procarbazine has been researched along with Graft vs Host Disease in 11 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Graft vs Host Disease: The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eight patients with disseminated Hodgkin's disease resistant to MOPP (mechlorethamine, vincristine, procarbazine, and prednisone) chemotherapy were treated with high-dose chemoradiotherapy and marrow transplantation from an HLA-identical sibling." | 1.27 | Allogeneic marrow transplantation in the treatment of MOPP-resistant Hodgkin's disease. ( Appelbaum, FR; Buckner, CD; Clift, RA; Deeg, HJ; Neiman, PE; Sanders, JE; Stewart, P; Storb, R; Sullivan, KM; Thomas, ED, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (54.55) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kharfan-Dabaja, MA | 1 |
| Cutler, CS | 1 |
| Mian, M | 1 |
| Farsad, M | 1 |
| Pescosta, N | 1 |
| Casini, M | 1 |
| Cavattoni, IM | 1 |
| Deola, S | 1 |
| Cortelazzo, S | 1 |
| Rancea, M | 1 |
| Skoetz, N | 1 |
| Monsef, I | 1 |
| Hübel, K | 1 |
| Engert, A | 1 |
| Bauer, K | 1 |
| Mandigers, CM | 1 |
| Verdonck, LF | 1 |
| Meijerink, JP | 1 |
| Dekker, AW | 1 |
| Schattenberg, AV | 1 |
| Raemaekers, JM | 1 |
| Burns, LJ | 1 |
| Westberg, MW | 1 |
| Burns, CP | 1 |
| Klassen, LW | 1 |
| Goeken, NE | 1 |
| Ray, TL | 1 |
| Macfarlane, DE | 1 |
| Min, CK | 1 |
| Kim, DW | 1 |
| Lee, JW | 1 |
| Han, CW | 1 |
| Min, WS | 1 |
| Kim, CC | 1 |
| Appelbaum, FR | 1 |
| Sullivan, KM | 1 |
| Thomas, ED | 1 |
| Buckner, CD | 1 |
| Clift, RA | 1 |
| Deeg, HJ | 1 |
| Neiman, PE | 1 |
| Sanders, JE | 1 |
| Stewart, P | 1 |
| Storb, R | 1 |
| Smith, BR | 2 |
| Guinan, EC | 1 |
| Parkman, R | 1 |
| Ferrara, J | 1 |
| Levey, RH | 1 |
| Nathan, DG | 2 |
| Rappeport, JM | 2 |
| Antin, JH | 1 |
| Ginsburg, D | 1 |
| Orkin, SH | 1 |
| Floersheim, GL | 1 |
| Glucksberg, H | 1 |
| Fefer, A | 1 |
2 reviews available for procarbazine and Graft vs Host Disease
| Article | Year |
|---|---|
Rituximab for prevention and treatment of graft-versus-host disease.
Topics: Adrenal Cortex Hormones; Adult; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chem | 2011 |
Fourteenth biannual report of the Cochrane Haematological Malignancies Group--focus on autologous stem cell transplantation in hematological malignancies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Colony-Stimulating Factors; Cyclophospham | 2012 |
9 other studies available for procarbazine and Graft vs Host Disease
| Article | Year |
|---|---|
Bendamustine salvage for the treatment of relapsed Hodgkin's lymphoma after allogeneic bone marrow transplantation.
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents, Alkylating; Antineoplastic Combined C | 2013 |
Graft-versus-lymphoma effect of donor lymphocyte infusion in indolent lymphomas relapsed after allogeneic stem cell transplantation.
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemo | 2003 |
Acute graft-versus-host disease resulting from normal donor blood transfusions.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Graft vs Host Disease; Histocompatibi | 1984 |
Supplemental peripheral blood stem cells to decrease marrow rejection in adult patients with severe aplastic anemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Antigens, CD34; Antilymphocyte Serum; Bone Marrow Transplantati | 2002 |
Allogeneic marrow transplantation in the treatment of MOPP-resistant Hodgkin's disease.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplantation; Combi | 1985 |
Efficacy of a cyclophosphamide-procarbazine-antithymocyte serum regimen for prevention of graft rejection following bone marrow transplantation for transfused patients with aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Blood Transfusion; Bone Marrow Transplantation; Cyclophospha | 1985 |
Bone marrow transplantation for paroxysmal nocturnal hemoglobinuria: eradication of the PNH clone and documentation of complete lymphohematopoietic engraftment.
Topics: Adult; Antilymphocyte Serum; Base Sequence; Blood Grouping and Crossmatching; Bone Marrow Transplant | 1985 |
Treatment of hyperacute graft-versus-host disease in mice with cytosine arabinoside.
Topics: Acute Disease; Animals; Antilymphocyte Serum; Cyclophosphamide; Cytarabine; Graft vs Host Disease; G | 1972 |
Chemotherapy of established graft-versus-host disease in mice.
Topics: Animals; Benzoates; Cyclophosphamide; Disease Models, Animal; Graft vs Host Disease; Immunosuppressi | 1972 |