procarbazine has been researched along with Histiocytosis, Langerhans-Cell in 8 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Histiocytosis, Langerhans-Cell: A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic Birbeck granules (X bodies), or by monoclonal antibody staining for their surface CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The overall 38% response rate in histiocytosis X for cyclophosphamide, vincristine (Oncovin), prednisone, and procarbazine was not superior to responses that can be achieved with the component single agents." | 2.64 | Evaluation of a MOPP-type regimen in histiocytosis X--a Southwest Oncology Group study. ( Herson, J; Komp, DM; Miale, T; Sexauer, C; Silva-Sosa, M, 1977) |
| "We describe two cases of Hodgkin's disease after heart and heart/lung transplants respectively." | 1.29 | Hodgkin's disease after cardiac transplant: a report of two cases. ( Hood, IM; Mahendra, P; Marcus, RE; McNeil, K, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haefliger, S | 1 |
| Bihl, M | 1 |
| Krasniqi, F | 1 |
| Tzankov, A | 1 |
| Régis, A | 1 |
| Ben Salem, D | 1 |
| Lambert, A | 1 |
| Couaillier, JF | 1 |
| Casasnovas, O | 1 |
| Piard, F | 1 |
| Krausé, D | 1 |
| Zemskova, VI | 2 |
| Hood, IM | 1 |
| Mahendra, P | 1 |
| McNeil, K | 1 |
| Marcus, RE | 1 |
| Komp, DM | 1 |
| Silva-Sosa, M | 1 |
| Miale, T | 1 |
| Sexauer, C | 1 |
| Herson, J | 1 |
| Makhonova, LA | 1 |
| Peterson, IS | 1 |
| Koposov, PV | 1 |
| Tupitsyn, NN | 1 |
| Shanley, DJ | 1 |
| Lerud, KS | 1 |
| Luetkehans, TJ | 1 |
| Rivera-Luna, R | 1 |
| Martinez-Guerra, G | 1 |
| Altamirano-Alvarez, E | 1 |
| Martinez-Avalos, A | 1 |
| Cardenas-Cardoz, R | 1 |
| Ayon-Cardenas, A | 1 |
| Ruiz-Maldonado, R | 1 |
| Lopez-Corella, E | 1 |
1 trial available for procarbazine and Histiocytosis, Langerhans-Cell
| Article | Year |
|---|---|
Evaluation of a MOPP-type regimen in histiocytosis X--a Southwest Oncology Group study.
Topics: Child; Child, Preschool; Clinical Trials as Topic; Cyclophosphamide; Drug Evaluation; Drug Therapy, | 1977 |
7 other studies available for procarbazine and Histiocytosis, Langerhans-Cell
| Article | Year |
|---|---|
PET-positive bone lesion due to Langerhans cell histiocytosis after BEACOPP therapy for Hodgkin lymphoma: how anamnesis, histopathological accuracy, and molecular analysis could resolve a clinical dilemma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Bone Marrow; Causality | 2018 |
[Concomitant pulmonary Langerhans cell histiocytosis and malignant lymphoma: report of two cases].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bleomycin; Combined Modality Therapy; | 2009 |
[Chemotherapy in the treatment program for histiocytosis X in children].
Topics: Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cyclophosphamide; Drug Therapy, Co | 1983 |
Hodgkin's disease after cardiac transplant: a report of two cases.
Topics: Adult; Antibodies, Viral; Antineoplastic Combined Chemotherapy Protocols; Aspergillosis; Chlorambuci | 1996 |
[Histiocytic proliferative diseases in children].
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Pre | 1992 |
Development of pulmonary histiocytosis X after chemotherapy for Hodgkin disease.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Dacarbazine; Doxorubicin; Fem | 1990 |
Langerhans cell histiocytosis: clinical experience with 124 patients.
Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Diseases; Child; Child | 1988 |