procarbazine has been researched along with Embryopathies in 2 studies
Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, folic acid was tested for its antiteratogenic effects on experimentally induced cleft palate in animals." | 7.71 | Is it possible to prevent cleft palate by prenatal administration of folic acid? An experimental study. ( Bienengräber, V; Fanghänel, J; Gundlach, KK; Malek, FA; Möritz, KU; Weingärtner, J, 2001) |
| "In this study, folic acid was tested for its antiteratogenic effects on experimentally induced cleft palate in animals." | 3.71 | Is it possible to prevent cleft palate by prenatal administration of folic acid? An experimental study. ( Bienengräber, V; Fanghänel, J; Gundlach, KK; Malek, FA; Möritz, KU; Weingärtner, J, 2001) |
| "Because several previous authors have repeatedly described treatment with thiamine as one of the sufficient prophylactic measures in slowing the development of viscerocranial malformations, especially cleft alveolus and palate, it is of utmost importance that the timing of treatment and dosage of thiamine be taken into consideration not only in animal experiments but also when applying results to humans." | 1.30 | Application of thiamine in preventing malformations, specifically cleft alveolus and palate, during the intrauterine development of rats. ( Bienengräber, V; Fanghänel, J; Kundt, G; Malek, FA, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bienengräber, V | 2 |
| Fanghänel, J | 2 |
| Malek, FA | 2 |
| Kundt, G | 1 |
| Möritz, KU | 1 |
| Gundlach, KK | 1 |
| Weingärtner, J | 1 |
2 other studies available for procarbazine and Embryopathies
| Article | Year |
|---|---|
Application of thiamine in preventing malformations, specifically cleft alveolus and palate, during the intrauterine development of rats.
Topics: Abnormalities, Drug-Induced; Alveolar Process; Animals; Body Weight; Bone and Bones; Cleft Palate; C | 1997 |
Is it possible to prevent cleft palate by prenatal administration of folic acid? An experimental study.
Topics: Animals; Chin; Cleft Palate; Female; Fetal Diseases; Folic Acid; Pilot Projects; Pregnancy; Procarba | 2001 |