations; Hodgk

1973

Trials

3 trials available for procarbazine and Infections

ArticleYear
Cytokine efficiency in the treatment of high-grade malignant non-Hodgkin's lymphomas: results of a randomized double-blind placebo-controlled study with intensified COP-BLAM +/- rhGM-CSF.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1994, Volume: 5 Suppl 2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit

1994
COP-BLAM regimen combined with granulocyte colony-stimulating factor and high-grade non-Hodgkin's lymphoma.
    European journal of haematology, 1995, Volume: 55, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomyci

1995
Multiple statistics for multiple events, with application to repeated infections in the growth factor studies.
    Statistics in medicine, 1997, Apr-30, Volume: 16, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Drug Thera

1997

Other Studies

3 other studies available for procarbazine and Infections

ArticleYear
[Cytostatic therapy of lymphogranulomatosis].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1972, Dec-01, Volume: 27, Issue:23

    Topics: Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Chlorambucil; Cyclophosphamide; Cysti

1972
[Results of polychemotherapy in neoplasms of the lymphoreticular system].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1973, May-01, Volume: 28, Issue:9

    Topics: Antineoplastic Agents; Cyclophosphamide; Hodgkin Disease; Humans; Infections; Leukopenia; Long-Term

1973
Concurrent chemotherapy and radiation therapy in the treatment of childhood and adolescent Hodgkin's disease.
    Cancer, 1974, Volume: 33, Issue:1

    Topics: Adolescent; Adult; Age Factors; Alopecia; Child; Child, Preschool; Cobalt Radioisotopes; Cyclophosph

1974