procarbazine has been researched along with Histiocytic Sarcoma in 2 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Histiocytic Sarcoma: Malignant neoplasms composed of MACROPHAGES or DENDRITIC CELLS. Most histiocytic sarcomas present as localized tumor masses without a leukemic phase. Though the biological behavior of these neoplasms resemble lymphomas, their cell lineage is histiocytic not lymphoid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The diagnostic findings of malignant histiocytosis (MH) were analysed in 12 consecutive patients in a single institution." | 1.28 | Clinicopathological diagnosis and treatment of malignant histiocytosis. ( Abels, J; Kappers-Klunne, M; Prins, ME; Sonneveld, P; van Lom, K, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sonneveld, P | 1 |
| van Lom, K | 1 |
| Kappers-Klunne, M | 1 |
| Prins, ME | 1 |
| Abels, J | 1 |
| Bonetti, F | 1 |
| Chilosi, M | 1 |
| Menestrina, F | 1 |
| Lestani, M | 1 |
| Scarpa, A | 1 |
| Todeschini, G | 1 |
| Pizzolo, G | 1 |
| Fiore-Donati, L | 1 |
2 other studies available for procarbazine and Histiocytic Sarcoma
| Article | Year |
|---|---|
Clinicopathological diagnosis and treatment of malignant histiocytosis.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Fe | 1990 |
Blastic OKT6-positive proliferation preceding malignant histiocytosis.
Topics: Antigens, Differentiation, T-Lymphocyte; Antineoplastic Combined Chemotherapy Protocols; Histiocytic | 1986 |