Page last updated: 2024-11-03

procarbazine and Enlarged Spleen

procarbazine has been researched along with Enlarged Spleen in 9 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Research Excerpts

ExcerptRelevanceReference
" Results of axillary lymph node, skin, and bone-marrow biopsies led to the diagnosis of angioimmunoblastic T-cell lymphoma (AITL), for which CEPP therapy (cyclophosphamide, etoposide, procarbazine, and prednisolone) was initiated."3.88Emergence of anti-mitochondrial M2 antibody in patient with angioimmunoblastic T-cell lymphoma. ( Hiroshima, Y; Joshita, S; Kawata, K; Kimura, T; Kobayashi, H; Mori, H; Tanaka, E; Tanaka, N; Umemura, T; Wada, S; Wakabayashi, SI, 2018)
"Multivariate analysis retained enlarged spleen, involvement of three or more lymph node areas, and bulky disease as significant risk factors for spleen involvement."1.32Significance of splenomegaly in childhood Hodgkin disease. ( Arya, LS; Bakhshi, S; Dawar, R; Dinand, V; Singh, R; Thavaraj, V, 2004)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
O'Bryen, J1
Anderson, NR1
Collins, J1
Wakabayashi, SI1
Kimura, T1
Tanaka, N1
Joshita, S1
Kawata, K1
Umemura, T1
Hiroshima, Y1
Mori, H1
Kobayashi, H1
Wada, S1
Tanaka, E1
Xing, PY1
Shi, YK1
He, XH1
Zhou, LQ1
Dong, M1
Yang, JL1
Liu, P1
Chakravorty, S1
Johnston, R1
Coulter, C1
Bain, BJ1
Arya, LS1
Dinand, V1
Bakhshi, S1
Thavaraj, V1
Singh, R1
Dawar, R1
Camitta, BM1
Quesenberry, PJ1
Parkman, R1
Boxer, LA1
Stossel, TP1
Cassady, JR1
Rappeport, JM1
Nathan, DG1
Virgolini, L1
Aisenberg, AC1
Qazi, R1
Düllmann, J1
Wulfhekel, U1
Drescher, S1
Hausmann, K1

Reviews

1 review available for procarbazine and Enlarged Spleen

ArticleYear
[Neutrophil leukemia. Review of the literature].
    Minerva medica, 1985, Oct-27, Volume: 76, Issue:41

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Examination; Busulfan; Fema

1985

Other Studies

8 other studies available for procarbazine and Enlarged Spleen

ArticleYear
Heart on the wrong side.
    Australian journal of general practice, 2019, Volume: 48, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dacarbazine; Doxorubici

2019
Emergence of anti-mitochondrial M2 antibody in patient with angioimmunoblastic T-cell lymphoma.
    Clinical journal of gastroenterology, 2018, Volume: 11, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Cyclophosphamide; Etoposide; F

2018
[Clinical analysis of childhood and adolescent Hodgkin's lymphoma: a report of 88 cases].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2012, Volume: 34, Issue:9

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Child, Preschool; Comb

2012
Teaching cases from the Royal Marsden and St Mary's Hospitals, case 26: refractory microcytic anaemia.
    Leukemia & lymphoma, 2004, Volume: 45, Issue:7

    Topics: Anemia, Refractory; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Bleomycin; Blood Sed

2004
Significance of splenomegaly in childhood Hodgkin disease.
    Journal of pediatric hematology/oncology, 2004, Volume: 26, Issue:12

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Child, Preschool; Cycl

2004
Bone marrow transplantation for an infant with neutrophil dysfunction.
    Experimental hematology, 1977, Volume: 5, Issue:2

    Topics: Antilymphocyte Serum; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; Cell Division; Cl

1977
Abdominal involvement at the onset of Hodgkin's disease.
    The American journal of medicine, 1974, Volume: 57, Issue:6

    Topics: Alkaline Phosphatase; Axilla; Hodgkin Disease; Humans; Laparotomy; Lymph Nodes; Lymphography; Medias

1974
[Hairy cell leukaemia clinical, light- and electronmicroscopical findings (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Apr-26, Volume: 99, Issue:17

    Topics: Adult; Agranulocytosis; Anemia, Aplastic; Anemia, Pernicious; Antibody Formation; Blood Platelets; C

1974