Page last updated: 2024-11-03

procarbazine and Granulomas

procarbazine has been researched along with Granulomas in 5 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Research Excerpts

ExcerptRelevanceReference
" Tumours only appeared in those animals in which growth of the granuloma tissue was stimulated with a dose of croton oil."3.66Single dose carcinogenicity of procarbazine in rats. ( Maier, P; Zbinden, G, 1983)
"Subsequently, standard chemotherapy for Hodgkin's disease induced complete clinical and biochemical remission."1.29Suspected malignant lymphoma presenting with widespread granulomatous lesions in bones and lymph nodes and responding to combination chemotherapy. ( Jensen, MK; Johansen, P; Pulczynski, S, 1996)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Isobe, T1
Umemoto, J1
Kobayashi, M1
Okuno, T1
Shiratsuki, Y1
Kodama, A1
Nakao, M1
Amano, Y1
Hotta, T1
Hamaguchi, M1
Okimoto, T1
Hamaguchi, S1
Tsubata, Y1
Zbinden, G1
Maier, P1
Jensen, MK1
Pulczynski, S1
Johansen, P1
Wakem, CJ1
Bennett, JM1
Garrie, SA1
Hirsch, P1
Levan, N1

Other Studies

5 other studies available for procarbazine and Granulomas

ArticleYear
Varicella-zoster Virus Related Pulmonary Granulomas in Which Varicella-zoster Virus DNA Was Demonstrated in a Thoracoscopic Lung Biopsy Specimen.
    Internal medicine (Tokyo, Japan), 2019, Jul-15, Volume: 58, Issue:14

    Topics: Acyclovir; Adult; Antiviral Agents; Cyclophosphamide; DNA, Viral; Granuloma; Humans; Male; Pneumonia

2019
Single dose carcinogenicity of procarbazine in rats.
    Cancer letters, 1983, Volume: 21, Issue:2

    Topics: Adenoma; Air; Animals; Carcinoma; Croton Oil; Fibrosarcoma; Granuloma; Injections, Intraperitoneal;

1983
Suspected malignant lymphoma presenting with widespread granulomatous lesions in bones and lymph nodes and responding to combination chemotherapy.
    Acta haematologica, 1996, Volume: 96, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone and Bones; Chlorambucil; Diagnosis, Differentia

1996
Hodgkin's disease terminating as acute leukaemia: case report and review of the literature.
    The New Zealand medical journal, 1972, Volume: 76, Issue:484

    Topics: Acute Disease; Adolescent; Adult; Bone Marrow; Female; Granuloma; Hodgkin Disease; Humans; Leukemia,

1972
Granuloma annulare-like pattern in mycosis fungoides.
    Archives of dermatology, 1972, Volume: 105, Issue:5

    Topics: Biopsy; Granuloma; Humans; Male; Methotrexate; Microscopy, Electron; Middle Aged; Mycosis Fungoides;

1972