procarbazine has been researched along with Hypogonadism in 1 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Hypogonadism: Condition resulting from deficient gonadal functions, such as GAMETOGENESIS and the production of GONADAL STEROID HORMONES. It is characterized by delay in GROWTH, germ cell maturation, and development of secondary sex characteristics. Hypogonadism can be due to a deficiency of GONADOTROPINS (hypogonadotropic hypogonadism) or due to primary gonadal failure (hypergonadotropic hypogonadism).
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient with hypogonadotropic hypogonadism owing to endogenous gonadotropin releasing hormone deficiency, who developed Hodgkin's disease is described." | 1.28 | Is androgen substitution necessary in hypogonadal patients when they are treated with chemotherapy for malignant diseases? ( Nikolaou, N; Orfanos, S; Pavlidis, N; Tolis, C; Tolis, G, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pavlidis, N | 1 |
| Nikolaou, N | 1 |
| Tolis, C | 1 |
| Orfanos, S | 1 |
| Tolis, G | 1 |
1 other study available for procarbazine and Hypogonadism
| Article | Year |
|---|---|
Is androgen substitution necessary in hypogonadal patients when they are treated with chemotherapy for malignant diseases?
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Diseases; Hodgkin Dis | 1989 |