Page last updated: 2024-11-03

procarbazine and Hematologic Neoplasms

procarbazine has been researched along with Hematologic Neoplasms in 7 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Hematologic Neoplasms: Neoplasms located in the blood and blood-forming tissue (the bone marrow and lymphatic tissue). The commonest forms are the various types of LEUKEMIA, of LYMPHOMA, and of the progressive, life-threatening forms of the MYELODYSPLASTIC SYNDROMES.

Research Excerpts

ExcerptRelevanceReference
"Acquired ichthyosis is a rare condition that can reveal an unsuspected haematological malignancy, thus allowing early diagnosis and management."1.38[Acquired ichthyosis and haematological malignancies: five cases]. ( Baybay, H; Berrady, R; Bono, W; El Hatimi, A; Gallouj, S; Khammar, Z; Lahlou, M; Lamchachti, L; Mernissi, FZ, 2012)
"Procarbazine (PCB) was developed in the 1960s and was rapidly recognised as an active agent in lymphoid malignancies."1.32Procarbazine in haematology: an old drug with a new life? ( Armand, JP; Massoud, M; Ribrag, V, 2004)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berrady, R1
Baybay, H1
Khammar, Z1
Lahlou, M1
Lamchachti, L1
Gallouj, S1
El Hatimi, A1
Mernissi, FZ1
Bono, W1
Rancea, M1
Skoetz, N1
Monsef, I1
Hübel, K1
Engert, A2
Bauer, K1
Ogawa, M1
Massoud, M1
Armand, JP1
Ribrag, V1
Kober, T1
Hülsewede, H1
Bohlius, J1
Niitsu, N1
Kato, M1
Shikoshi, K1
Umeda, M1
Howell, SJ1
Radford, JA1
Adams, JE1
Shalet, SM1

Reviews

3 reviews available for procarbazine and Hematologic Neoplasms

ArticleYear
Fourteenth biannual report of the Cochrane Haematological Malignancies Group--focus on autologous stem cell transplantation in hematological malignancies.
    Journal of the National Cancer Institute, 2012, Jul-18, Volume: 104, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Colony-Stimulating Factors; Cyclophospham

2012
[Hematologic tumors].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cytarabine; Dacarbazine

2003
Fourth biannual report of the Cochrane Haematological Malignancies Group.
    Journal of the National Cancer Institute, 2006, Apr-19, Volume: 98, Issue:8

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy

2006

Other Studies

4 other studies available for procarbazine and Hematologic Neoplasms

ArticleYear
[Acquired ichthyosis and haematological malignancies: five cases].
    Annales de dermatologie et de venereologie, 2012, Volume: 139, Issue:1

    Topics: Adult; Aged; Allopurinol; Anemia; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Ant

2012
Procarbazine in haematology: an old drug with a new life?
    European journal of cancer (Oxford, England : 1990), 2004, Volume: 40, Issue:13

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Drug Interactions; Drug Resis

2004
[Doxorubicin-induced myocardial damage in elderly patients with hematologic malignancies].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1997, Volume: 34, Issue:1

    Topics: Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols

1997
The impact of mild Leydig cell dysfunction following cytotoxic chemotherapy on bone mineral density (BMD) and body composition.
    Clinical endocrinology, 2000, Volume: 52, Issue:5

    Topics: Adult; Antineoplastic Agents; Body Composition; Bone Density; Bone Diseases, Metabolic; Case-Control

2000