procarbazine has been researched along with Fetal Growth Retardation in 2 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Fetal Growth Retardation: Failure of a FETUS to attain expected GROWTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the effects of prenatal folic acid supplementation on procarbazine (PCZ)-induced intra-uterine growth retardation (IUGR), cleft palates, and microgenia." | 7.72 | Reduction of procarbazine-induced cleft palates by prenatal folic acid supplementation in rats. ( Bienengräber, V; Fanghänel, J; Malek, FA; Möritz, KU, 2004) |
| "We investigated the effects of prenatal folic acid supplementation on procarbazine (PCZ)-induced intra-uterine growth retardation (IUGR), cleft palates, and microgenia." | 3.72 | Reduction of procarbazine-induced cleft palates by prenatal folic acid supplementation in rats. ( Bienengräber, V; Fanghänel, J; Malek, FA; Möritz, KU, 2004) |
| "Because several previous authors have repeatedly described treatment with thiamine as one of the sufficient prophylactic measures in slowing the development of viscerocranial malformations, especially cleft alveolus and palate, it is of utmost importance that the timing of treatment and dosage of thiamine be taken into consideration not only in animal experiments but also when applying results to humans." | 1.30 | Application of thiamine in preventing malformations, specifically cleft alveolus and palate, during the intrauterine development of rats. ( Bienengräber, V; Fanghänel, J; Kundt, G; Malek, FA, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Malek, FA | 2 |
| Möritz, KU | 1 |
| Fanghänel, J | 2 |
| Bienengräber, V | 2 |
| Kundt, G | 1 |
2 other studies available for procarbazine and Fetal Growth Retardation
| Article | Year |
|---|---|
Reduction of procarbazine-induced cleft palates by prenatal folic acid supplementation in rats.
Topics: Animals; Antineoplastic Agents; Cleft Palate; Dietary Supplements; Disease Models, Animal; Dose-Resp | 2004 |
Application of thiamine in preventing malformations, specifically cleft alveolus and palate, during the intrauterine development of rats.
Topics: Abnormalities, Drug-Induced; Alveolar Process; Animals; Body Weight; Bone and Bones; Cleft Palate; C | 1997 |