procarbazine has been researched along with Gynecomastia in 2 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Gynecomastia: Enlargement of the BREAST in the males, caused by an excess of ESTROGENS. Physiological gynecomastia is normally observed in NEWBORNS; ADOLESCENT; and AGING males.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gynecomastia was not associated with an increase in either serum estradiol or prolactin concentrations." | 1.26 | Gynecomastia and gonadal dysfunction in adolescent boys treated with combination chemotherapy for Hodgkin's disease. ( Olweny, CL; Sherins, RJ; Ziegler, JL, 1978) |
| "Between 1967 and 1977, 48 patients with Hodgkin's disease under 16-years-old were treated with MOPP chemotherapy alone at the Uganda Cancer Institute because radiotherapy facilities are not available." | 1.26 | Childhood Hodgkin's disease in Uganda: a ten year experience. ( Katongole-Mbidde, E; Kiire, C; Lwanga, SK; Magrath, I; Olweny, CL; Ziegler, JL, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sherins, RJ | 1 |
| Olweny, CL | 2 |
| Ziegler, JL | 2 |
| Katongole-Mbidde, E | 1 |
| Kiire, C | 1 |
| Lwanga, SK | 1 |
| Magrath, I | 1 |
2 other studies available for procarbazine and Gynecomastia
| Article | Year |
|---|---|
Gynecomastia and gonadal dysfunction in adolescent boys treated with combination chemotherapy for Hodgkin's disease.
Topics: Adolescent; Age Factors; Antineoplastic Agents; Child; Child, Preschool; Drug Therapy, Combination; | 1978 |
Childhood Hodgkin's disease in Uganda: a ten year experience.
Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Gynec | 1978 |