procarbazine has been researched along with Heart Failure in 2 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Since the absorption rate is not clinically relevant in patients on long-term glycoside therapy, our results indicate that digitoxin is preferable to digoxin in such patients." | 1.26 | Cytostatic drugs are without significant effect on digitoxin plasma level and renal excretion. ( Kuhlmann, J; Rietbrock, N; Wilke, J, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kuhlmann, J | 1 |
| Wilke, J | 1 |
| Rietbrock, N | 1 |
| Harrison, DT | 1 |
| Neiman, PE | 1 |
| Sullivan, K | 1 |
| Hafermann, M | 1 |
| Rudolph, RH | 1 |
| Einstein, AB | 1 |
2 other studies available for procarbazine and Heart Failure
| Article | Year |
|---|---|
Cytostatic drugs are without significant effect on digitoxin plasma level and renal excretion.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabin | 1982 |
Combined modality therapy for advanced, diffuse lymphocytic and histiocytic lymphomas.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bone Marrow; Cyclophosphamide; Doxorubicin; Drug The | 1978 |