procarbazine has been researched along with Fibrosarcoma in 3 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Fibrosarcoma: A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Tumours only appeared in those animals in which growth of the granuloma tissue was stimulated with a dose of croton oil." | 3.66 | Single dose carcinogenicity of procarbazine in rats. ( Maier, P; Zbinden, G, 1983) |
| "Patients who survive Hodgkin lymphoma (HL) are at increased risk of secondary neoplasms (SNs)." | 1.43 | Secondary Neoplasms in Children with Hodgkin's Lymphoma Receiving C-MOPP and Radiotherapy: Presentation of Four Cases. ( Çavdar, A; Ceyhan, K; Deda, H; Gökçora, İH; Gözdaşoğlu, S; Işıkman, E; Pamir, A; Taçyıldız, N; Uluoğlu, Ö; Ünal, E; Yavuz, G, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gözdaşoğlu, S | 1 |
| Pamir, A | 1 |
| Ünal, E | 1 |
| Gökçora, İH | 1 |
| Uluoğlu, Ö | 1 |
| Ceyhan, K | 1 |
| Deda, H | 1 |
| Işıkman, E | 1 |
| Yavuz, G | 1 |
| Taçyıldız, N | 1 |
| Çavdar, A | 1 |
| Zbinden, G | 1 |
| Maier, P | 1 |
| Arseneau, JC | 1 |
| Sponzo, RW | 1 |
| Levin, DL | 1 |
| Schnipper, LE | 1 |
| Bonner, H | 1 |
| Young, RC | 1 |
| Canellos, GP | 1 |
| Johnson, RE | 1 |
| DeVita, VT | 1 |
3 other studies available for procarbazine and Fibrosarcoma
| Article | Year |
|---|---|
Secondary Neoplasms in Children with Hodgkin's Lymphoma Receiving C-MOPP and Radiotherapy: Presentation of Four Cases.
Topics: Adenoma; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Du | 2016 |
Single dose carcinogenicity of procarbazine in rats.
Topics: Adenoma; Air; Animals; Carcinoma; Croton Oil; Fibrosarcoma; Granuloma; Injections, Intraperitoneal; | 1983 |
Nonlymphomatous malignant tumors complicating Hodgkin's disease. Possible association with intensive therapy.
Topics: Adolescent; Adult; Antineoplastic Agents; Carcinoma, Squamous Cell; Cyclophosphamide; Drug-Related S | 1972 |