Page last updated: 2024-11-03

procarbazine and Disease Exacerbation

procarbazine has been researched along with Disease Exacerbation in 79 studies

Procarbazine: An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
procarbazine : A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.

Research Excerpts

ExcerptRelevanceReference
"To conduct a Phase II study to evaluate the long-term efficacy and safety of high-dose 5'-bromodeoxyuridine (BrdU) and accelerated radiotherapy followed by procarbazine, lomustine (CCNU), and vincristine (PCV) chemotherapy in patients with glioblastoma multiforme."9.09A phase II trial of high-dose bromodeoxyuridine with accelerated fractionation radiotherapy followed by procarbazine, lomustine, and vincristine for glioblastoma multiforme. ( Bruner, JM; Groves, MD; Hess, K; Jaeckle, KA; Kyritsis, AP; Levin, VA; Maor, MH; Meyers, C; Peterson, P; Sawaya, RE; Yung, WK, 1999)
"To determine whether chemotherapy with temozolomide (TMZ) versus procarbazine (PCB) for recurrent glioblastoma multiforme (GBM) was associated with improvement in health-related quality of life (HRQOL)."9.09Health-related quality of life in patients treated with temozolomide versus procarbazine for recurrent glioblastoma multiforme. ( Brada, M; Osoba, D; Prados, M; Yung, WK, 2000)
" The relative safety of accelerated fractionated radiotherapy, as used in this study with carboplatin, enables concomitant full-dose administration of chemotherapy or radiosensitizing agents in glioblastoma multiforme patients."9.08Phase II study of accelerated fractionation radiation therapy with carboplatin followed by vincristine chemotherapy for the treatment of glioblastoma multiforme. ( Bruner, J; Kyritsis, AP; Leeds, N; Levin, VA; Maor, MH; Rodriguez, L; Sawaya, R; Thall, PF; Woo, S; Yung, WK, 1995)
"To assess the effectiveness and safety of procarbazine, lomustine, and vincristine (PCV) chemotherapy with other interventions in adults with recurrent high-grade glioma."8.95Procarbazine, lomustine and vincristine for recurrent high-grade glioma. ( Guo, J; Parasramka, S; Rosenfeld, M; Talari, G; Villano, JL, 2017)
" In this paper we address different clinical outcomes measures separately and we illustrate the value of multiple outcome measures using the results of a recent clinical trial comparing temozolomide with procarbazine in the treatment of Glioblastoma Multiforme."8.82Benefit of temozolomide compared to procarbazine in treatment of glioblastoma multiforme at first relapse: effect on neurological functioning, performance status, and health related quality of life. ( Kiebert, G; Macdonald, DR; Olson, J; Prados, M; Yung, A, 2005)
" When treated with temozolomide (TMZ), an oral alkylating chemotherapy drug, most low-grade gliomas (LGG) show an initial volume decrease but this effect is rarely long lasting."7.85Analysis of temozolomide resistance in low-grade gliomas using a mechanistic mathematical model. ( Alentorn, A; Delattre, JY; Ducray, F; Grenier, E; Honnorat, J; Idbaih, A; Kaloshi, G; Mazzocco, P; Ollier, E; Psimaras, D; Ricard, D; Samson, A, 2017)
"To determine the efficacy of the combination of 6-thioguanine, procarbazine, lomustine, and hydroxyurea for patients with recurrent malignant gliomas after failure of either previous radiotherapy alone or previous radiotherapy plus nitrosourea-based chemotherapy."7.69Combination of 6-thioguanine, procarbazine, lomustine, and hydroxyurea for patients with recurrent malignant gliomas. ( Bruner, J; Flowers, A; Gleason, MJ; Ictech, SE; Jaeckle, KA; Kyritsis, AP; Levin, VA; Yung, WK, 1996)
"Cilengitide was continued for up to 12 months or until disease progression or unacceptable toxicity."6.82Cilengitide with metronomic temozolomide, procarbazine, and standard radiotherapy in patients with glioblastoma and unmethylated MGMT gene promoter in ExCentric, an open-label phase II trial. ( Ackland, S; Back, M; Buyse, ME; Kerestes, Z; Khasraw, M; Kichenadasse, G; Lee, A; McCowatt, S; Wheeler, H, 2016)
"Temozolomide was in general well tolerated; the most frequent side-effects were hematological."6.71Second-line chemotherapy with temozolomide in recurrent oligodendroglioma after PCV (procarbazine, lomustine and vincristine) chemotherapy: EORTC Brain Tumor Group phase II study 26972. ( Baron, B; Boogerd, W; Bravo Marques, J; Chinot, O; De Beule, N; Kros, JM; Taphoorn, MJ; van den Bent, MJ; van der Rijt, CC; Vecht, CJ, 2003)
"The authors administered procarbazine, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU, lomustine), and vincristine (PCV) to 86 patients with recurrent glioblastoma."5.12PCV chemotherapy for recurrent glioblastoma. ( Dichgans, J; Dietz, K; Fischer, J; Herrlinger, U; Schmidt, F; Weller, M, 2006)
"Procarbazine hydrochloride (PCB) is one of the few anticancer drugs with activity against high-grade gliomas."5.12The effect of enzyme-inducing antiseizure drugs on the pharmacokinetics and tolerability of procarbazine hydrochloride. ( Alavi, JB; Batchelor, TT; Carson, KA; Fisher, JD; Grossman, SA; Hammour, T; Lesser, G; Mikkelsen, T; Phuphanich, S; Supko, JG, 2006)
"The aim of this study was to compare tolerance of a nitrosurea-based regime with 'standard' therapy of vincristine (VCR) and carboplatin for low-grade gliomas."5.10Tolerance of nitrosurea-based multiagent chemotherapy regime for low-grade pediatric gliomas. ( Hoddes, JA; Lancaster, DL; Michalski, A, 2003)
"To conduct a Phase II study to evaluate the long-term efficacy and safety of high-dose 5'-bromodeoxyuridine (BrdU) and accelerated radiotherapy followed by procarbazine, lomustine (CCNU), and vincristine (PCV) chemotherapy in patients with glioblastoma multiforme."5.09A phase II trial of high-dose bromodeoxyuridine with accelerated fractionation radiotherapy followed by procarbazine, lomustine, and vincristine for glioblastoma multiforme. ( Bruner, JM; Groves, MD; Hess, K; Jaeckle, KA; Kyritsis, AP; Levin, VA; Maor, MH; Meyers, C; Peterson, P; Sawaya, RE; Yung, WK, 1999)
"To determine whether chemotherapy with temozolomide (TMZ) versus procarbazine (PCB) for recurrent glioblastoma multiforme (GBM) was associated with improvement in health-related quality of life (HRQOL)."5.09Health-related quality of life in patients treated with temozolomide versus procarbazine for recurrent glioblastoma multiforme. ( Brada, M; Osoba, D; Prados, M; Yung, WK, 2000)
" The relative safety of accelerated fractionated radiotherapy, as used in this study with carboplatin, enables concomitant full-dose administration of chemotherapy or radiosensitizing agents in glioblastoma multiforme patients."5.08Phase II study of accelerated fractionation radiation therapy with carboplatin followed by vincristine chemotherapy for the treatment of glioblastoma multiforme. ( Bruner, J; Kyritsis, AP; Leeds, N; Levin, VA; Maor, MH; Rodriguez, L; Sawaya, R; Thall, PF; Woo, S; Yung, WK, 1995)
"To assess the effectiveness and safety of procarbazine, lomustine, and vincristine (PCV) chemotherapy with other interventions in adults with recurrent high-grade glioma."4.95Procarbazine, lomustine and vincristine for recurrent high-grade glioma. ( Guo, J; Parasramka, S; Rosenfeld, M; Talari, G; Villano, JL, 2017)
" In this paper we address different clinical outcomes measures separately and we illustrate the value of multiple outcome measures using the results of a recent clinical trial comparing temozolomide with procarbazine in the treatment of Glioblastoma Multiforme."4.82Benefit of temozolomide compared to procarbazine in treatment of glioblastoma multiforme at first relapse: effect on neurological functioning, performance status, and health related quality of life. ( Kiebert, G; Macdonald, DR; Olson, J; Prados, M; Yung, A, 2005)
" When treated with temozolomide (TMZ), an oral alkylating chemotherapy drug, most low-grade gliomas (LGG) show an initial volume decrease but this effect is rarely long lasting."3.85Analysis of temozolomide resistance in low-grade gliomas using a mechanistic mathematical model. ( Alentorn, A; Delattre, JY; Ducray, F; Grenier, E; Honnorat, J; Idbaih, A; Kaloshi, G; Mazzocco, P; Ollier, E; Psimaras, D; Ricard, D; Samson, A, 2017)
"The addition of procarbazine, lomustine, vincristine (PCV) chemotherapy to radiotherapy (RT) for patients with high-risk (≥40 y old or subtotally resected) low-grade glioma (LGG) results in an absolute median survival benefit of over 5 years."3.85Cost-effectiveness of radiation and chemotherapy for high-risk low-grade glioma. ( Bendavid, E; Chang, DT; Chin, AL; Durkee, BY; Harris, JP; Kim, H; Kumar, KA; Maruyama, S; Owens, DK; Pitt, A; Pollom, EL; Qian, Y; Soltys, SG, 2017)
"The proportion of intravenous drug abusers (IVDA) in HIV-HD (38%) is higher than in French HIV-infected population as a whole (20."3.78Human immunodeficiency virus associated Hodgkin's disease: report of 45 cases from the French Registry of HIV-Associated Tumors. ( Andrieu, JM; Brice, P; Colonna, P; Gastaut, JA; Lévy, R; Raphaël, M; Taillan, B; Tourani, JM, 1995)
"We collected 6 case-reports of symptomatric non removable low grade fibrillary astrocytoma of adults treated with a procarbazine-CCNU-vincristine chemotherapy regimen."3.72[Neoadjuvant chemotherapy for symptomatic non operable grade II fibrillary astrocytoma in adults]. ( Alchaar, H; Bleuse, A; Bondiau, PY; Bourg, V; Brunetto, JL; Chanalet, S; Chatel, M; Courdi, A; Darcourt, J; Fauchon, F; Fontaine, D; Frénay, M; Grellier, P; Guibert, F; Lanteri-Minet, M; Lebrun, C; Lonjon, M; Michiels, JF; Paquis, P; Paquis, V; Ramaioli, A; Rasendrarijao, D; Vandenbos, F, 2004)
"The authors evaluated response, time to progression (TTP), survival, prognostic factors, and toxicity in 63 patients with a recurrent glioblastoma multiforme treated with procarbazine, lomustine, and vincristine (PCV) chemotherapy."3.71PCV chemotherapy for recurrent glioblastoma multiforme. ( Groeneveld, GJ; Heimans, JJ; Kappelle, AC; Postma, TJ; Sneeuw, KC; Taphoorn, MJ; van den Bent, MJ; van Groeningen, CJ; Zonnenberg, BA, 2001)
"We treated 54 patients, newly diagnosed for glioblastoma, with systemic chemotherapy (carmustine (BCNU) 100 mg/m2 and cisplatin 90 mg/m2 every 6 weeks) and radiotherapy soon after surgery."3.70Locally delivered chemotherapy and repeated surgery can improve survival in glioblastoma patients. ( Boiardi, A; Broggi, G; Eoli, M; Pozzi, A; Salmaggi, A; Silvani, A, 1999)
"To determine the efficacy of the combination of 6-thioguanine, procarbazine, lomustine, and hydroxyurea for patients with recurrent malignant gliomas after failure of either previous radiotherapy alone or previous radiotherapy plus nitrosourea-based chemotherapy."3.69Combination of 6-thioguanine, procarbazine, lomustine, and hydroxyurea for patients with recurrent malignant gliomas. ( Bruner, J; Flowers, A; Gleason, MJ; Ictech, SE; Jaeckle, KA; Kyritsis, AP; Levin, VA; Yung, WK, 1996)
"Cilengitide was continued for up to 12 months or until disease progression or unacceptable toxicity."2.82Cilengitide with metronomic temozolomide, procarbazine, and standard radiotherapy in patients with glioblastoma and unmethylated MGMT gene promoter in ExCentric, an open-label phase II trial. ( Ackland, S; Back, M; Buyse, ME; Kerestes, Z; Khasraw, M; Kichenadasse, G; Lee, A; McCowatt, S; Wheeler, H, 2016)
"Based on studies relating to anaplastic oligodendroglioma (OG) chemosensitivity and benefit of time to progression or overall survival, chemotherapy for pure OG has been proposed."2.73Treatment of newly diagnosed symptomatic pure low-grade oligodendrogliomas with PCV chemotherapy. ( Bourg, V; Chanalet, S; Fauchon, F; Fontaine, D; Frenay, M; Lebrun, C; Lonjon, M; Paquis, P; Ramaioli, A; Vandenbos, F, 2007)
"Temozolomide was in general well tolerated; the most frequent side-effects were hematological."2.71Second-line chemotherapy with temozolomide in recurrent oligodendroglioma after PCV (procarbazine, lomustine and vincristine) chemotherapy: EORTC Brain Tumor Group phase II study 26972. ( Baron, B; Boogerd, W; Bravo Marques, J; Chinot, O; De Beule, N; Kros, JM; Taphoorn, MJ; van den Bent, MJ; van der Rijt, CC; Vecht, CJ, 2003)
"Because of the diffuse nature of gliomatosis cerebri (GC), surgery is not suitable, and large field radiotherapy carries the risk of severe toxicity."2.71Initial chemotherapy in gliomatosis cerebri. ( Carpentier, A; Cartalat-Carel, S; Chinot, O; Cougnard, J; Delattre, JY; Djafari, L; Duffau, H; Gervais, H; Hoang-Xuan, K; Honnorat, J; Laigle, F; Mokhtari, K; Napolitano, M; Sanson, M; Taillandier, L; Taillibert, S, 2004)
" Despite increased hematotoxicity, moderate dose escalation is safe for the majority of the patients with G-CSF assistance and standard supportive treatment."2.69Acute hematologic toxicity and practicability of dose-intensified BEACOPP chemotherapy for advanced stage Hodgkin's disease. German Hodgkin's Lymphoma Study Group (GHSG). ( Diehl, V; Engel, C; Loeffler, M; Schmitz, S; Tesch, H, 2000)
"We document a high incidence of aseptic bone necrosis, possibly related to prednisolone."1.38Two escalated followed by six standard BEACOPP in advanced-stage high-risk classical Hodgkin lymphoma: high cure rates but increased risk of aseptic osteonecrosis. ( Aurlien, E; Blystad, AK; Fiskvik, IH; Fosså, A; Hole, KH; Holte, H; Ikonomou, IM; Kolstad, A; Lauritzsen, GF, 2012)
"The treatment results of our Hodgkin's disease patients improved, additionally we showed that patients with early stage favourable disease the treatment toxicity should be reduced, while patients with advanced, unfavourable prognosis (10% of all patients) aggressive primary treatment should be used even with more severe side effects and complications."1.34[Our experiences in treating patients with Hodgkin disease in the last decade]. ( Gergely, L; Illés, A; Keresztes, K; Miltényi, Z; Ress, Z; Simon, Z; Vadász, G; Váróczy, L, 2007)
"Treatment strategies in Hodgkin's disease have an impact on different risk factors."1.32Does bulky disease at diagnosis influence outcome in childhood Hodgkin's disease and require higher radiation doses? Results from the German-Austrian Pediatric Multicenter Trial DAL-HD-90. ( Dieckmann, K; Heinzl, H; Hofmann, J; Pötter, R; Schellong, G; Wagner, W, 2003)
"One hundred and fifty-six patients with multiple myeloma were treated over a period of 12 years at St."1.29Myeloma during a decade: clinical experience in a single centre. ( Carter, M; Clark, PI; Ganjoo, RK; Gregory, W; Johnson, PW; Lim, JM; Love, SB; Mahmoud, MM; Malpas, JS; Williams, AH, 1995)

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's19 (24.05)18.2507
2000's39 (49.37)29.6817
2010's20 (25.32)24.3611
2020's1 (1.27)2.80

Authors

AuthorsStudies
André, MPE1
Carde, P2
Viviani, S2
Bellei, M1
Fortpied, C1
Hutchings, M1
Gianni, AM2
Brice, P3
Casasnovas, O1
Gobbi, PG1
Zinzani, PL1
Dupuis, J1
Iannitto, E1
Rambaldi, A1
Brière, J1
Clément-Filliatre, L1
Heczko, M1
Valagussa, P2
Douxfils, J1
Depaus, J1
Federico, M1
Mounier, N1
Skoetz, N1
Will, A1
Monsef, I1
Brillant, C1
Engert, A8
von Tresckow, B1
Qian, Y1
Maruyama, S1
Kim, H1
Pollom, EL1
Kumar, KA1
Chin, AL1
Harris, JP1
Chang, DT1
Pitt, A1
Bendavid, E1
Owens, DK1
Durkee, BY1
Soltys, SG1
Parasramka, S1
Talari, G1
Rosenfeld, M1
Guo, J1
Villano, JL1
Fong, M1
Boyle, S1
Gutta, N1
Cairncross, JG2
Wang, M1
Jenkins, RB2
Shaw, EG1
Giannini, C1
Brachman, DG1
Buckner, JC2
Fink, KL1
Souhami, L1
Laperriere, NJ1
Huse, JT1
Mehta, MP1
Curran, WJ2
Taal, W1
van der Rijt, CC2
Dinjens, WN1
Sillevis Smitt, PA3
Wertenbroek, AA1
Bromberg, JE1
van Heuvel, I1
Kros, JM3
van den Bent, MJ5
Ganesan, P1
Rajendranath, R1
Kannan, K1
Radhakrishnan, V1
Ganesan, TS1
Udupa, K1
Lakshmipathy, KM1
Mahajan, V1
Sundersingh, S1
Rajaraman, S1
Krishnakumar, R1
Sagar, TG1
Schiff, D2
Khasraw, M1
Lee, A1
McCowatt, S1
Kerestes, Z1
Buyse, ME1
Back, M1
Kichenadasse, G1
Ackland, S1
Wheeler, H1
Ollier, E1
Mazzocco, P1
Ricard, D1
Kaloshi, G1
Idbaih, A1
Alentorn, A1
Psimaras, D1
Honnorat, J2
Delattre, JY2
Grenier, E1
Ducray, F2
Samson, A1
Markova, J1
Kobe, C1
Skopalova, M1
Klaskova, K1
Dedeckova, K1
Plütschow, A1
Eich, HT2
Dietlein, M1
Kozak, T1
Nicolin, G1
Parkin, P1
Mabbott, D1
Hargrave, D1
Bartels, U1
Tabori, U1
Rutka, J1
Buncic, JR1
Bouffet, E1
Wick, W1
Hartmann, C1
Engel, C2
Stoffels, M1
Felsberg, J2
Stockhammer, F1
Sabel, MC1
Koeppen, S1
Ketter, R1
Meyermann, R1
Rapp, M1
Meisner, C1
Kortmann, RD1
Pietsch, T1
Wiestler, OD1
Ernemann, U1
Bamberg, M2
Reifenberger, G2
von Deimling, A1
Weller, M3
Mishra, KK1
Squire, S1
Lamborn, K2
Banerjee, A1
Gupta, N1
Wara, WM1
Prados, MD4
Berger, MS1
Haas-Kogan, DA1
Sangave, A1
Faia, LJ1
Yeh, S1
Chan, CC1
Nussenblatt, RB1
Sen, HN1
Halbsguth, TV1
Nogová, L1
Mueller, H1
Sieniawski, M1
Eichenauer, DA1
Schober, T1
Nisters-Backes, H1
Borchmann, P2
Diehl, V8
Josting, A3
Lassman, AB1
Iwamoto, FM1
Cloughesy, TF1
Aldape, KD1
Rivera, AL1
Eichler, AF1
Louis, DN1
Paleologos, NA1
Fisher, BJ1
Ashby, LS1
Roldán, GB1
Wen, PY1
Ligon, KL1
Robins, HI1
Rocque, BG1
Chamberlain, MC2
Mason, WP1
Weaver, SA1
Green, RM1
Kamar, FG1
Abrey, LE2
DeAngelis, LM2
Jhanwar, SC1
Rosenblum, MK2
Panageas, KS1
Glas, M1
Bähr, O1
Rasch, K1
Wiewrodt, D1
Schabet, M1
Simon, M1
Urbach, H1
Steinbach, JP1
Rieger, J1
Fimmers, R1
Nägele, T1
Herrlinger, U2
Lim, SH1
Johnson, PW3
Fosså, A1
Fiskvik, IH1
Kolstad, A1
Lauritzsen, GF1
Aurlien, E1
Blystad, AK1
Hole, KH1
Ikonomou, IM1
Holte, H1
Bruessow, C1
Karrer, U1
Gubler, J1
Pless, M1
Looijenga, LH1
Langenberg, K1
Dinjens, W1
Graveland, W1
Uytdewilligen, L1
Chinot, O2
Boogerd, W1
Bravo Marques, J1
Taphoorn, MJ2
Vecht, CJ1
De Beule, N1
Baron, B1
Sunyach, MP1
Pommier, P1
Martel Lafay, I1
Guyotat, J1
Ginestet, G1
Jouanneau, E1
Jouvet, A1
Sindou, M1
Bret, P1
Carrie, C1
Frappaz, D1
Sieber, M3
Bredenfeld, H1
Reineke, T1
Rueffer, U1
Koch, T1
Naumann, R1
Boissevain, F3
Koch, P3
Worst, P2
Soekler, M1
Eich, H1
Müller-Hermelink, HK2
Franklin, J3
Paulus, U2
Wolf, J3
Dieckmann, K1
Pötter, R1
Hofmann, J1
Heinzl, H1
Wagner, W1
Schellong, G1
Lancaster, DL1
Hoddes, JA1
Michalski, A1
Schiller, P1
Herrmann, R1
De Wit, M1
Mezger, J1
Duhmke, E3
Willich, N1
Muller, RP2
Schmidt, BF1
Renner, H1
Pfistner, B2
Hasenclever, D2
Loffler, M1
Lai, R1
Pandya, KJ1
Lefkopoulou, M1
Petrelli, NJ1
Vaughn, DJ1
Smith, TJ1
Harris, JE1
Haller, DG1
Lebrun, C2
Fontaine, D2
Vandenbos, F2
Chanalet, S2
Bourg, V2
Frénay, M2
Alchaar, H1
Bleuse, A1
Bondiau, PY1
Brunetto, JL1
Chatel, M1
Courdi, A1
Darcourt, J1
Fauchon, F2
Guibert, F1
Grellier, P1
Lanteri-Minet, M1
Lonjon, M2
Michiels, JF1
Paquis, P2
Paquis, V1
Ramaioli, A2
Rasendrarijao, D1
Sanson, M1
Cartalat-Carel, S1
Taillibert, S1
Napolitano, M1
Djafari, L1
Cougnard, J1
Gervais, H1
Laigle, F1
Carpentier, A1
Mokhtari, K1
Taillandier, L1
Duffau, H1
Hoang-Xuan, K1
de Wit, MC1
de Bruin, HG1
Eijkenboom, W1
Hudson, MM1
Krasin, M1
Link, MP1
Donaldson, SS1
Billups, C1
Merchant, TE1
Kun, L1
Billet, AL1
Kaste, S1
Tarbell, NJ1
Howard, S1
Friedmann, AM1
Hurwitz, CA1
Young, JA1
Marcus, KC1
Rai, S1
Cowan, T1
Weinstein, HJ1
Macdonald, DR1
Kiebert, G1
Prados, M2
Yung, A1
Olson, J1
Bonadonna, G1
Bonfante, V1
Fisher, B1
Seiferheld, W1
Schultz, C2
DeAngelis, L1
Nelson, D1
Schold, SC1
Curran, W1
Mehta, M1
Radford, JA1
Cullen, MH1
Sydes, MR1
Walewski, J1
Jack, AS1
MacLennan, KA1
Stenning, SP1
Clawson, S1
Smith, P1
Ryder, D1
Hancock, BW1
Schmidt, F1
Fischer, J1
Dietz, K1
Dichgans, J1
Piccirilli, M1
Landi, A1
Salvati, M1
Grossman, SA1
Carson, KA1
Batchelor, TT1
Lesser, G1
Mikkelsen, T2
Alavi, JB1
Phuphanich, S1
Hammour, T1
Fisher, JD1
Supko, JG1
Walker, C1
Haylock, B1
Husband, D1
Joyce, KA1
Fildes, D1
Jenkinson, MD1
Smith, T1
Broome, J1
Kopitzki, K1
du Plessis, DG1
Prosser, J1
Vinjamuri, S1
Warnke, PC1
Klimm, B1
Haverkamp, H1
Lohri, A1
Trenn, G1
Müller-Hermelink, K1
Simon, Z1
Keresztes, K1
Miltényi, Z1
Ress, Z1
Váróczy, L1
Vadász, G1
Gergely, L1
Illés, A1
Yang, SH1
Hong, YK1
Yoon, SC1
Kim, BS1
Lee, YS1
Lee, TK1
Lee, KS1
Jeun, SS1
Kim, MC1
Park, CK1
Gill, P1
Litzow, M1
Buckner, J1
Arndt, C1
Moynihan, T1
Christianson, T1
Ansell, S1
Galanis, E1
Lévy, R1
Colonna, P1
Tourani, JM1
Gastaut, JA1
Raphaël, M1
Taillan, B1
Andrieu, JM1
Levin, VA6
Maor, MH2
Thall, PF1
Yung, WK6
Bruner, J2
Sawaya, R1
Kyritsis, AP5
Leeds, N1
Woo, S1
Rodriguez, L1
Malpas, JS1
Ganjoo, RK1
Mahmoud, MM1
Williams, AH1
Carter, M1
Gregory, W1
Lim, JM1
Love, SB1
Clark, PI1
Jeremic, B1
Grujicic, D1
Antunovic, V1
Djuric, L1
Stojanovic, M1
Shibamoto, Y1
Haim, N1
Leviov, M1
Ben-Arieh, Y1
Epelbaum, R1
Freidin, N1
Reshef, R1
Ben-Shahar, M1
Jaeckle, KA4
Gleason, MJ1
Ictech, SE1
Flowers, A1
Edwards, MS1
Rabbitt, J1
Davis, RL1
Kaba, SE1
Hess, K2
Mercier, R1
Dakhil, S1
Davidge-Pitts, M1
Dansey, R1
Bezwoda, WR1
Wirth, A1
Corry, J1
Laidlaw, C1
Matthews, J1
Liew, KH1
Mac Manus, MP1
Hoppe, RT1
Tesch, H2
Pfreundschuh, M1
Lathan, B1
Rüffer, JU1
Sextro, M1
Hermann, R1
Holmer, L1
Stappert-Jahn, U1
Winnerlein-Trump, E1
Wulf, G1
Krause, S1
Glunz, A1
von Kalle, K1
Bischoff, H1
Haedicke, C1
Georgii, A1
Loeffler, M2
Brandes, AA1
Ermani, M1
Turazzi, S1
Scelzi, E1
Berti, F1
Amistà, P1
Rotilio, A1
Licata, C1
Fiorentino, MV1
Saletti, P1
Zucca, E1
Gueneau, M1
Peccatori, F1
Cavalli, F2
Martinelli, G1
Groves, MD1
Meyers, C1
Sawaya, RE1
Bruner, JM1
Peterson, P1
Scott, C1
Sandler, H1
Phillips, T1
Urtasun, R1
Davis, R1
Gutin, P1
Cascino, TL1
Greenberg, HS1
Meddeb, B1
Ben Lakhal, R1
Bel Hadj Ali, Z1
Ben Abid, H1
Hafsia, R1
Hafsia, A1
Osoba, D1
Brada, M1
Fisher, RI1
Dana, BW1
LeBlanc, M1
Kjeldsberg, C1
Forman, JD1
Unger, JM1
Balcerzak, SP1
Gaynor, ER1
Roy, V1
Miller, T1
Boiardi, A2
Eoli, M1
Pozzi, A1
Salmaggi, A1
Broggi, G1
Silvani, A1
Schmitz, S1
Kappelle, AC1
Postma, TJ1
Groeneveld, GJ1
van Groeningen, CJ1
Zonnenberg, BA1
Sneeuw, KC1
Heimans, JJ1
Cairncross, G1
Swinnen, L1
Bayer, R1
Rosenfeld, S1
Salzman, D1
Paleologos, N1
Kaminer, L1
Forsyth, P1
Stewart, D1
Peterson, K1
Hu, W1
Macdonald, D1
Ramsay, D1
Smith, A1
Colin, P1
Berger, F1
de Kerviler, E1
Diviné, M1
Bouaffia, F1
Kerneis, Y1
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Hess, KR1
Wong, ET1
Croteau, D1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Study of Interim PET-CT Scan-guided Response Adapted Therapy in Hodgkin's Lymphoma[NCT01304849]50 participants (Actual)Interventional2011-01-31Completed
[NCT00284271]Phase 265 participants (Actual)Interventional2004-01-31Completed
A Phase Ib/II Trial of Combined SGN-35 (BrentuximabVedotin) Therapy With Cyclophosphamide, Procarbazine, Prednisone, Etoposide and Mitoxantrone (BrEPEM) for Older Patients With Untreated Hodgkin Lymphoma (HL)[NCT03576378]Phase 1/Phase 241 participants (Actual)Interventional2018-08-08Active, not recruiting
Second Line Chemotherapy With Temozolomide in Recurrent Oligodendroglial Tumors After PCV-Chemotherapy[NCT00003304]Phase 229 participants (Anticipated)Interventional1998-04-30Completed
A UKLG Randomised Trial of Initial Chemotherapy for Advanced Stage Hodgkins Disease[NCT00003421]Phase 3800 participants (Anticipated)Interventional1998-06-30Completed
Optimization of the Primary Therapy for Patients With Hodgkin's Lymphoma and Evaluation of the Positron Emission Tomography (PET) as a Diagnostic Tool for Primary Staging and Assessment of the Effects of the Therapy[NCT00188149]Phase 4300 participants Interventional2000-05-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

14 reviews available for procarbazine and Disease Exacerbation

ArticleYear
Long-term overall survival and toxicities of ABVD vs BEACOPP in advanced Hodgkin lymphoma: A pooled analysis of four randomized trials.
    Cancer medicine, 2020, Volume: 9, Issue:18

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials,

2020
Comparison of first-line chemotherapy including escalated BEACOPP versus chemotherapy including ABVD for people with early unfavourable or advanced stage Hodgkin lymphoma.
    The Cochrane database of systematic reviews, 2017, 05-25, Volume: 5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Daca

2017
Procarbazine, lomustine and vincristine for recurrent high-grade glioma.
    The Cochrane database of systematic reviews, 2017, 07-26, Volume: 7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cytarabine; Dacarbazine; Dis

2017
Low-grade gliomas.
    Continuum (Minneapolis, Minn.), 2015, Volume: 21, Issue:2 Neuro-on

    Topics: Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Disease Progression;

2015
Chemotherapy for diffuse low-grade gliomas in adults.
    Revue neurologique, 2011, Volume: 167, Issue:10

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Chemother

2011
Conformal irradiation for pure and mixed oligodendroglioma: the experience of Centre Leon Berard Lyon.
    International journal of radiation oncology, biology, physics, 2003, May-01, Volume: 56, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brain Damage, Chronic; Brain Injuries

2003
Treatment-induced leukoencephalopathy in primary CNS lymphoma: a clinical and autopsy study.
    Neurology, 2004, Feb-10, Volume: 62, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Cranial Irradia

2004
Immediate post-radiotherapy changes in malignant glioma can mimic tumor progression.
    Neurology, 2004, Aug-10, Volume: 63, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Artifacts; Astrocytoma; Brain Edema; Brain Neoplasms

2004
Benefit of temozolomide compared to procarbazine in treatment of glioblastoma multiforme at first relapse: effect on neurological functioning, performance status, and health related quality of life.
    Cancer investigation, 2005, Volume: 23, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Clinical Trials as Topic;

2005
Human immunodeficiency virus associated Hodgkin's disease: report of 45 cases from the French Registry of HIV-Associated Tumors.
    Leukemia & lymphoma, 1995, Volume: 16, Issue:5-6

    Topics: Adult; AIDS-Related Opportunistic Infections; Antineoplastic Combined Chemotherapy Protocols; Bleomy

1995
Overview of treatment of localized low-grade lymphomas.
    Hematology/oncology clinics of North America, 1997, Volume: 11, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; California; Chemotherap

1997
BEACOPP: a new regimen for advanced Hodgkin's disease. German Hodgkin's Lymphoma Study Group.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1998, Volume: 9 Suppl 5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit

1998
Is escalated BEACOPP a standard therapy for advanced Hodgkin's disease?
    The hematology journal : the official journal of the European Haematology Association, 2000, Volume: 1, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Clinical Trials, Phase III

2000
Adults with newly diagnosed high-grade gliomas.
    Current treatment options in oncology, 2001, Volume: 2, Issue:6

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Antioxidan

2001

Trials

37 trials available for procarbazine and Disease Exacerbation

ArticleYear
Benefit from procarbazine, lomustine, and vincristine in oligodendroglial tumors is associated with mutation of IDH.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Mar-10, Volume: 32, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Chi-Square Distr

2014
Phase II study of interim PET-CT-guided response-adapted therapy in advanced Hodgkin's lymphoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Cyclophosphamid

2015
Cilengitide with metronomic temozolomide, procarbazine, and standard radiotherapy in patients with glioblastoma and unmethylated MGMT gene promoter in ExCentric, an open-label phase II trial.
    Journal of neuro-oncology, 2016, Volume: 128, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Central Nervous System Neoplasms; Chemoradiotherapy; Dacarbazine

2016
FDG-PET for assessment of early treatment response after four cycles of chemotherapy in patients with advanced-stage Hodgkin's lymphoma has a high negative predictive value.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20, Issue:7

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Dise

2009
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Dec-10, Volume: 27, Issue:35

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brai

2009
Phase II TPDCV protocol for pediatric low-grade hypothalamic/chiasmatic gliomas: 15-year update.
    Journal of neuro-oncology, 2010, Volume: 100, Issue:1

    Topics: Adolescent; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Di

2010
Phase 2 study of BACOPP (bleomycin, adriamycin, cyclophosphamide, vincristine, procarbazine, and prednisone) in older patients with Hodgkin lymphoma: a report from the German Hodgkin Study Group (GHSG).
    Blood, 2010, Sep-23, Volume: 116, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Disease Progressi

2010
Phase 2 study of BACOPP (bleomycin, adriamycin, cyclophosphamide, vincristine, procarbazine, and prednisone) in older patients with Hodgkin lymphoma: a report from the German Hodgkin Study Group (GHSG).
    Blood, 2010, Sep-23, Volume: 116, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Disease Progressi

2010
Phase 2 study of BACOPP (bleomycin, adriamycin, cyclophosphamide, vincristine, procarbazine, and prednisone) in older patients with Hodgkin lymphoma: a report from the German Hodgkin Study Group (GHSG).
    Blood, 2010, Sep-23, Volume: 116, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Disease Progressi

2010
Phase 2 study of BACOPP (bleomycin, adriamycin, cyclophosphamide, vincristine, procarbazine, and prednisone) in older patients with Hodgkin lymphoma: a report from the German Hodgkin Study Group (GHSG).
    Blood, 2010, Sep-23, Volume: 116, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Disease Progressi

2010
NOA-05 phase 2 trial of procarbazine and lomustine therapy in gliomatosis cerebri.
    Annals of neurology, 2011, Volume: 70, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumo

2011
Second-line chemotherapy with temozolomide in recurrent oligodendroglioma after PCV (procarbazine, lomustine and vincristine) chemotherapy: EORTC Brain Tumor Group phase II study 26972.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:4

    Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

2003
14-day variant of the bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone regimen in advanced-stage Hodgkin's lymphoma: results of a pilot study of the German Hodgkin's Lymphoma Study Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, May-01, Volume: 21, Issue:9

    Topics: Adolescent; Adult; Anemia; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphami

2003
Tolerance of nitrosurea-based multiagent chemotherapy regime for low-grade pediatric gliomas.
    Journal of neuro-oncology, 2003, Volume: 63, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Child; Chi

2003
Involved-field radiotherapy is equally effective and less toxic compared with extended-field radiotherapy after four cycles of chemotherapy in patients with early-stage unfavorable Hodgkin's lymphoma: results of the HD8 trial of the German Hodgkin's Lymph
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Oct-01, Volume: 21, Issue:19

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide

2003
Phase II study of cisplatin and 5-fluorouracil (PF) and mitomycin C, vincristine, cisplatin and 5-fluorouracil (MVPF) in patients with metastatic large bowel cancer: an Eastern Cooperative Oncology Group study (EST 1285).
    Oncology, 2004, Volume: 66, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colonic Neoplasms; Disease Progression; D

2004
Initial chemotherapy in gliomatosis cerebri.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Antineoplastic Combin

2004
Immediate post-radiotherapy changes in malignant glioma can mimic tumor progression.
    Neurology, 2004, Aug-10, Volume: 63, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Artifacts; Astrocytoma; Brain Edema; Brain Neoplasms

2004
Risk-adapted, combined-modality therapy with VAMP/COP and response-based, involved-field radiation for unfavorable pediatric Hodgkin's disease.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Nov-15, Volume: 22, Issue:22

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined

2004
Secondary analysis of Radiation Therapy Oncology Group study (RTOG) 9310: an intergroup phase II combined modality treatment of primary central nervous system lymphoma.
    Journal of neuro-oncology, 2005, Volume: 74, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Neoplasms; Cognition; Combined Modality

2005
Comparison of ABVD and alternating or hybrid multidrug regimens for the treatment of advanced Hodgkin's lymphoma: results of the United Kingdom Lymphoma Group LY09 Trial (ISRCTN97144519).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Dec-20, Volume: 23, Issue:36

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Co

2005
PCV chemotherapy for recurrent glioblastoma.
    Neurology, 2006, Feb-28, Volume: 66, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Disease Progression; D

2006
The effect of enzyme-inducing antiseizure drugs on the pharmacokinetics and tolerability of procarbazine hydrochloride.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Sep-01, Volume: 12, Issue:17

    Topics: Administration, Oral; Adult; Aged; Anticonvulsants; Antineoplastic Agents; Cohort Studies; Disease P

2006
Poorer outcome of elderly patients treated with extended-field radiotherapy compared with involved-field radiotherapy after chemotherapy for Hodgkin's lymphoma: an analysis from the German Hodgkin Study Group.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit

2007
Treatment of newly diagnosed symptomatic pure low-grade oligodendrogliomas with PCV chemotherapy.
    European journal of neurology, 2007, Volume: 14, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Disease Progression; Disease

2007
Human immunodeficiency virus associated Hodgkin's disease: report of 45 cases from the French Registry of HIV-Associated Tumors.
    Leukemia & lymphoma, 1995, Volume: 16, Issue:5-6

    Topics: Adult; AIDS-Related Opportunistic Infections; Antineoplastic Combined Chemotherapy Protocols; Bleomy

1995
Phase II study of accelerated fractionation radiation therapy with carboplatin followed by vincristine chemotherapy for the treatment of glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 1995, Sep-30, Volume: 33, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Chemother

1995
Intermediate and high-grade gastric non-Hodgkin's lymphoma: a prospective study of non-surgical treatment with primary chemotherapy, with or without radiotherapy.
    Leukemia & lymphoma, 1995, Volume: 17, Issue:3-4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease Progression;

1995
Treatment of pediatric low-grade gliomas with a nitrosourea-based multiagent chemotherapy regimen.
    Journal of neuro-oncology, 1997, Volume: 32, Issue:3

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Preschool

1997
TPDC-FuHu chemotherapy for the treatment of recurrent metastatic brain tumors.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:3

    Topics: Adenocarcinoma; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neop

1997
BEACOPP: a new regimen for advanced Hodgkin's disease. German Hodgkin's Lymphoma Study Group.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1998, Volume: 9 Suppl 5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modalit

1998
Procarbazine and high-dose tamoxifen as a second-line regimen in recurrent high-grade gliomas: a phase II study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain; Brain N

1999
A phase II trial of high-dose bromodeoxyuridine with accelerated fractionation radiotherapy followed by procarbazine, lomustine, and vincristine for glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 1999, Aug-01, Volume: 45, Issue:1

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Brain

1999
A phase 3 randomized study of radiotherapy plus procarbazine, CCNU, and vincristine (PCV) with or without BUdR for the treatment of anaplastic astrocytoma: a preliminary report of RTOG 9404.
    International journal of radiation oncology, biology, physics, 1999, Dec-01, Volume: 45, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Bromodeoxyuridine; Che

1999
[Results of a prospective protocol for the treatment of adult Hodgkin's disease].
    La Tunisie medicale, 1999, Volume: 77, Issue:12

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Disease Progression; D

1999
Health-related quality of life in patients treated with temozolomide versus procarbazine for recurrent glioblastoma multiforme.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine;

2000
Interferon alpha consolidation after intensive chemotherapy does not prolong the progression-free survival of patients with low-grade non-Hodgkin's lymphoma: results of the Southwest Oncology Group randomized phase III study 8809.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:10

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Disease Progression;

2000
Acute hematologic toxicity and practicability of dose-intensified BEACOPP chemotherapy for advanced stage Hodgkin's disease. German Hodgkin's Lymphoma Study Group (GHSG).
    Annals of oncology : official journal of the European Society for Medical Oncology, 2000, Volume: 11, Issue:9

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Blood Platelets;

2000
Advanced Hodgkin disease with large mediastinal involvement can be treated with eight cycles of chemotherapy alone after a major response to six cycles of chemotherapy: a study of 82 patients from the Groupes d'Etudes des Lymphomes de l'Adulte H89 trial.
    Cancer, 2001, Aug-01, Volume: 92, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Disease Progression; Doxorubicin;

2001
Response and progression in recurrent malignant glioma.
    Neuro-oncology, 1999, Volume: 1, Issue:4

    Topics: Actuarial Analysis; Adolescent; Adult; Aged; Aged, 80 and over; Alitretinoin; Antineoplastic Combine

1999

Other Studies

31 other studies available for procarbazine and Disease Exacerbation

ArticleYear
Cost-effectiveness of radiation and chemotherapy for high-risk low-grade glioma.
    Neuro-oncology, 2017, Nov-29, Volume: 19, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Cost-Bene

2017
Brentuximab vedotin in combination with sequential procarbazine, cyclophosphamide and prednisolone for the management of Hodgkin's lymphoma-associated vanishing bile duct syndrome (VBDS) with severe obstructive liver failure.
    BMJ case reports, 2019, Feb-21, Volume: 12, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Diseases; Brentuximab Vedotin; Cycl

2019
Treatment of large low-grade oligodendroglial tumors with upfront procarbazine, lomustine, and vincristine chemotherapy with long follow-up: a retrospective cohort study with growth kinetics.
    Journal of neuro-oncology, 2015, Volume: 121, Issue:2

    Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Disease Progression; Drug Therapy, Combination; Femal

2015
Analysis of temozolomide resistance in low-grade gliomas using a mechanistic mathematical model.
    Fundamental & clinical pharmacology, 2017, Volume: 31, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Dise

2017
Natural history and outcome of optic pathway gliomas in children.
    Pediatric blood & cancer, 2009, Dec-15, Volume: 53, Issue:7

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Damage, Chronic; Carboplatin; Chil

2009
A case of rapid progression and vision loss in a patient with primary intraocular lymphoma.
    Ocular immunology and inflammation, 2010, Volume: 18, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Blindness; Disease Progression; Eye Neoplasms;

2010
International retrospective study of over 1000 adults with anaplastic oligodendroglial tumors.
    Neuro-oncology, 2011, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chr

2011
Chemotherapy: Advanced Hodgkin lymphoma--balancing toxicity and cure.
    Nature reviews. Clinical oncology, 2011, Sep-06, Volume: 8, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Consolidation

2011
Two escalated followed by six standard BEACOPP in advanced-stage high-risk classical Hodgkin lymphoma: high cure rates but increased risk of aseptic osteonecrosis.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chemotherapy, Adjuvant

2012
Chemotherapy: Hodgkin lymphoma--absence of evidence not evidence of absence!
    Nature reviews. Clinical oncology, 2011, Oct-04, Volume: 8, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Bleomycin; Combined Modality Therapy; Cy

2011
Homonymous hemianopsia in a patient with Hodgkin's lymphoma in remission after BEACOPP chemotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Apr-20, Volume: 30, Issue:12

    Topics: Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Bleomycin;

2012
Chromosomal anomalies in oligodendroglial tumors are correlated with clinical features.
    Cancer, 2003, Mar-01, Volume: 97, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chromosome Aberrations; Chromosomes

2003
Does bulky disease at diagnosis influence outcome in childhood Hodgkin's disease and require higher radiation doses? Results from the German-Austrian Pediatric Multicenter Trial DAL-HD-90.
    International journal of radiation oncology, biology, physics, 2003, Jul-01, Volume: 56, Issue:3

    Topics: Adolescent; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Pres

2003
[Neoadjuvant chemotherapy for symptomatic non operable grade II fibrillary astrocytoma in adults].
    Revue neurologique, 2004, Volume: 160, Issue:5 Pt 1

    Topics: Adult; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Astrocytom

2004
Gliomatosis cerebri: better definition, better treatment.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Astrocyt

2004
Survival in Hodgkin's disease patients--report of 25 years of experience at the Milan Cancer Institute.
    European journal of cancer (Oxford, England : 1990), 2005, Volume: 41, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cause of Death; Dacarbazine; Disea

2005
Gliomatosis cerebri treatment in 11 elderly patients.
    Journal of experimental & clinical cancer research : CR, 2006, Volume: 25, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined M

2006
Genetic and metabolic predictors of chemosensitivity in oligodendroglial neoplasms.
    British journal of cancer, 2006, Nov-20, Volume: 95, Issue:10

    Topics: Adult; Aged; Alleles; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chromosomes,

2006
[Our experiences in treating patients with Hodgkin disease in the last decade].
    Orvosi hetilap, 2007, Apr-15, Volume: 148, Issue:15

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chemotherapy, Ad

2007
Radiotherapy plus concurrent and adjuvant procarbazine, lomustine, and vincristine chemotherapy for patients with malignant glioma.
    Oncology reports, 2007, Volume: 17, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemothera

2007
High-dose chemotherapy with autologous stem cell transplantation in adults with recurrent embryonal tumors of the central nervous system.
    Cancer, 2008, Apr-15, Volume: 112, Issue:8

    Topics: Adult; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic;

2008
Myeloma during a decade: clinical experience in a single centre.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1995, Volume: 6, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transpla

1995
Influence of extent of surgery and tumor location on treatment outcome of patients with glioblastoma multiforme treated with combined modality approach.
    Journal of neuro-oncology, 1994, Volume: 21, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brain Neoplasms; Carmustine; Ch

1994
Combination of 6-thioguanine, procarbazine, lomustine, and hydroxyurea for patients with recurrent malignant gliomas.
    Neurosurgery, 1996, Volume: 39, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Disease Pr

1996
Salvage treatment after failure or relapse following initial chemotherapy for follicular non-Hodgkin's lymphoma.
    Leukemia & lymphoma, 1997, Volume: 24, Issue:3-4

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Cycl

1997
Salvage radiotherapy for Hodgkin's disease following chemotherapy failure.
    International journal of radiation oncology, biology, physics, 1997, Oct-01, Volume: 39, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Child; Dacarbazine; Di

1997
ChlVPP/ABV-VP16 hybrid regimen for advanced Hodgkin's disease: a study in 36 patients.
    Leukemia & lymphoma, 1999, Volume: 33, Issue:3-4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Disease Progre

1999
Locally delivered chemotherapy and repeated surgery can improve survival in glioblastoma patients.
    Italian journal of neurological sciences, 1999, Volume: 20, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Carmustine; Chemotherapy

1999
PCV chemotherapy for recurrent glioblastoma multiforme.
    Neurology, 2001, Jan-09, Volume: 56, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Female; Glioblasto

2001
Myeloablative chemotherapy for recurrent aggressive oligodendroglioma.
    Neuro-oncology, 2000, Volume: 2, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone Marrow Transplanta

2000
PCV chemotherapy for recurrent glioblastoma multiforme.
    Neurology, 2001, Jun-26, Volume: 56, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Disease Progression; Female; Gliobl

2001